Allergodil nasal spray 10 ml.

Qualitative and quantitative composition
Active substance :
One injection (equivalent to 0,14 ml solution) containing 0,14 mg azelastine hydrochloride.
Excipients:
Hypromellose , EDTA disodium salt dihydrate, citric acid anhydrous , dibasic sodium phosphate dodecahydrate , sodium chloride , distilled water.
 
 
Formulation and CONTENTS
Nasal spray, solution
Bottle containing 10 ml of solution.
 

Pharmacotherapeutic group and mode of action
Allergy medicine for nasal administration.
Allergy is a hyperresponsiveness of the body's own immune system of the organism against a relatively harmless substance . Allergic reaction may occur eg . in contact with pollen, dust mites , cat or dog hair .
To relieve your allergy symptoms , your doctor prescribes Allergodil ® nasal spray containing the active veshtetvo azelastine hydrochloride. This substance inhibits the action of histamine and other inflammatory substances that are released in a large amount in the presence of an allergy . Furthermore, reducing the increased secretion from the nose , itching and swelling of the nasal mucosa . Despite the low dose drug is rapid and effective reduction of allergic symptoms, as Allergodil ® Nasal Spray implemented its action directly on the nasal mucosa.
 
indications
Symptomatic treatment of hay fever (seasonal allergic rhinitis) or non-seasonal ( perennial) allergic rhinitis.
 
 
Contraindications
In what cases should not apply Allergodil nasal spray ?
Allergodil nasal spray should not be used in patients with known hypersensitivity to azelastine hydrochloride or any of the excipients (see " Qualitative and quantitative composition ').
 
 
Drug interactions and other forms of interaction
So far, no interactions were observed with other medicinal products and food. It is generally recommended to avoid consumption of alcoholic beverages during the administration of drugs.
 
 
What should be considered in children and elderly patients adults ?
Allergodil nasal spray should not be used in children under 6 years of age. No special precautions for use in elderly patients .
 
 
What you should consider during pregnancy and lactation ?
Data on Allergodil a nasal spray during pregnancy and lactation in humans. Following oral administration of high doses in animals 1875 times higher than the recommended daily dose intranasal administration in humans , mortality , growth retardation and increased incidence of skeletal malformations in reproductive toxicity studies . Therefore Allergodil nasal spray is not recommended to be applied in the first trimester of pregnancy . It is not known whether azelastine hydrochloride is excreted in human milk. Therefore Allergodil nasal spray is not recommended to be used during lactation.
If you are pregnant or breastfeeding , talk to your doctor before you start using Allergodil nasal spray .
 
Effects on ability to drive and use machines without safe foothold
In isolated cases in the application of Allergodil nasal spray can be observed fatigue , weakness , fatigue , dizziness, which may be due to the disease. In this case we can impair the ability to drive and use machines. Alcohol may intensify this effect.
Dose , route and duration of administration
The following data are valid in the event that your doctor has prescribed something for Allergodil nasal spray . Please adhere to the recommendations for application, otherwise Allergodil nasal spray may not have the desired effect.
 
 
How often and how much Allergodil nasal spray to be applied ?
Adults and children over 6 years
In the absence of specific prescription from your doctor , Allergodil nasal spray is sprayed into each nostril 2 times a day - morning and evening ( equivalent to a daily dose of 0,56 mg azelastine hydrochloride).
 
 
How to use Allergodil nasal spray ?
The application is carried out under head up (see user guide ) .

1. Remove the protective plug .
2 . Before use inflate several times
 
3 . Spray once in each nostril until a steady stream. keeping his head up .
4 . Clean nozzle and insert the protective plug .
 
 
Duration of treatment
Allergodil nasal spray can be used until symptoms have resolved , but it should not be continued without interruption for more than 6 consecutive months.
 
Overdose and other errors in use
What should be done in case of intentionally or accidentally overdose Allergodil nasal spray ?
Allergodil nasal spray is applied topically in the nose. Due to the small amount of drug , signs of overdose are not observed even in cases of excessive overdosage with topical administration. However, Accidental ingestion of large amounts of drug (eg the contents of one bottle of the child) must necessarily seek medical advice.
There are no empirical data on toxic ( very high, toxic ) doses of azelastine hydrochloride in humans. The results of animal experiments suggest that extreme overdose and intoxication ( poisoning ) cause symptoms of central nervous system ( eg, restlessness, anxiety or severe persistent fatigue or drowsiness ) . In these cases, treatment is simptimatichno .
 
What should you do if you apply a small amount Allergodil ® nasal spray or you miss an application ?
If you forget to Allergodil nasal spray does not require any special measures. Continue to use the same dose and timing of administration . If necessary, you can apply Allergodil ® nasal spray between two regular intake .
 
What should be done in case of discontinuation of Allergodil ® Nasal Spray ?
If possible , continue regular application of Allergodil ® Nasal Spray until symptoms . For pre discontinuation Allergodil nasal spray, typical symptoms of your illness may soon resume .
 
 
Undesirable effects
What side effects may occur during treatment with Allergodil nasal spray ?
In rare cases, as a result of injection may result in irritation of the already inflamed nasal mucosa , which may be manifested eg . as tingling, itching and sneezing. In rare cases can occur nosebleeds . There will be fatigue , weakness, fatigue, dizziness. By misuse ( head tilted back , see " Dosage , route and duration of administration " ) may appear bitter taste in the mouth, which can sometimes cause nausea .
If you notice any side effects not listed is this leaflet, please inform your doctor or pharmacist.
 
What steps you should take in the event of adverse reactions ?
These side effects are generally temporary and therefore do not need to take special measures.
If you feel a bitter taste in the mouth after administration of Allergodil nasal spray can neutralize it by adopting alkoholic drink (eg, juice, milk) .
 
 
Expiration date
3 years
The expiry date is indicated on the carton and the bottle label Allergodil nasal spray .
Do not use it after marking durability.
 
How long can be used Allergodil nasal spray after first opening the bottle?
Do not use more than 6 months after first opening the bottle.
 
 
In which cases should not be used Allergodil nasal spray, even before the expiration date ?
If Allergodil nasal spray inadvertently been stored under +8 ° C (e.g. in a refrigerator) for an extended period of time , the active substance begins to partially crystallize. This formation of crystals ( " flocculation " ) is visible if you look at the bottle against the light . This solution should not be used !
Upon further prolonged storage of the solution at room temperature ( for several hours) , crystals were dissolved completely . This clear solution (no visible flocculation ) can be used .
 
Special precautions for storage
Store at temperatures below 25 ° C.
Do not freeze !
Keep out of reach of children!