Letrocon 2.5 mg. 28 tablets

What Letrocon is and what it is used for
What Letrocon is and how it works
Letrocon contains an active substance called letrozole. It belongs to a group of medicines called aromatase inhibitors. It is used for hormonal (or endocrine) treatment of breast cancer. Tumor growth in breast cancer is often stimulated by estrogen. which are the female sex hormones. Letrocon reduces the amount of estrogen by blocking an enzyme (aromatase) involved in their formation, and thus can block the growth of breast cancer, which needs estrogen for its growth. As a result, tumor cells slow down or stop growing and / or spreading to other parts of the body.

What Letrocon is used for
Letrocon is used to treat breast cancer in postmenopausal women. i.e. cessation of menstruation.

It is used to prevent the recurrence of cancer. It can be used as a first treatment before breast cancer surgery, in case immediate surgical treatment is inappropriate. It can be used as the first treatment after breast cancer surgery and after five years of tamoxifen treatment. Letrocon is also used to prevent the spread of the tumor to other parts of the body in advanced breast cancer.

If you have any questions about how Letrocon works or why you have been prescribed this medicine, ask your doctor.

2. What you need to know before you take Letrocon
Follow your doctor's instructions carefully. They may differ from the general information in this leaflet.

Do not take Letrocon:
if you are allergic to letrozole or any of the other ingredients of Letrocon (listed in section 6);
if you are still menstruating, ie if you are not yet menopausal:
if you are pregnant;
if you are breast-feeding.
If any of these apply to you, do not take this medicine and talk to your doctor.

Warnings and precautions
Talk to your doctor or pharmacist before taking Letrocon:

if you have severe kidney disease;
if you have severe liver disease;
if you have a history of osteoporosis or bone fractures (see also Lrosldsdiaans during treatment with Letrocon "in section 3).
If any of these apply to you, tell your doctor. Your doctor will take this into account during your treatment with Letrocon.

Children and adolescents (under 18)

Children and adolescents should not take this medicine.

Elderly patients (65 years of age or older)

Patients aged 65 years and older can use this medicine in the same doses as other adults.

Other medicines and Letrocon
You should tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.

Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

You should only take Letrocon if you have reached menopause.

Nevertheless. Your doctor should discuss with you the need for effective contraception, as it is still possible to become pregnant during treatment with Letrocon.

You should not take Letrocon if you are pregnant or breast-feeding, as this may harm your baby.

Driving and using machines
If you feel dizzy, tired, sleepy, or generally unwell, do not drive or use any tools or machines until you feel normal again.

Letrocon contains lactose
Letrocon tablets contain lactose (milk sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

3. How to take Letrocon
Always take Letrocon exactly as your doctor or pharmacist has told you. If you are not sure, talk to your doctor or pharmacist.

The recommended dose is one Letrocon tablet once a day. Take Letrocon at the same time each day to remember when to take it.

The tablet can be taken with or without food and should be swallowed whole with a glass of water or other liquid.

How long to take Letrocon

Continue to take Letrocon every day for as long as your doctor tells you. It may take months or even Jews. If you have any questions about the duration of Letrocon, talk to your doctor.

Follow-up during treatment with Letrocon

You should only take this medicine under strict medical supervision. Your doctor will monitor your condition regularly to check that the treatment is having the desired effect.

Letrocon can cause thinning or weakening of the bones (osteogurosis) as a result of a decrease in estrogen in the body. Your doctor may decide to measure your bone density
If you take more Letrocon than you should
If you take too much Letrocon or if someone else accidentally takes your tablets, contact your doctor or hospital immediately. Show them a pack of tablets - Medical treatment may be needed.

If you forget to take Letrocon
If it is almost time for your next dose (2-3 hours), do not take the missed dose and take your next dose at the usual time.

Otherwise, take the missed dose as soon as you remember and then take the next tablet at the usual time.

Do not take a double dose to make up for a forgotten dose.

