Convulex caps. 300 mg. 100 capsules

WHAT ACTION HAS CONVULEX CAPSULES?

Active current substance Convulex capsules has anticonvulsant effect in various types of seizures. Moreover Convulex shows better efficiency and quick action in the treatment of acute manic phase in patients with manic-depressive disorder. When used as a preventive drug, reduces the number and severity of manic and depressive phases.

WHAT IT IS USED CONVULEX?

Convulex apply:

  The treatment of various forms of epilepsy (seizures).

  Treatment of acute manic episodes.

WHEN NOT TO BE USED CONVULEX?

Convulex not apply:

case of hypersensitivity to any of its ingredients present in liver disease;

if a family member currently has or has had severe hepatic dysfunction, hepatic porphyria (a rare metabolic disease)

CONVULEX WHEN TO BE USED WITH CARE?

Caution is required when:

  Patients with a history of liver disease or pancreas, bone marrow disorders, patients with a tendency to increased bleeding, renal dysfunction, congenital enzyme defects, and suffering from severe bouts forms

  Children with mental retardation and brain damage,

  Children under 2 years of age (as they are particularly prone to damage of the liver). In all cases, the doctor will decide the appropriateness of using Convulex.

Epilepsy

The required dosage is determined by your doctor.

In general, treatment was initiated at 15 mg / kg body weight daily. Your doctor will recommend gradually increasing the dose (by 5 to 10 mg / kg weight at weekly intervals) while achieving seizure control (mean daily dose 30 mg / kg body weight daily). Mean daily dose in children, adolescents and adults:

Recommended doses of valproate (tentative schedule)

Age - Body weight (kg) - Mean dose (mg / day)

3-6 months ~ 5.5 - 7.5 150

6-12 months -7.5-10 150-300

1 - 3 years -10-15 300-450

3-6 years - 15-20 450-600

7-11 years - 20 - 40600-1200

12 -17 years - 40 to 60 from 1000 to 1500

Adults (including the elderly)> 60 from 1200 to 2100

In general, the daily dose should be divided into several doses. If you take only Convulex for epilepsy, your doctor may recommend that you take the whole dose at once tonight.

If you have taken a long time other antiepileptic drugs, your doctor may gradually reduce their dose.

Convulex 500 mg capsules are intended for patients who require treatment of high doses already stabilized on treatment with valproic acid, as well as those aimed at maintaining therapeutic levels until the morning after the evening reception.

Manic-depressive disorder (adults only): The recommended starting dose is 500 to 1000 mg daily in divided doses. Depending on the severity of the clinical picture, the physician can prescribe up to 1500 mg daily. For a good dose adjustment may be made blood tests.

Method of application:

Swallow the capsules whole with or after a meal, with plenty of water. Overdose: An overdose of this medication can be dangerous. If you have taken an overdose, tell your doctor or seek emergency medical help immediately.

Tip for doctors:

Acute overdosage could lead to becoming unconscious state or respiratory depression. It is symptomatic treatment. Reported success of the implementation of Naloxone as an antidote.

What side effects can cause CONVULEX?

The following list lists all the side effects associated with this medicine - even those that appear very rarely.

Blood: In cases of excessive doses, treatment with valproate may result in transient abnormalities in blood counts or bleeding disorders. If bruising or increased bleeding tendency, tell your doctor immediately.

Immune system: There may be a vasculitis (inflammation of blood vessels), which can manifest as pain, redness or itching. There have been cases of allergic reactions (rash to hypersensitivity reactions) and systemic lupus rare gastropods eretematozes (ryadkosreshtano immune disorder).

Hormones: In rare cases, menstrual disorders in women and breast enlargement in men.

Metabolism: vomiting, impaired coordination, blurred saznanietomozhe continuous signal an elevated ammonia levels. If these symptoms immediately consult your doctor.

Nervous System: There have been rare cases of impaired motor coordination, dizziness, treperene.Sanlivost rarely occur mainly during concurrent treatment with other antiepileptic drugs or the early stages of monoterapiya.Dokladvani Rare cases of lethargy, confusion (sometimes followed by impaired consciousness or accompanied by hallucinations or convulsions). Very rarely transient loss of consciousness, depression, Parkinson's or dementia. If you notice any of the above symptoms or the like, contact your doctor as soon as possible.

Said side effects were generally transient and reversible upon cessation of treatment. It can be observed an increased ability to concentrate, which is generally seen as a positive effect, but in some cases can lead to hyperactivity, aggression or worsening behavior. In rare cases, partially reversible tinnitus and hearing impairment, with no evidence of their relationship to the treatment with sodium valproat.Ryadko may have headaches and eye twitching.

Gastrointestinal: Early treatment may occur with nausea, vomiting, diarrhea, loss of appetite or constipation. There are cases of weight gain due to increased appetite during treatment.

At the beginning of treatment may be a transient increase in liver enzymes. In many cases rivers may develop severe liver function disorders, sometimes fatal (see "What other precautions required?"). There are reports of rare cases of porphyria (a rare metabolic disease).