BRIEKA 150 mg. 60 capsules

What is Brieka and what it is used
Brieka belongs to a group of medicines used to treat epilepsy, neuropathic pain and generalized anxiety disorder (GAD) in adults.

Peripheral and central neuropathic pain:
Brieka be used for the treatment of persistent pain caused by nerve damage. Different diseases can cause peripheral neuropathic pain, such as diabetes or shingles. Pain sensations may be described as hot, burning, throbbing, shooting, stabbing, sharp, like cramps, with severe pain, stinging, numbness, tingling. Peripheral and central neuropathic pain may be associated with mood changes, sleep disturbances, fatigue (weakness) and can affect the physical and social activity and quality of life in general.

epilepsy:
Brieka used to treat some forms of epilepsy (partial seizures with or without secondary generalization) in adults. Your doctor will prescribe Brieka to help you treat your epilepsy when your current treatment is not controlling your condition. You should take Brieka addition to your current treatment. Brieka is not intended for private use and should always be used in combination with other antiepileptic treatment.

Generalised Anxiety Disorder:
Brieka used to treat generalized anxiety disorder (GAD). Symptoms of GAD are prolonged, very pronounced fear and anxiety, which are difficult to control. GAD can also cause restlessness or feeling agitated or instability, tiredness (fatigue), having difficulty concentrating or inability to think, to feel irritable, having muscle tension or sleep problems. This is different from the stress and strains of everyday life.

2. What you need to know before taking Brieka
Do not take Brieka:
if you are allergic to pregabalin or any of the other ingredients of this medicine (listed in section 6).
Warnings and Precautions
Talk to your doctor or pharmacist before taking Brieka:
Some patients taking Brieka, reported symptoms suggestive of allergic reaction. These symptoms are: swelling of the face, lips, tongue and throat, as well as diffuse skin rash. If any of these reactions, you should immediately contact your doctor;
The use of Brieka been associated with dizziness and somnolence, which could increase the occurrence of accidental injury accidents (fall) in elderly patients. Therefore, you should be careful until you get used to any effect that drug can have;
Brieka may cause blurring or loss of vision or other vision changes, many of which are temporary. You should immediately contact your doctor if you experience changes in vision;
Some patients with diabetes, which increase the weight while taking pregabalin may require a change in medication for treating diabetes;
Certain side effects, such as somnolence, can be more common, because patients with spinal cord injury may be taking other drugs (for example for the treatment of pain or cramps), which have similar side effects, such as pregabalin and the severity of these effects may be increased when co-administered;
In some patients taking Brieka there are reports of heart failure. These patients were mostly elderly with cardiovascular disease. Before taking this medication, tell your doctor if you have a history of heart disease;
In some patients taking Brieka there have been reports of renal insufficiency. If you notice decreased urination while taking Brieka should tell your doctor as stopping the medicine may improve this situation;
A small number of people being treated with antiepileptic medications, such Brieka have had thoughts of harming or killing themselves. If you have these thoughts, immediately contact your doctor;
Brieka when taken with other drugs that can cause constipation (such as some types of pain) may occur some gastrointestinal problems (eg. Constipation, blockage or paralysis of the bowel). Tell your doctor if you experience constipation, especially if you are prone to this problem;
Before taking this medicine you should tell your doctor if you suffer from alcoholism or any drug abuse or dependence. Do not take more medicine than what has been prescribed;
There have been reports of convulsions when taking Brieka or immediately after discontinuation of Brieka. If you get a cramp, immediately contact your doctor;
In some patients taking Brieka who suffer from other illnesses have been reported impairment of brain function (encephalopathy). Tell your doctor if you have a history of any serious diseases, including liver or kidney disease.
Children and adolescents
Safety and efficacy in children and adolescents (under 18 years) have not been established and therefore, pregabalin should not be used in this age group.

Other medicines and Brieka
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Brieka and certain other medicines can affect each other (interaction). When taken with certain other medicines Brieka may intensify the side effects seen with these medicines, including respiratory failure and coma. The degree of dizziness, sleepiness and decreased concentration may be increased if Brieka be taken with medicines that contain:
Oxycodone - (used as anesthetic);
Lorazepam - (used for the treatment of anxiety);
Alcohol.
Brieka can be taken concurrently with contraceptives that are taken orally.

Brieka with food, drinks and alcohol
Brieka capsules can be taken with or without food.
It is recommended to not use alcohol while taking Brieka.

Pregnancy and lactation
Brieka should not be taken during pregnancy or when breast-feeding, unless your doctor tells you otherwise. Women of childbearing potential should use effective contraception. If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.

Driving and using machines
Brieka can cause dizziness, sleepiness and decreased concentration. You should not drive, operate complex machinery or engage in other potentially dangerous activities until you know whether this medication affects your ability to perform these activities.

3. How to take Brieka
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Your doctor will determine what dose is appropriate for you.
Brieka is intended for oral (by mouth).

Peripheral and central neuropathic pain, epilepsy and generalized anxiety disorder:
Accept capsules as advised by your doctor.
The dose for you and your condition, will generally be between 150 mg and 600 mg daily.
Your doctor will tell you to take Brieka or two or three times a day. For twice a day take Brieka once in the morning and once in the evening, at about the same time each day. In tid take Brieka once in the morning, once in the afternoon and once in the evening, at about the same time each day.
If you feel that the effect of Brieka is too strong or too weak, talk to your doctor or pharmacist.
If you are an elderly patient (over 65 years) should not take Brieka normally except if you have kidney problems.
Your doctor may prescribe a different dosing schedule and / or dose if you have kidney problems.
Swallow the capsules whole with water.
Continue taking Brieka until your doctor tells you to stop.

