Brimonidine eye drops 2mg. / Ml. 5 ml.

WHAT  Brimonidine Tartrate 0.2% eye drops SOLUTION AND WHAT IT IS USED 
This medicine is an eye drop which is used to control glaucoma. It comprises brimonidine, which reduces the high pressure in the eye, and belongs to the group of drugs called alpha-2 adrenergic receptor agonists.
Brimonidine is prescribed in order to reduce the high pressure in the eye when the eye drops containing beta-blockers can not be used or where appropriate a second drug for reducing pressure in the eye to a desired level.
Your eye contains a clear watery liquid that feeds the eye inside. The liquid was drained out of the eye continuously and replaced by new liquid. If the fluid can not drain fast enough, pressure inside the eye increases and this could gradually impair your vision. Brimonidine works by reducing the production of fluid, and increasing the amount of liquid to be drained. This reduces pressure in the eye while continuing to feed the eye.

2 Before applying TEVA Brimonidine Tartrate 0.2% eye drops SOLUTION
Do not use Brimonidine Tartrate Teva 0.2% eye drops, solution:
if you are allergic (hypersensitive) to brimonidine or any of the other ingredients of this medicine;
if the patient is under the age of two;
if you are taking monoamine oxidase inhibitors (MAOIs) or other antidepressants.
Take special care with this medicine
Before using this medication, tell your doctor:
If you have or have had in the past:
depression or other mental health problems;
heart problems or blood pressure;
reduced or impaired blood supply that affects the brain, lower or upper extremities;
kidney or liver problems;
If you wear contact lenses. Do not put the drops while wearing lenses. Wait at least 15 minutes after placing the drops before reinserting the lenses. The preservative in this drug called benzalkonium chloride can cause irritation of the eye, and it is also known to alter the color or discolour soft contact lenses.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine. Tell your doctor if you are pregnant or plan to become pregnant. This medicine should not be used during pregnancy unless your doctor still recommends it.
This medicine should not be used if you are breastfeeding.

Driving and using machines
This medicine may cause drowsiness, fatigue or blurred vision in some patients. Do not drive or operate machinery while such symptoms persist. If you have any problems, talk to your doctor.

Important information about some of the ingredients of this medicine
This medicine contains 0,05 mg / ml / benzalkonium chloride: see "Take special care with this medicine."

3 HOW TO USE TEVA Brimonidine Tartrate 0.2% eye drops SOLUTION
Always use Brimonidine Tartrate Teva 0.2% eye drops solution exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Ocular.
The usual dose is one drop of this medication twice daily for about 12 hours. Do not change the dose or stop taking the drug without first talking to your doctor.
If you are using this medication along with other eye drops, leave at least five minutes between Brimonidine Tartrate Teva 0.2% eye drops solution and other drops.

Instructions for use
You should not use the bottle if the tamper-proof seal on the bottle neck is broken before using it for the first time.
Wash your hands before opening the bottle.
Tilt your head back and look at the ceiling.
1 Gently pull down the lower eyelid until there is a small pocket.
2 Turn the bottle down and squeeze to release one drop in each eye that needs treatment.
3 Release the lower eyelid and close your eye.
4 Keep the eye closed and press a finger corner of the eye (the place where the eye meets the nose) for one minute.
If you can not put a drop in the eye, try again.
To prevent infection, do not let the tip of the bottle touch your eye or any other place. Insert the screw again to close the bottle immediately after use.

Children under 12 years of age and babies
Brimonidine is not recommended for use in patients under 12 years of age, and should not be used in infants and children younger than 2 years old.

If you use more than the amount of Brimonidine Tartrate Teva 0.2% eye drops solution
adults
If you use more of this medication than is necessary, it is very unlikely to cause any harm. Put the next drop of the usual time. If you are worried, talk to your doctor or pharmacist. If you swallow this medicine then you should call your doctor.

Baby
In infants (up to 4 weeks of age) who were administered brimonidine a few cases of overdose. Signs include drowsiness, lethargy, low body temperature and breathing difficulties.
If you develop any of these symptoms, call your doctor.

If you forget to use Brimonidine Tartrate Teva 0.2% eye drops solution
If you forget to use your medicine, apply one drop in each eye that needs treatment as soon as possible after they remember and return to normal rhythm. Do not take a double dose to make up for a missed dose.

If you stop using Brimonidine Tartrate Teva 0.2% eye drops solution
To work properly, you must use Brimonidine Tartrate Teva 0.2 percent every day.
Do not stop using your medicine unless your doctor tells you to do so.

4 POSSIBLE SIDE EFFECTS
Like all medicines, Brimonidine tartrate 0.2% Teva can cause side effects, although not everybody gets them.

Very common (affects more than 1 user in 10):
Eye irritation and allergic reactions in the eye, eye redness, burning, stinging, itching, foreign body in the eye, white spots under eyelid, blurred vision;
Headache, drowsiness;
Dry mouth;
Tiredness.
Common (affects less than 1 user in 10 but more than 1 person in 100):
Inflammation around the eye, swelling, redness and inflammation, or under the eyelid, sticky or painful eyes, tears, sensitivity to light, small lesions on the surface of the eye, dry eye, pale eyelids, vision problems;
Dizziness, taste disturbance;
Cold-like symptoms;
Digestive problems;
Weakness.
Uncommon (affects less than 1 person in 100 but more than 1 user in 1000):
Common allergic reactions;
depression;
Palpitations, effects on heart rate;
Dry nose.
Rare (affects less than 1 user in 1000, but more than 1 user in 10,000):
Shortness of breath.
Very rare (affects less than 1 user in 10,000):
Inflammation of the eye or reduce the size of the pupil;
insomnia;
fainting;
High or low blood pressure.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5 HOW TO STORE TEVA Brimonidine Tartrate 0.2% eye drops SOLUTION
Keep out of reach of children.
Do not use Brimonidine Tartrate Teva 0.2% eye drops solution after the expiry date stated on the carton and bottle. The expiry date refers to the last day of that month.
Do not store above 25 ° C.
Do not refrigerate or freeze.
Discard the bottle 28 days after opening, even if there is solution remaining.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6 FURTHER INFORMATION
What does this medicine:
The active substance is brimonidine tartrate (brimonidine tartrate). One milliliter of solution contains 2,0 mg brimonidine tartrate equivalent to 1,3 mg brimonidine.
Other ingredients are: benzalkonium chloride solution 50%, polyvinyl alcohol, sodium citrate, citric acid monohydrate, sodium chloride, water for injection and sodium hydroxide or hydrochloric acid to adjust pH.

How does this medicine and contents of the pack
Eye drops, solution
A clear, greenish solution in 5 ml plastic bottle with screw cap.
Pack sizes: 1.3 to 6 bottles. Not all pack sizes may be marketed.