Clonarex 2 mg. 30 tablets

What Clonarex is and what it is used for
Clonarex contains a medicine called clonazepam. It belongs to a group of medicines called benzodiazepines.
Clonarex is used to treat epilepsy in infants, children and adults.
Clonarex reduces the number of seizures you receive.
If you get a fainting, it will not be so serious.

2. What you need to know before you take Clonarax
Do not take Clonarx if you are allergic (hypersensitive) to:

Clonazepam or any of the other ingredients of this medicine (listed in section 6);
Other drugs in the benzodiazepine group. These include diazepam, flurazepam and temazepam.
Do not take Clonarex if:

You have problems with breathing or pulmonary disease;
You have severe liver disease;
You have a disease called myasthenia gravis (where your muscles weaken and easily get tired;
You have a condition called sleep apnea (where your breathing stops during sleep);
You have problems with alcohol or medicines (taken on prescription or on your own initiative).
Do not take Clonarax if any of these apply to you. If you are not sure, talk to your doctor or pharmacist before taking Clonarax.

Warnings and precautions
A small number of people treated with anti-epileptic drugs such as clonazepam have thoughts of self-harm or suicide. If at any given time such thoughts occur, contact your doctor immediately.

Talk to your doctor or pharmacist before taking Clonarex:

If you have problems with the liver, kidneys or lungs;
If you have ever had depression;
If you have attempted suicide;
If a friend or close person has recently died;
If you regularly consume alcohol or take drugs or have had problems with the use of alcohol or medicines in the past;
If you have spinal or cerebellar ataxia (a condition where movements may become uncertain and unstable, speech is unclear or rapid eye movements occur);
If you have a rare, innate blood problem called porphyria;
If you are over 65 years of age or your body has become weak due to a severe and / or prolonged illness, your doctor may need to adjust your dose.
If any of the above applies to you or you are not sure, talk to your doctor or pharmacist before taking Clonarax.

Other medicines and Clonarex
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes both medicines you bought without a prescription, as well as herbal medicines. This is because Clonarax may affect the action of some other medicines. Also, some other medicines may affect the action of Clonarax.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

Other medicines for the treatment of epilepsy, such as carbamazepine, hydantoin derivatives, phenobarbital, phenytoin, primidone or sodium valproate;
Cimetidine (used to treat stomach problems and heartburn);
Rifampicin (an antibiotic used to treat infections);
Drugs used for sleeping (sleeping);
Anxiety medications (tranquilizers);
Painkillers (analgesics) and muscle relaxants (muscle relaxants).
Operations
If you are going to have anesthesia (anesthesia) for surgery or dental treatment, it is important to tell your doctor or dentist that you are taking Clonarax.

Clonarex with alcohol
Do not consume alcohol while taking Clonarax. This is because Clonarax can cause side effects or resumption of epileptic seizures.

Pregnancy, breastfeeding and fertility
Do not take Clonarex if you are pregnant, think you may be pregnant or are breast-feeding unless your doctor advises you. This is because Clonarax can cause damage to the fetus or baby.

Driving and using machines
Ask your doctor about driving and using machines while taking Clonarax. This is necessary because Clonarex may slow your reactions, especially when you start taking it. Talk to your doctor if you have a doubt as to whether you can do a certain activity.

Dependence
When taking this medicine, there is a risk of addiction, which increases with an increase in the dose and duration of treatment, as well as in patients with a history of alcohol and / or drug abuse.

Clonarex 0.5 mg tablets contain sunset yellow FCF (E110)
The sunset yellow FCF (E110) may cause allergic reactions.

3. How to take Clonarex
Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor.

Application method

Your doctor will start your treatment with a low dose of Clonarax, which will gradually increase for 2 to 4 weeks until the right dose is reached.
Usually, your doctor will treat you
Elderly:
The usual starting dose is 0.5 mg daily or less.
The starting dose will be gradually increased (usually up to 4 mg - 8 mg daily). The maximum dose is 20 mg per day.

Infants (0 to 1 year):
The usual starting dose is 0.25 mg daily or less.
The starting dose will be gradually increased (usually up to 0.5 mg - 1 mg daily).

Small children (1 to 5 years old):
The usual starting dose is 0.25 mg daily or less.
The starting dose will be gradually increased (usually up to 1 mg - 3 mg per day).

Older children (5 to 12 years old):
The usual starting dose is 0.5 mg daily or less.
The starting dose will be gradually increased (usually up to 3 mg - 6 mg daily).

If you take more Clonarax than you should
If you take more Clonarex than you should, or someone else has accidentally taken your Clonarx tablets, contact your doctor or go to the hospital immediately. Take the medicine pack with you.
If you take too many tablets, you may feel drowsiness, tiredness, dizziness, impaired coordination of movements, weakness or no reaction.