If you stop taking Letrocon
Do not stop taking Letrocon unless your doctor tells you to. See also "How long to take Letrocon".

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, Letrocon can cause side effects, although not everybody gets them.

Most side effects are mild to moderate and generally resolve within a few days to a few weeks of treatment.

Some of the side effects, such as hot flashes, hair loss or vaginal bleeding, may be due to a lack of estrogen in your body.

Some side effects can be serious.

Rare or uncommon side effects (ie may affect between 1 and 100 in every 10,000 patients):
weakness, paralysis or loss of sensation in any part of the body (especially arm or leg), loss of coordination, nausea or difficulty speaking or breathing (a sign of brain damage, stroke);
sudden tightening pain in the chest (a sign of heart disease);
difficulty breathing, chest pain, fainting, rapid heartbeat, bruising of the skin or sudden pain in the arm, leg or foot (signs of possible clots);
swelling or redness along the vein, which is particularly sensitive and painful to the touch;
severe fever, chills or cold sores in the mouth due to infection (lack of white blood cells);
severe permanent blurred vision.
If any of the above symptoms occur, tell your doctor immediately.

You should also tell your doctor immediately if you experience any of the following symptoms during treatment with Letrocon;
swelling of the face and throat (a sign of an allergic reaction);
yellowing of the skin and eyes, nausea, loss of appetite, dark urine (signs of hepatitis);
rash, reddening of the skin, swelling of the lips, eyes or mouth, peeling of the skin, fever (signs of skin disease).
Some side effects are very common. They can affect more than 10 in 100 patients
hot flashes;
high cholesterol;
fatigue;
profuse sweating;
bone and joint pain (arthralgia).
If any of these side effects affect you severely, tell your doctor.

Some side effects are common (they may affect between 1 and 10 in every 100 patients):
skin rashes;
headache;
dizziness;
general malaise;
gastrointestinal disorders such as nausea, vomiting, indigestion, constipation, diarrhea;
increase or loss of appetite;
muscle pain;
thinning or wear of the bones (osteoporosis), which leads to bone fractures in some cases (see also section "Follow-up during treatment with Letrocon" in section 3);
swelling of the hands, palms, feet, ankles (swelling);
sad mood (depression);
weight gain;
hair loss;
high blood pressure (hypertension);
stomach ache;
dry skin;
vaginal bleeding.
If any of these side effects affect you severely, tell your doctor.

Other side effects are uncommon (they may affect between 1 and 10 users in 1,000):
nervous disorders such as anxiety, nervousness, irritability, drowsiness, memory problems, drowsiness, insomnia:
sensory disturbances, especially with touch;
eye disorders such as blurred vision, eye irritation;
palpitations, rapid heartbeat (rapid pulse);
skin disorders such as itching (urticaria);
vaginal discharge or dryness;
joint stiffness (arthritis);
chest pain;
fever;
thirst, taste disturbances, dry mouth;
drying of the mucous membranes;
weight loss;
urinary tract infection, frequent urination;
cough;
elevated levels of enzymes.
If any of these side effects affect you severely, tell your doctor.
5. How to store Letrocon
Keep out of reach of children.

Do not use Letrocon after the expiry date which is stated on the pack. The expiry date refers to the last day of that month. This medicine does not require any special storage conditions.

Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the package and additional information
What Letrocon contains
- Active substance: letrozole. Each film-coated tablet contains 2.5 mg letrozole.

Other ingredients:

core: lactose monohydrate. croscarmellose sodium, povidone, colloidal anhydrous silica, magnesium stearate:

shell; peel yellow 03B82401 - yellow iron oxide (E 172). quinromelose ber (E 464), macroul 400. titanium dioxide (E 171). talc (E553b),

What Letrocon looks like and contents of the pack
Letrocon are dark yellow, round, slightly biconvex film-coated tablets with bevelled edges engraved with "5" on one side and "H" on the other.

The pack contains 28 or 30 tablets.

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