BANEOCIN 20g

Baneocin powder / ointment contains 1 g of Bacitracin Zinc: 250IUNeomycin 5000 IU ( 5 mg)
Excipients - ointment : lanolin , white soft paraffin
 
action
Baneocin is antibiotic combination for outdoor use. Contains two highly antibiotachni ingredients with synergistic deystvye - neomycin and batsitratsin.Batsitratsin is mainly active against gram-positive organisms including Streptococcus haemolyticus, Staphylococcus, Corynebacterium diphtheriae, Clostridia, Treponema pallidum and some Gram-negative pathogens such as Neisseria and Haemophilus influenzae. It is also active against Actinomyces and Fusobacteria. Resistance to bacitracin is extremely ryadka.Neomitsinat acts against both Gram-positive and Gram-negative pathogens against including staphylococci, Proteus, Enterobacter aerogenes, Klebsiella pneunoniae, Salmonella, Shigella, Haemophilus influenzae, Pasteurella, Neisseria meningitidis, Vibrio cholerae, Bordetella pertussis, Bacillus anthracis, Corynebacterium diphtheriae. Streptococcus faecaliis, Listeria monocytogenes, Escherichia coli, Mycobacterium tuberculosis. It is active against Borrelia and Leptospira interrogans (L. icterohemorrhagicae). Combined action of both antibiotics leads to a broad spectrum effect , which however does not affect Pseudomonas, Nocardia, and fungi and neomycin virusi.Batsitratsin not usually administered systemically . Topical administration of Baneocin- powder and ointment substantially reduces the risk of the possibility for potentiating their effects upon systemic administration of antibiotitsite.Baneocin tolerated . Its compatibility with the tissues is excellent and does not exhibit any inactivation of secretion , blood or tissue components . If the medicine is applied to the large wound surfaces of the skin , you should take into account the possibility of absorption and its consequences (see " Undesirable effects ", " Interaction ", " Contra ," " Special warnings and precautions for use " ) .
 
witness
Baneocin is effective to treat skin infections caused by sensitive to neomycin and / or bacitracin microorganisms.
Baneocin powder
- No large area bacterial infections of the skin , e. :
Herpes simplex, Herpes zoster / varicella vesicles, wet kompetigo contagious infected ulkus kruris infected eczema , bacterial dermatitis produced by infected diapers.
- Prevention of umbilical infections in infants.
- Sped surgery ( dermatologic ) procedures .
- Baneocin powder can be used as an adjuvant treatment during the postoperative recovery ( cuts, burns , perineal laceration , episiotomy , sores and scars ) .
Baneocin ointment
- Focal bacterial skin infections , e. :
Furuncles , carbuncles ( postoperative treatment ), folliculitis barbae, folliculitis profunda, suppurative hidradenitis, periporitis, paronychia.
- Low levels of surface bacterial infections of the skin such as :
Contagious impetigo , infected ulkus kruris , secondarily infected eczema, secondarily infected lacerations and cuts , burns, after cosmetic surgery and skin grafting (also for prophylactic use and bandages ) .
- After major and minor surgical procedures
- Baneocin ointment can be used as an adjuvant therapy during the post-operative recovery :
Baneocin ointment applied onto the gauze pad is useful for direct topical therapy in patients with infections of the body or outer pockets (e.g., infections of the outer ear canal , surgical wounds or scars that strengthen secondary ) . The effect of Baneocin ointment is supported by the use of dressing.
 
Method of administration :
Powder or ointment is applied in a thin layer over the area for treatment. The place can be covered with a bandage .
 
dosage
The doctor will determine the correct dosage, If not otherwise indicated in adults and children Baneocin powder is applied most often 2-4 times daily until Baneocin ointment is used 2-3 times a day. In patients with burns covering more than 20% of body surface , Baneocin powder should be administered once a day, particularly in patients with damaged kidneys , because the drugs can be absorbed in part and adversely deystvie.Pri topical administration Dose neomycin must not exceed 1 g per day (equivalent to 200 g powder , or ointment ) for 7 days. In the second course of treatment that maximum dose should be halved .
 
Contraindications
Known hypersensitivity to bacitracin and / or neomycin and other aminoglycoside antibiotics. Baneocin should not be used in severe extensive damage to the skin , since absorption can cause a loss of ototoxicity sluha.Baneocin should not be used in patients with severe disorders excretion of cardiac or renal origin , and after previous disease vestibular and / or the ear , if the absorbance can not be kontrolirana.Da not apply in the external ear canal to the tympanic membrane if the membrane is perforated . Baneocin not use in the eyes .
 
Pregnancy and lactation
If absorption Baneocin can not be controlled it must be used with caution in pregnant and lactating women. Like any other aminoglycoside antibiotics neomycin crosses the placenta. Systemic administration of high doses of aminoglycosides causes damage to the cochlea of the fetus.
 
Adverse reactions.
Applied in accordance with the warnings made Baneocin well tolerated. Patients undergoing treatment for a long time may develop allergic reactions such as redness and dryness of the skin, skin rash and sarbezh.Kogato is used to treat chronic dermatoses ( congestive dermatoses ) or chronic otitis Baneocin helps to increase the sensitivity to a variety of other drugs including neomycin. This can occur through poor treatment response . Allergy manifested as contact eczema is rare. Allergy to neomycin is less common . In about 50 % of the allergy due to the neomycin cross allergy to other aminoglycoside antibiotics. In patients with extensive skin lesions should be taken into account absorption Baneocin and consequences that can occur with damage to the vestibular system and hearing , nephrotoxicity and neuromuscular blockade.
 
Interactions ( due to systemic absorption )
In the case of systemic absorption concomitant administration of cephalosporins and aminoglycoside antibiotics other can enhance нефротоксичността.Едновременното acceptance of diuretics such as ethacrynic acid or furosemide may also aggravate oto- and nephrotoxicity . Patients receiving narcotic drugs , anesthetics or relaxants absorption Baneocin may potentiate the effect of neuromuscular blockade.
 
Incompatibilities
Baneocin is incompatible with products containing salicylic acid, tannin and heavy metals. Special warnings and precautions for upotreba.Ako administered dose exceeds the prescribed attention should be drawn to the possible nephro and / or ototoxicity due to absorption of Baneocin especially in patients with trophic ulcers.
In patients with damages of the liver or kidneys treated with intensive Baneocin must examine the urine , blood counts and hearing prior to and during treatment , because they can be expected toxic effects due to the reduced functions liver and kidneys. Caution should be exercised when administered to patients with chronic otitis due to the risk of occurrence of ototoxicity . Do not apply in the external ear canal if the tympanic membrane is perforated . Failing to control the absorption of Baneocin acidosis in patients with myasthenia gravis or other neuromuscular disorders should be considered a possible blockade , which can be controlled by the application of calcium or prolonged administration neostigmin.Pri special attention should be paid to the possibility of the development of resistant microorganisms and in particular fungi. In these cases should be given appropriate treatment. In patients with allergies or superinfection application of the product should be discontinued .
 
Stability and durability
Properly stored Baneocin powder / ointment remain fully active on the date indicated on the package.
 
Storage Conditions
Store at temperatures below 25 ° C, keep away from direct light. Keep the powder dry.
 
Formulation and packaging
Baneocin powder : pudrierar containing 10 gBaneocin ointment tubes of 20 g in single hospital opakovkiRegistrirana in Bulgaria formaDa Keep out of reach of children !