If you forget to take Clonarex
If you miss a dose, skip the missed dose and take the next dose at the usual time.
Do not take a double dose (two doses at the same time) to make up for the missed dose.

If you stop taking Clonarax
If you are being treated for long periods of time with Clonarax (you take the medicine for a long time), you may become dependent on it and get withdrawal symptoms (see section 4, "Possible side effects").
Do not stop taking the tablets without consulting your doctor. If you do, seizures may recur and you may experience withdrawal symptoms (see section 4).
If the dose of Clonarax you are taking should be reduced or stopped, this should be done gradually. Your doctor will advise you on how to do this.

If someone accidentally takes your Clonarx tablets, you should immediately consult a doctor or go straight to a hospital.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.

Serious undesirable effects to be monitored
Allergic reactions:
If you get an allergic reaction, contact your doctor immediately.
Symptoms may include:

Sudden swelling of the throat, face, lips and mouth. This may cause difficulty in breathing or swallowing;
Sudden swelling of the hands, feet and ankles;
Skin rash or itching.
Side effects from the heart:
If you notice any of the following side effects, talk to your doctor straight away.
Symptoms may include:

Shortness of breath, swelling of the ankles, cough, fatigue and palpitations;
Chest pain that can spread to the neck, shoulders and left hand.
Side effects related to behavior:
Talk to your doctor if you notice any of the following side effects, as you may need to stop taking Clonarax.
Symptoms may include:

Aggression, agitation, irritability, nervousness or anxiety;
Sleep problems, nightmares and vivid dreams;
Psychic problems such as seeing or hearing things that are not real (hallucinations), delusions (belief in things that are not real), and speech problems;
Types of seizures (convulsions) you did not have before.
Adverse reactions in children and adolescents

Infants and young children who receive Clonarex should be monitored very carefully. This is because they may experience breathing problems, coughing or choking. This may be caused by the release of too much saliva;
Early puberty in children. It is reversible after stopping treatment with Clonarax.
Other possible side effects
When you start taking Clonarx, you may notice the following side effects:

Drowsiness and fatigue;
Dizziness and fainting;
Weakness or relaxation of the muscles or abrupt movements (impaired coordination);
Walking instability.
If you notice any of these side effects, talk to your doctor. Your doctor may help by prescribing a lower dose of Clonarex and then slowly increasing it.

The following side effects may occur at any time during treatment with Clonarax:
Psychiatric disorders and nervous system disorders:

Disturbed concentration, confusion and disorientation;
Anxiety;
Difficulty in remembering new things;
Headache;
Depression;
Delay or rush of speech;
Distorted coordination, including a sense of walking instability;
Increase the frequency of seizures you receive.
Renal, liver and blood disorders:

Hepatic impairment (found in blood tests);
Urinary discharge;
Blood problems. Symptoms include fatigue, bruising
Symptoms may include:

Sleep problems;
Muscle pain, tremor (tremor) and anxiety;
Strong anxiety, tension, confusion, irritability or excitement, or mood swings;
Increased sweating;
Headache.
Less common withdrawal symptoms include:

Sensitivity to light, noise and physical contact;
Seeing or hearing things that are not real (hallucinations);
Numbness and stiffness of the hands and feet;
A sense of loss of contact with reality.

How to store Clonarex
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.

6. Package Contents and Additional Information
What Clonarex contains
The active substance is clonazepam.
Each Clonarex 0.5 mg tablet contains 0.5 mg of clonazepam.
Each Clonarex 2 mg tablet contains 2 mg of clonazepam.

The other ingredients are:
For 0.5 mg: Pulp, microcrystalline, povidone, sodium starch glycolate, starch, pregelatinised, silica, colloidal anhydrous, magnesium stearate, sunset yellow E110.
For 2 mg: Pulp, microcrystalline, povidone, sodium starch glycolate, starch, pregelatinised, colloidal anhydrous silica, magnesium stearate.

What Clonarex looks like and contents of the pack
Clonarex 0.5 mg tablets are light orange, flat tablets with two cross-sectional features on one side and engraved with the manufacturer's logo on the other side.
Clonarex 2 mg tablets are white, flat tablets with two cross-sectional markings on one side and engraved with the manufacturer's logo on the other side.

The tablets may be divided into two / four equal doses. This allows to receive lower doses at the beginning of the treatment.
Clonarex 0.5 mg and 2 mg tablets are packed in Al-PVC / PVDC blisters.
Each blister contains 10 Clonex tablets.
The carton contains 3 blisters (30 tablets).

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