Irbesartantable.300 mg.  28 tablets

Whatirbesartan accord and what it is used

IrbesartanAccordbelongs to a groupof medicines calledreceptor antagonistsforangiotensin-II.
Angiotensin-II is asubstanceproducedin the bodywhich bindsto receptors inblood vesselscausing themto constrict.Therebyincreasingblood pressure.AccordIrbesartanprevents the bindingof angiotensin-IIto these receptors,thusblood vesselsrelax and bloodpressure is lowered.IrbesartanAccordpreventsdeteriorationof renalfunction in patients withhypertension andtype 2 diabetes.

Before you take Irbesartan accord

Do not takeIrbesartanAccord:

- Ifyou are allergic(hypersensitive) to irbesartan orany other ingredientsofIrbesartanAccord;
- If you are inthe second orthirdtrimester ofpregnancy;
- If you are breastfeeding.
  IrbesartanAccordshould not betaken by childrenand teenagersunder 16years of age.

Take special carewith IrbesartanAccord:
Tell yourdoctorbefore takingIrbesartanAccordif:

-suffer fromsevere vomitingor diarrhea;
- You suffer fromkidney disease;
- You suffer fromheart disease;
- GetIrbesartanAccordof diabeticnephropathy.In thiscase, yourdoctor may orderlaboratory tests, especially for measuring the levelsof sodiumin the bloodin cases ofimpairedrenalfunction.
- You suffer fromprimary aldosteronism, a condition in whichyour adrenalglands producetoo much hormonealdosteronereason toretainsodium andpotassiumwasting.
- You suffer fromarterial stenosis(narrowingor blockage ofthe arterythat suppliesblood to thekidneys).

Taking othermedicines:

Please tell yourdoctor orpharmacistif you are takingor have recentlytaken any othermedicines, includingmedicines obtainedwithout a prescription.
IrbesartanAccordusually do notinteract with othermedications.
You have todolaboratory testsif you are taking:

- potassium supplements;
- salt substitutesthat containpotassium;
- Potassium-sparing medicines (such as certaindiuretics);
- Drugs thatcontainlithium.

IrbesartanAccordwith food and drink
IrbesartanAccordtabletscanbe taken with orwithout food.Tablets should beswallowed withwater.

Pregnancyand lactation:
Ask yourdoctor or pharmacistbefore takingany medicine.Tell yourdoctor ifyou are pregnantorplan to become pregnant.Your doctor will normallyadvise youto take anothermedicine instead ofIrbesartanAccordasAccordIrbesartanis not recommendedin early pregnancy andmay causeserious harm to yourbaby ifused after the thirdmonth of pregnancy.Appropriateantihypertensive drugusuallymust replaceIrbesartanAccordbeforepregnancy.The productshould not beused duringthe 2ndand Hrdtrimester of pregnancyor duringlactation.
Your doctor will normallyadvise youto stop takingIrbesartanAccordas you knowyou are pregnant.If you become pregnantduring treatment withIrbesartanAccord, pleasetell yourdoctor andsee himimmediately.

Breastfeeding
You should not take Irbesartan Accord if you are breastfeeding (see "Before you take Irbesartan Accord").

Driving and operating machinery
No studies on the effects on ability to drive and use machines. Irbesartan Accord is unlikely to affect your ability to drive or operate machinery. Sometimes it may appear dizziness or fatigue during the treatment of high blood pressure. If you feel, you should consult your doctor before performing these activities.

Important information about some of the ingredients of Irbesartan Accord
This medicinal product contains lactose. If your doctor tells you that you have an intolerance to some sugars, contact your doctor before taking this medicine. Patients with rare hereditary enzyme defects of galactose intolerance, hereditary lactase deficiency or poor absorption of glucose and galactose should not use this product.

How to take Irbesartan

Always take Irbesartan Accord exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.
The usual dose is 150 mg once daily. In the course of treatment the dose may be increased to 300 mg once daily, depending on the blood pressure. Optimal blood pressure will be reached by 4 to 6 weeks after initiation of therapy.
In patients with hypertension and type 2 diabetes, 300 mg once daily is the recommended maintenance dose for treatment of related kidney disease.
Your doctor may recommend a lower dose, especially when starting treatment in certain patients, such as patients on hemodialysis or patients older than 75 years.
Irbesartan Accord tablets are for oral use. The tablets should be swallowed with a sufficient amount of fluid (eg one glass of water). You can take Irbesartan Accord with or without food. You should try to take your daily dose at one time each day. It is important to continue to take Irbesartan Accord until your doctor tells you to stop or change treatment.

If you take more Irbesartan dose Accord
If you accidentally take more tablets than your doctor has appointed nezabavnose contact your doctor or go to the nearest hospital. Symptoms of overdose include a sharp drop in blood pressure (hypotension) and fast heartbeat (tachycardia).

If you forget to take Irbesartan Accord
If you accidentally miss a daily dose, just take the next dose as usual. Do not take a double dose to make up for a missed dose.

If you stop taking Irbesartan Accord:
Do not discontinue treatment without consulting your doctor. It is important to take Irbesartan Accord as long as your doctor has prescribed. This will keep your blood pressure within normal limits and / or to protect your kidneys from damage.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

Possible side effects

Like all medicines, Irbesartan Accord can cause side effects, although not everybody gets them.
In each group, depending on the frequency of adverse reactions are presented in order of decreasing seriousness.

Adverse reactions are ranked by frequency as follows:
Very common: More than 1 in 10 patients;
Common: 1 to 10 of 100 people;
Uncommon: 1 to 10 of 1000 patients treated;
Rare: 1 to 10 of 10,000 patients treated;
Very rare: less than 1 in 10,000 patients treated.