BENOXI  10 ml.

WHAT BENOXI UNIMED PHARMA AND WHAT IT IS USED
BENOXI UNIMED PHARMA is a medicine for ocular topical anesthetic. The active substance is oksibuprokainov hydrochloride - anesthetic synthetic ester type. BENOXI UNIMED PHARMA is an effective, superficial, short-acting anesthetic (narcotic) with a quick upward effect. It reversibly blocks the emergence and impulse conduction in sensory nerves, thereby causing temporary anesthesia (anesthesia) at the site of application. It is more effective than cocaine. BENOXI UNIMED PHARMA does not affect the width of the pupil and the ability to accommodate (to fix in sight).
BENOXI UNIMED PHARMA used for surface anesthesia of the cornea and the conjunctiva (the surface of the eye) during removal of superficial or deep-seated foreign bodies during tonometry (Measurement of intraocular pressure) gonioskopiya (measuring the angle of the anterior chamber of the eye), and other diagnostic procedures. In preparation for subconjunctival and retrobulbar injections.

2 BEFORE USING BENOXI UNIMED PHARMA
Do not use BENOXI UNIMED PHARMA:
if you are allergic (hypersensitive) to oxybuprocaine or any of the other ingredients of the product;
if you are allergic (hypersensitive) to other local anesthetics from the group of esters of parabens or local anesthetics of the amide type;
in children under two years of age;
in the presence of an infection
Take special care with BENOXI UNIMED PHARMA
BENOXI UNIMED PHARMA should be used with caution in patients with pseudocholinesterase deficiency, myasthenia gravis, low blood pressure, heart disease (heart failure, irregular heart beat) and epilepsy. Uncontrolled use of any anesthetic, even at low concentrations, may, after a short reception result in damage to the cornea. In cases of persistent pain, the patient should be prescribed systemic analgesics. Even a single application leads to ulceration of the soft surface of the cornea.
Since oxybuprocaine stops bacterial growth and reproduction (ie has a bacteriostatic effect) BENOXI UNIMED PHARMA should not be applied before taking a sample for bacterial culture.
Wearing contact lenses should shoot them down before applying this medicine and put them back after the complete disappearance of signs of anesthesia.
BENOXI UNIMED PHARMA should not be applied as simple drug.

Using other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
The effects of BENOXI UNIMED PHARMA and other drugs can be mixed when applied simultaneously.
BENOXI UNIMED PHARMA enhances the effects of succinylcholine and sympathomimetics, reduces the effects of sulfonamides and beta-blockers, is incompatible with solutions of fluorescein, as it contained a preservative chlorhexidine diacetate precipitate formed with them. The product is not compatible with the silver nitrate, mercury salts and other alkaline substances.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine. Implementation of BENOXI UNIMED PHARMA in pregnant and lactating women can be done only if the potential benefit to the mother outweighs the potential significant risk to the fetus or child.

Driving and using machines
Driving and operating machinery shall be allowed as early as one hour after application.

3 HOW TO USE BENOXI UNIMED PHARMA
This drug should be administered by a physician and can be used for a short time. During anesthesia, the patient should not touch the eye, it must be protected from dust and bacterial infections.
The eye drops are dropped into the conjunctival sac. Between single product dripping eyes should be closed. The exact dosage should always be determined by the physician.

The usual dose is:
Under anesthesia of the cornea and conjunctiva:
To remove surface located foreign body: 3 times a drop in the space of five minutes.
For removal of deep foreign body located from 5 to 10 times a drop in the range of 30 to 60 seconds.

Before subconjunctival or retrobulbar injection:
3 times a drop in the space of five minutes.

In tonometry, gonioskopiya and other procedures:
1-2 drops.

If you are given more than the amount BENOXI UNIMED PHARMA
When used as directed, overdose is practically excluded. Systemic toxic effects were predominantly of the central nervous system and the cardiovascular system: anxiety, insomnia, nausea, vomiting, muscle spasms, abnormal breathing, coma (unconscious), hypotension (low blood pressure), shock, cardiac arrest. If a child swallows more than the required dose or accidentally take this drug, seek immediate medical help.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4 POSSIBLE SIDE EFFECTS
Like all medicines, BENOXI UNIMED Pharma can cause side effects, although not everybody gets them.
Immediately after administration observed temporary burning and redness of the conjunctiva. Possible damage of the surface layer of corneal erosion and corneal ulceration. Can be observed effects like inflammation of the cornea and cataract, allergic reactions of the eyelids and conjunctiva.

Systemic effects due to absorption: allergic, cardiovascular reactions, anaphylactic shock (shock due to hypersensitivity of the body to foreign substances), syncope (temporary and brief loss of consciousness), toxicity of the central nervous system. The emergence of such systemic adverse reactions after administration of the preparation in the conjunctival sac is unlikely.

If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5 HOW TO STORE BENOXI UNIMED PHARMA
Do not store above 25 ° C.
Do not refrigerate.
Protect from light.
Keep out of reach of children.
Do not use BENOXI UNIMED PHARMA after the expiry date stated on the pack. Opened container can be used for 28 days after first opening.
After each application, close the bottle.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6 FURTHER INFORMATION
Contents BENOXI UNIMED PHARMA
The active substance is oksibuprokainov hydrochloride 4 mg / ml.
Other ingredients are: boric acid, chlorhexidine diacetate, purified water.

Looks BENOXI UNIMED PHARMA and contents of the pack
Bottle of 10 ml placed in a carton.
Bottle of 5 ml placed in a carton.