DEMEPFAN syrup 100 ml.

Demepfan is a cough suppressant agent. Unlike codeine no analgesic effects, but like it increases the threshold of the cough reflex of the central (brain) level and thus suppresses cough.
 
indications:
Symptomatic treatment of non-productive cough in colds viral proizhod.INFORMATsIYa NECESSARY BEFORE USE
 
Contraindications:
Hypersensitivity to the active and / or any of the excipients.
Bronchial asthma.
Not be used in children under 2 years.
 
Special precautions for use:
Use with caution in patients at risk of developing respiratory nedostatachnost.Lekarstveniyat product contains sorbitol and may be used in patients suffering from diabetes.
 
Interactions:
Not be administered concomitantly with MAO inhibitors and reserpine, because of the risk of serotonergic syndrome, manifested in anxiety, hyper- or hypotension, diarrhea, fever, ventricular arrhythmias, muscle rigidity, tremors, coma.
Demepfan metabolized by cytochrome P450 isoform CYP2D6 as interact with inhibitors of this enzyme: amiodarone, fluoxetine, haloperidol, paroxetine, propafenone, quinidine, procainamide, and may increase the toxicity of individual drugs in their joint administration to fasted concomitant Demepfan and fluoxetine may occur visual hallucinations.
 
Use in pregnancy and lactation:
No evidence of teratogenic effect, but for security reasons does not apply in the first three months of pregnancy and during lactation.
 
Effects on ability to drive and use machines:
On the burden of treatment Demepfan need to avoid engaging in activities requiring alertness such as driving or operating machinery.
 
INFORMATION FOR PROPER USE
dosage:
In adults:
- 10 mg (3 ml) to 20 mg (5 ml) every 4 hours or 30 mg (8 ml) every 6-8 hours.
The maximum dose should not exceed 120 mg (35 ml) / 24 hours.
 
In children:
- From 6 to 12 years:
5 mg (1,5 ml) 10 mg (3 ml) every 4 hours or 15 mg (4 ml) every 6-8 hours.
The maximum dose should not exceed 60 mg (15 ml) / 24 hours.
- From 2 to 6 years: From 3.42 mg (1 ml) to 5 mg (1,5 ml) every 4 hours or 7 mg (2 ml) every 6-8 hours.
The maximum dose should not exceed 30 mg (8 ml) / 24 hours.
 
Mode of action of overdose:
In cases of overdose, immediately contact a doctor!
Overdose prevalent symptoms of central nervous system: stupor, increased arousal Bridge, ataxia, dystonia, nystagmus, psychotic reactions, coma.
 
treatment:
Measures to accelerate the removal of the product from the body - to induce vomiting, gastric lavage, cathartic. Symptomatic means. As a specific antidote is administered naloxone.
 
Undesirable effects:
In the usual dosage side effects are rare and poorly developed: drowsiness, fatigue, dizziness, skin manifestations.
In extremely rare cases, chronic administration of Demepfan can cause drug dependence of the morphine type.
 
storage:
Dry and protected from light, at a temperature below 25 ° S.Do Keep out of reach and sight of children Shelf life: 2 (two years) from the date of manufacture.
Period of use after opening the immediate packaging: 30 days.