BI-Profenid 150 mg. 20 tablets

Qualitative and quantitative composition
Active substance: ketoprofen 150 mg per tablet
Excipients: White plastic, lactose, starch, hydrated silica, gelatin, magnesium stearate. Yellow layer - hydroxyethyl cellulose, calcium hydrogen phosphate, sodium riboflavin phosphate (E 101), magnesium stearate.
 
formulation
Double layer divisible modified-release tablets-pack of 20 tablets.
 
Pharmacotherapeutic group
NSAIDs (M: Musculoskeletal).

WHEN TO USE THIS DRUG (Therapeutic indications)
Medicinal product used in people over the age of 15, such as:
• continuous symptomatic treatment of:
- Chronic inflammatory rheumatism, especially rheumatoid arthritis, "ankylosing spondylitis (or related syndromes such as syndrome Fiessinger - Leroy - Reiter and psoriatic arthritis),
- Some forms of painful debilitating osteoarthritis.
• short-term symptomatic treatment of acute episodes of:
- Extraarticular rheumatism, as humero-scapular periarthritis, tendinitis and bursitis
- Microcrystalline arthritis
- Osteoarthritis,
- Pain in the lower back,
- radiculitis
 
WHEN NOT TO USE THIS DRUG (Contra)
Medicines should not be used in the following cases: hypersensitivity (allergy) to ketoprofen or any of the excipients, after 6 months of pregnancy; history of allergy or asthma due to this drug, or similar drugs, especially non-steroidal anti-inflammatory drugs including aspirin; active gastric ulcer or duodenal ulcer; severe liver disease; nekontruleruema severe heart failure; severe kidney disease; gastrointestinal bleeding, cerebrovascular bleeding or other bleeding. Persons under 15 years vazrast.Tozi medicinal product must not be administered to persons with srahchuvstvitelnost or intolerance to gluten because of wheat starch (gluten). If you are unsure, contact your doctor or farmatsevt.Spetsialni preduprezhdeniyaTova drug should only be taken under medical nablyudenie.Predi starting to use this medicine, tell your doctor in case of:
• previous related asthma, chronic rhinitis, chronic sinusitis or nasal polyps. The appointment of this drug can lead to respiratory sensitization or asthma crisis, especially in patients who are allergic to aspirin or other NSAIDs (see instructions).
• 'problems with blood clotting during concomitant anticoagulant or antiplatelet plaketaren.
• This medicine may cause serious gastrointestinal (GI) events.
• previous digestive problems (ulcers of the stomach or duodenum, colitis, Crohn's disease).
• previous (history) skin reactions when exposed to sunlight or ultraviolet lachi.e heart disease, liver or kidney.
• treatment with a diuretic or a recent surgery.
• because the drug contains lactose, it is contraindicated in patients with congenital galactosemia, syndrome or glucose-galactose malabsorption or lactase deficiency.
During treatment, in cases of:
• signs of infection, tell your doctor.
• signs of allergy to this medicine as asthmatic crisis, urticaria, severe swelling of the face and neck, stop treatment immediately and contact your doctor or hospital emergency department care.
• gastrointestinal haemorrhage (vomiting blood in the mouth, blood in stool or stool color black), stop treatment immediately and contact your doctor or hospital emergency department care. • If you know that you have an intolerance to some sugars, please tell your doctor before taking this medicine.
 
Warning for use
This medicine contains a non-steroidal anti-inflammatory drug: ketoprofen.Ne should not take this medication simultaneously with other drugs containing NSAIDs and / or directions carefully aspirin.Prochetete other medicines you are taking to make sure they do not contain other non-steroidal inflammatory and / iliaspirin.
Precautions for use
Due to the need for dose adjustment, it is important to tell your doctor that displays the recipe that you have a history of digestive disorders (previous gastric or duodenal); ulcerative colitis, heart, liver or kidney disease; asthma (in some patients, asthma attack may be due to an allergy to aspirin or nonsteroidal anti-inflammatory drug: in this case, this drug is contraindicated); use of an intrauterine contraceptive device. The use of ketoprofen is not recommended for women who are trying to conceive because of reversible inhibition of fertility. If you are unsure, contact your doctor or pharmacist.
 
Interactions with other medicaments and other forms of interaction
To avoid possible interactions with other drugs, especially other NSAIDs, including aspirin in high doses, oral contraceptives, heparin, lithium, ticlopidine, methotrexate, pentoxifylline, diuretics, zidovudine, you should tell your doctor or pharmacist about any treatment which conduct the same time.
 
Pregnancy and lactation
In case of pregnancy and lactation, you should always consult your doctor for advice before you start treatment.
- Pregnancy:
during the first 5 months of pregnancy, your doctor may decide to prescribe this medication as necessary. Six months of pregnancy, UNDER NO CIRCUMSTANCES SHOULD NOT TAKE THIS MEDICINE OF YOUR OWN, as the effects on your unborn baby can lead to serious consequences for renal and cardio-pulmonary nature, even in a single dose, even when the baby is of the term.
- Lactation:
this medicine passes into breast milk. As a precaution, should be avoided by nursing mothers.
Driving and using machines in rare cases, use of this drug may cause dizziness and drowsiness, seizures or visual impairment. If any of these symptoms occur, you should not drive or operate machinery.
 
HOW TO USE THIS MEDICINE
dosage
1 to 2 tablets dnevno.Tabletkata be swallowed whole (not chewed) with a glass of water during hranene.Dnevnata dose should be taken 1 or 2 priema.Pri all cases, strictly follow the doctor's prescription.
Duration of treatment
In all cases, strictly follow the doctor's prescription. Action in predoziranePri overdose intentional or accidental intoskikatsiya, immediately contact a doctor.
 
Undesirable effects
As a medicinal product, this drug may result in more or less side effects. During treatment may occur: Skin allergic reactions: skin rash, itching, hives worsening of chronic urticaria, photosensitivity (severe skin reactions due to exposure to the sun or ultraviolet radiation).
- Respiratory allergic reactions: asthmatic attacks or general type: rarely angioedema (type of urticaria with sudden infiltration of the face and mucous fluid) and anaphylactic shock.
- Exceptionally, bullous lesions (blisters type) throughout the body, and sometimes mucous membranes. You should stop the treatment and tell your doctor.
- In some rare cases: bleeding from the digestive tract (discharge of blood in the mouth or in the stool, black stools). It is more common with use of high doses. You should stop the treatment and tell your doctor.
- Possible gastrointestinal disorders: nausea, vomiting, diarrhea, constipation, abdominal pain, gastrointestinal discomfort; headache, dizziness, drowsiness, tinnitus, visual disturbances, edema, weight gain, changes in taste. You should tell your doctor.
- Observed rare cases of gastrointestinal ulceration and perforation and exceptional cases of hepatitis.
- Some changes in laboratory values may necessitate blood, kidney or liver tests:
• impairment of renal function in case of preexisting disorder.
• In exceptional cases an abnormally low number of certain elements of the blood can be expressed with pallor and fatigue (abnormally low number of chervenitekravni cells), signs of infection or unexplained fever without serious consequences (abnormally low number of white blood cells). • Very frequent violations of liver function that are transient and obratimi.Ne hesitate to contact your doctor or pharmacist for advice and to report any side effects not listed in this leaflet.
 
STORAGE
Do not use after the expiry date stated on the outer opakovka.Da Keep out of reach of detsaSpetsialni conditions sahranenieDa stored at temperatures below 25 C. Protect from light and moisture.