If you take more than the amount Brieka
Immediately call your doctor or the nearest hospital emergency room. Take your box or bottle of capsules Brieka you. You may feel drowsiness, confusion, agitation or anxiety as a result of taking more than the amount Brieka.

If you forget to take Brieka
It is important to take your Brieka capsules regularly at the same time each day. If you forget to take a dose, take it as soon as you remember unless it is time for your next dose. In that case, just carry on with the next dose as usual. Do not take a double dose to make up the missed dose.

If you stop taking Brieka
Do not stop taking Brieka unless your doctor tells you to do this. Discontinuation of treatment should be done gradually for at least 1 week. You should know that after stopping long-term or short-term treatment with Brieka may experience certain side effects, such as sleep problems, headaches, nausea, feelings of anxiety, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, increased sweating and dizziness. These symptoms may occur more often or be more severe if you have taken Brieka for a longer period of time.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you get swelling of the face or tongue or if your skin is red and begin to appear blistering or peeling, you should seek immediate medical advice.

Very common (may affect more than 1 in 10 patients):
Dizziness, drowsiness, headache.
Common (may affect up to 1 in 10 patients):
Increased appetite;
Feelings of elation, confusion, disorientation, decreased sexual interest, irritability;
Disturbance in attention, clumsiness, memory impairment, memory loss, tremors, difficulty speaking, tingling, numbness, lethargy, lethargy, insomnia, fatigue, abnormal sensation;
Blurred vision, double vision;
Dizziness, problems with balance, fall;
Dry mouth, constipation, vomiting, flatulence, diarrhea, nausea, bloating;
Erection difficulties;
Swelling of the body, including the extremities;
Inebriation, impaired gait;
Weight gain;
Muscle cramps, joint pain, back pain, pain in extremity;
Sore throat.
Uncommon (may affect up to 1 in 100 patients):
Loss of appetite, weight loss, low blood sugar, high blood sugar;
Changes in self-perception, anxiety, depression, agitation, mood swings, difficulty finding words, hallucinations, abnormal dreams, panic attacks, apathy, aggression, elevated mood, mental impairment, difficulty thinking, increased sexual interest, problems with sexual function including inability to achieve orgasm, delayed ejaculation;
Changes in vision, abnormal eye movements, changes in the field, including tunnel vision, flashes of light, sudden movements, depressed reflexes, increased activity, dizziness on standing, increased skin sensitivity, loss of taste, burning sensation, tremor movement, depressed level of consciousness, loss of consciousness, fainting, increased sensitivity to noise, malaise;
Dry eyes, eye swelling, eye pain, eye fatigue, tearing, eye irritation;
Abnormal heart rhythm, increased heart rate, low blood pressure, high blood pressure, changes in heart rhythm, heart failure;
Flushing, hot flush;
Difficulty breathing, dry nose, nasal congestion;
Increased production of saliva, heartburn, numbness around the mouth;
Increased sweating, rash, chills, fever;
Muscle twitching, joint swelling, muscle stiffness, pain, including muscle pain, neck pain;
Chest pain;
Difficult or painful urination, urinary incontinence;
Weakness, thirst, chest tightness;
Changes in the results of blood and liver tests (increased blood creatine phosphokinase, increased alanine aminotransferase, increased aspartate aminotransferase, decreased platelet count, neutropenia, increased blood creatinine, increased blood potassium);
Hypersensitivity, facial swelling, itching, hives, runny nose, nosebleeds, coughing, snoring;
Painful menstruation;
Cold hands and feet.
Rare (may affect up to 1 in 1000 patients):
Altered sense of smell, unstable vision, altered depth perception, visual brightness, loss of vision;
Dilated pupils, strabismus;
Cold sweat, throat tightness, swelling of the tongue;
Inflammation of the pancreas;
Difficulty swallowing;
Slow or restricted movement of the body;
Difficulty in writing;
Increased amount of fluid in the abdomen;
Fluid in the lungs;
seizures;
Changes in recording electrical changes in the heart (ECG), corresponding to heart rhythm disturbances;
Muscle damage;
Breast discharge, abnormal breast enlargement, breast enlargement in men;
Disruption of the menstrual cycle;
Renal failure, decreased urine, urinary retention;
Reducing the number of white blood cells;
Irrational behavior;
Allergic reactions (which may be shortness of breath, inflammation of the eye (keratitis), and severe skin reaction, characterized by rash, blisters, skin peeling and pain);
Some side effects such as somnolence, can be more common, because patients with spinal cord injury may be taking other drugs to treat (e.g., pain or cramps), which have similar side effects, such as pregabalin and the severity of these effects may be increased when co-administered.

By reporting side effects, you can do your bit for getting more information on the safety of this medicine.

5. How to store Brieka
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton, blister or bottle after "EXP". The expiry date refers to the last day of that month.
Do not store above 30 ° C.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer are you required. These measures will help to protect the environment.

6. Contents of the pack and other information
What Brieka
The active substance is pregabalin. Each capsule contains 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg or 300 mg of pregabalin.
The other ingredients are mannitol, starch, a mixture (pregelatinized starch and corn starch), talc, gelatin, titanium dioxide (E171) and black ink (which contains shellac, black iron oxide (E 172), potassium hydroxide). Capsules of 75 mg, 100 mg, 200 mg, 225 mg and 300 mg also contain red ferric oxide (E 172).