Euthyrox 75 mcg. 90 tablets

What is Euthyrox and what it is used for

Levothyroxine, the active substance in Euthyrox, is a synthetic thyroid hormone used to treat thyroid disease and dysfunction. It has the same effect as naturally occurring thyroid hormones.

Euthyrox is used
- for the treatment of benign goiter in patients with normal thyroid function, for the prevention of recurrence after goiter surgery,
- to replace natural thyroid hormones with reduced production of hormones by your thyroid gland,
- to suppress tumor growth in patients with thyroid cancer.

Euthyrox 25 micrograms, 50 micrograms, 75 micrograms and 100 micrograms are also used to balance thyroid hormone levels when hormone overproduction is treated with antithyroid drugs.

Euthyrox 100 micrograms can also be used to test your thyroid function.

2. What you need to know before you take Euthyrox

Do not take Euthyrox
if you have:
- allergy (hypersensitivity) to the active substance or to any of the other ingredients of Euthyrox (listed in section 6),
- untreated dysfunction of the adrenal gland, pituitary gland or excessive overproduction of thyroid hormones (thyrotoxicosis),
- acute heart disease (myocardial infarction or inflammation of the heart).

If you are pregnant, do not take Euthyrox with antithyroid medicines (see section "Pregnancy and breast-feeding" below).

Warnings and precautions
Talk to your doctor or pharmacist before taking Euthyrox if you have any of the following heart conditions:
- insufficient blood flow in the blood vessels of the heart (angina pectoris),
- heart failure,
- fast and irregular heartbeat,
- high blood pressure,
- fatty deposits in the arteries (atherosclerosis).

They should be controlled with medication before you start taking Euthyrox or before a suppressive thyroid test. While you are on Euthyrox, your thyroid hormone levels should be checked frequently. If you are not sure if you have any of these conditions or if you are not receiving treatment, contact your doctor.

Your doctor will test you if you have adrenal or pituitary dysfunction, or thyroid dysfunction with uncontrolled overproduction of thyroid hormones (thyroid autonomy), as these must be medically controlled before you start taking eu or examination of the thyroid gland.

Talk to your doctor,
- if you are menopausal or post-menopausal; Your doctor may need to check your thyroid function regularly because of the risk of osteoporosis.
- if you switch from one levothyroxine-containing medicine to another. The effect may be slightly different and you may need more frequent testing and dose adjustment.
- before taking orlistat (used to treat obesity; you may need to be monitored more often and your dose adjusted)
- if you have symptoms of mental disorders (you may need to be monitored more often and your dose may need to be adjusted).

Other medicines and Euthyrox
Tell your doctor or pharmacist if you are taking, have recently taken or might take any of the following medicines, as Euthyrox may affect their effect:

- Antidiabetic medicines (medicines that lower blood sugar):
Euthyrox may reduce the effect of your antidiabetic medicine, so you may need further tests on your blood sugar levels, especially at the beginning of treatment with Euthyrox. The dose of your antidiabetic medicine may need to be adjusted while you are taking Euthyrox.

- Coumarin derivatives (medicines used to prevent blood clotting): Euthyrox may increase the effect of these medicines, which may increase the risk of bleeding, especially in the elderly. Regular monitoring of coagulation parameters may be required at the beginning and during treatment with Euthyrox. The dose of coumarin may need to be adjusted while you are taking Euthyrox.

Make sure you follow the recommended dosing intervals if you need to take the following medicines:
- Medicines that bind to bile acids and lower high cholesterol (such as cholestyramine or cholestipol):
Make sure you take Euthyrox 4-5 hours before these medicines, as they may block the absorption of Euthyrox from the gut.
- Antacids (to relieve stomach acid), sucralfate (for stomach or intestinal ulcers), other aluminum-containing medicines, iron-containing medicines, calcium-containing medicines:
Make sure you take Euthyrox at least 2 hours before these medicines, as otherwise they may reduce the effect of Euthyrox.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any of the following medicines, as they may reduce the effect of E.
Duration of treatment
The duration of treatment may vary, depending on the condition for which you are using Euthyrox. Therefore, your doctor will discuss with you how long you should take it. Most patients take Euthyrox for life.

If you take more Euthyrox than you should
If you take more than the prescribed dose, you may experience symptoms such as a fast heartbeat, anxiety, excitement or involuntary movements. Isolated cases of seizures may occur in patients with nervous system disorders, eg epilepsy. Symptoms of acute psychosis may occur in patients at risk of mental disorders. If this happens, call your doctor.

If you forget to take Euthyrox
Do not take a double dose to make up for a forgotten tablet, but take the normal dose the next day.

If you have any further questions on the use of Euthyrox, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, Euthyrox can cause side effects, although not everybody gets them.

If you take Euthyrox in a dose higher than the prescribed dose, or if you do not tolerate the prescribed dose (eg when the dose is increased rapidly), you may get one or more of the following side effects:

Irregular or fast heartbeat, chest pain, headache, muscle weakness or cramps, flushing (warming and flushing of the face), fever, vomiting »menstrual disorders, pseudotumor cerebri (increased head pressure), tremors, restlessness, disorders of the sleep, sweating, weight loss, diarrhea.

If you get any of these side effects, talk to your doctor. Your doctor may decide to stop treatment for a few days or reduce the daily dose until the side effects disappear.

Allergic reactions to any of the ingredients of Euthyrox are possible (see section 6. "What Euthyrox contains"). Allergic reactions can occur with swelling of the face or throat (angioedema). If this happens, contact your doctor immediately.
5. How to store Euthyrox

Keep out of reach of children.

Do not use Euthyrox after the expiry date which is stated on the blister and the carton after EXP. The expiry date refers to the last day of that month.

Store below 25 ° C. Keep the blisters in the outer carton in order to protect from light.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Package contents and additional information

What Euthyrox contains
- The active substance is levothyroxine. Each tablet contains 25 micrograms, 50 micrograms, 75 micrograms, 100 micrograms, 125 micrograms levothyroxine sodium. The other ingredients are cornstarch, citric acid, croscarmellose sodium, gelatin, magnesium stearate and mannitol (E421).

What Euthyrox looks like and contents of the pack
Euthyrox tablets are almost white, round, bilaterally flat, scored, with bevelled edges and labeled on one side: EM 25, EM 50, EM 75, EM 100 or EM 125. Euthyrox is available in packs of 30, 50, 90 or 100 tablets.

Not all pack sizes may be marketed.

 

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