CERVARIX amp. 1 vaccine

What Cervarix and what it is used?
 
Tservariks is a vaccine intended to protect females against the diseases caused by infection with human papilloma virus / HPV /
These diseases include :
- Cervical cancer
- Precancerous cervical lesions

The types of human papilloma virus contained in the vaccine / HPV types 16 and 18 / are responsible for approximately 70% of cancers of the cervix. Other HPV types can also cause a cancer of the cervix . Tservariks s Everything does not protect against HPV types .

When a woman is vaccinated with Tservariks , Immune system produces antibodies against HPV types 16 and 18. In clinical trials, that Cervirix preventing diseases associated with HPV in women aged 15-25 years. Tservariks also stimulates production en antibodies in females aged 9-14 years.

Cervarix not infectious and , therefore, can not cause the diseases associated with HPV.
Cervarix not be used for the treatment of HPV-associated diseases , which are already present at the time of vaccination .
Cervarix must be used in accordance with official guidelines.

Before you are given Cervarix :
 
Tservariks shall not apply if the person to be vaccinated:
- Is allergic to any of the active substances or to any of the ingredients of Tservariks . Priznatsiet of an allergic reaction may include itchy skin rash, shortness of breath and swelling of the face or tongue.
- There is a severe infection with a high temperature. In this case, it may be necessary to postpone the vaccination until recovery. A minor infection such as a cold should not be a problem , but talk to the doctor .

Take special care with Cervarix :
 
You should inform your doctor if the person to be vaccinated:
- There are problems with bleeding , or bruises easily
- A disease which reduces her resistance to infection , such as HPV infection

Tservariks not protect against diseases caused by infection with NPV types 16 or 18 if they are already infected with human papillomavirus types 16 or 18 at the time of vaccination .
Although vaccination may protect you from cancer of the cervix , it does not substitute for regular cervical screening. You should continue to follow your doctor's advice regarding smear cervical / Pap tests and preventative and protective measures.

Appropriate precautions against exposure to HPV and sexually transmitted diseases should continue as Tservariks not protect against all types of Human Papillomavirus .

Tservariks not protect against other diseases that are caused by human papilloma virus.
It is currently not known duration of protection after vaccination . In clinical trials in women aged 15 to 25 years has seen continuous protection up to 6.4 years after the first dose. The need for a booster dose has not been studied.

Taking other medicines:
 
Tservariks may be used with a combined booster vaccine comprising diphtheria , tetanus and pertussis components with or without inactivated polio or combined hepatitis A and hepatitis B vaccine or the hepatitis B vaccine , a separate injection site during the same visit .
The effect of Tservariks may not be optimal if used with medicines that suppress the immune system.

In clinical trials, oral contraceptives reduce the protection obtained with Tservariks .
Please inform the doctor if the person to be vaccinated is taking or have recently taken any other medicines, including medicines obtained without a prescription or has recently received any other vaccine .

Pregnancy and lactation :
 
Data on the use of Tservariks during pregnancy are not enough. If pregnancy occurs during the course of vaccination , you should consult your doctor.
It is recommended to postpone vaccination until the end of pregnancy.
Seek advice to your doctor about breast-feeding before you are given Tservariks .

Driving and using machines:
 
No information on the effect of Tservariks on your ability to drive or operate machinery.

How to use Cervarix ?
 
Doctor or nurse will administer Tservariks as an injection into the muscle of the upper arm .
Tservariks is designed for women aged over 9 years. Your doctor or nurse will administer three injections according to the following schedule:
 

First injection : at chosen date
Second injection : 1 month after the first injection
Third injection : 6 months after the first injection.

If necessary, the vaccination may be more flexible. Please consult your doctor for more information.

When Tservariks is given for the first dose , recommended Tservariks be given for the complete vaccination course of 3 doses.
 
The vaccine should never be given into a vein.
 

If you miss a visit next dose Cervarix :
 
It is important to follow your doctor or nurse regarding return visits. If you forget to visit your doctor at the scheduled time of vaccination , contact your doctor for advice.

If you do not complete the full course of vaccination consists of three injections , you may not get the best response and protection from the vaccination .

Possible side effects :
 
Very common - pain or discomfort at the injection site , redness or swelling at the injection site , headache , pain, tenderness or weakness , fatigue

Common - symptoms of gastrointestinal , including nausea , vomiting, diarrhea and abdominal pain , itching, red skin rash , hives , joint pain , fever

Uncommon - infections of the upper respiratory tract , dizziness, other reactions at the injection site such as hard lump, tingling or numbness

Adverse events reported post-marketing in Cervarix include:
 
- Allergic reactions. They can be recognized by: itchy rash on the hands and feet , swelling of the eyes and face, difficulty in breathing or swallowing, a sudden drop in blood pressure and loss of consciousness
These reactions usually occur before leaving the doctor's surgery . However, if your child is experiencing any of these symptoms should contact a doctor urgently , .
- Swollen lymph nodes in the neck, armpit or groin
- Fainting sometimes accompanied by shaking or stiffness.

How to store Cervarix ?
 
Keep out of reach of children.
Tservariks not use after the expiry date stated on the carton. The expiry date refers to the last day of that month.

Store in refrigerator. Do not freeze . Store in the original package to protect from light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.


Additional information:
 
What does Cervarix :
 
The active substances are :
Human papillomavirus type 1 16 L1 protein 2,3,4 - 20 micrograms
Human papillomavirus type 18 1 L1 protein 2,3,4 - 20 micrograms
1 Human Papillomavirus = HPV

2 adjuvant AS04, comprising:
3-O- desacyl - 4 - monophosphoryl lipid A / MPL / 3-50 micrograms

3 adsorbed onto aluminum hydroxide, hydrated / Al (OH) 3 / total 0.5 mg Al3 +

4L1 protein neinfiktsiozni form of virus-like particles produced by recombinant DNA technology using a Baculovirus expression system using Hi- 5 Rix4446 cells derived from Trichoplusia ni insect

The other ingredients are sodium chloride , sodium dihydrogen phosphate dihydrate and water for injection.