What is Lorinden A ointment and what it is used for
The components of Lorinden A Ointment show a combined effect in the treatment of keratinized inflammatory skin changes with allergic origin.
Flumazazole pivalate is a synthetic glucocorticosteroid intended for topical application to the skin. It has a moderately powerful anti-inflammatory, anti-inflammatory, anti-allergic and vasoconstrictive effect.
Salicylic acid acts locally on the skin surface, facilitating the penetration of the glucocorticoid via the epidermis with hyperkeratosis.
Lorinden A in the form of an ointment is used topically for the treatment of dry skin inflammatory conditions, in particular those of allergic origin, uncomplicated by secondary bacterial infection, hyperkeratosis and persistent itching. The medicinal product is specifically used to treat:
seborrheic dermatitis;
atopic dermatitis;
allergic contact eczema;
erythema multiforme;
lupus erythematosus;
persistent psoriasis;
lichen planus.
2. What you need to know before using Lorinden A Ointment
Do not use Lorinden A Ointment:
if you are allergic to flumetasone pivalate, other glucocorticosteroids, salicylic acid and any of the other ingredients of this medicine (listed in section 6);
viral, fungal or tuberculous skin diseases, skin tumors, usually acne or acne rosacea, varicella, varicose inflammation or ulceration (trophic ulcer of lower limbs), syphilis, perioral dermatitis;
on large skin areas, particularly damaged, e.g. burns;
during the first trimester of pregnancy.
in children under the age of 2 years.
Warnings and precautions
Talk to your doctor or pharmacist before using Lorinden A Ointment:
Do not apply without interruption for periods longer than 2 weeks. In the long-term treatment of large areas of skin, the incidence of side effects is increased.
Due to the local administration of flumetasone pivalate, adrenocorticotropic hormone (ACTH) secretion from the pituitary can be reduced due to suppression of the adrenocortical pituitary axis, resulting in a decrease in blood cortisol concentration and Cushing's iatrogenic syndrome. With discontinuation of treatment, this passes. Periodic adrenal gland function testing is recommended to determine the cortisol concentration in the blood and urine after stimulation of the adrenal gland with ACTH.
If an infection is exacerbated after an ointment, additional antibacterial or antifungal treatment should be performed. If the symptoms of the infection do not disappear, the ointment should be discontinued until it is cured.
Avoid using the drug on the eyelids or the skin around them, due to the risk of glaucoma or cataracts. In patients with glaucoma or cataracts, the symptoms of the disease may be exacerbated.
The medicinal product can be applied to the facial, armpit and groin skin only when absolutely necessary because of increased absorption and increased likelihood of developing side effects (telangiectasia, perioral dermatitis) even after short treatment.
The use of the occlusive dressing product should be limited to exceptional cases because it may lead to epidermal atrophy, stretch marks and severe infections. Apply with caution to existing atrophic conditions of the subcutaneous tissue, especially in older patients.
To be used with caution in patients with psoriasis. Local administration of corticosteroids in psoriasis may be risky due to the possibility of relapse due to developed tolerance, risk of generalized pustular psoriasis and systemic toxicity due to dysfunction of the skin.
Special attention should be paid to children over 2 years of age.
In children, due to the higher body-to-body ratio than adults, there is an increased risk of systemic adverse reactions of glucocorticosteroids, including dysplasia of the hypothalamic-pituitary-adrenal gland and Cushing's syndrome. Treatment with corticosteroids may adversely affect the growth and development of children.
Contact your doctor if you have blurred vision or other visual disturbances.
Other medicines and Lorinden A Ointment
Tell your doctor or pharmacist if you are using, have recently used or are likely to use other medicines, including medicines obtained without a prescription.
There are no proven drug interactions associated with topical administration of glucocorticosteroids.
However, during treatment with glucocorticoids, patients should not be vaccinated against smallpox. Other types of immunization are not recommended, especially in long-term treatment of large skin surfaces due to the risk of lacking an antibody-mediated immune response. The drug may activate the immunosuppressive agents and suppress that of the immunostimulants.
Pregnancy and breastfeeding
If you are pregnant or are breast-feeding, think you may be pregnant or plan to become pregnant, ask your doctor or pharmacist for advice before taking this medicine. The use of Lorinden A in pregnant and lactating women is not recommended. It can be used during pregnancy and lactation for a short period of time and on a small area of the skin only if absolutely necessary and if the benefit to the mother outweighs the risk to the fetus.
It is absolutely contraindicated to use during the first trimester of pregnancy.
Lorinden A ointment contains propylene glycol and lanolin, which can cause local skin reactions (eg contact dermatitis) or irritation.
3. How to use Lorinden A Ointment
Always use this medicine exactly as your doctor or pharmacist has told you. If you are not sure, ask your doctor or pharmacist.
Apply a thin layer of ointment to the affected skin, no more than once or twice a day.
In the case of excessive lichenification or hyperkeratosis of skin lesions, it is acceptable to use an occlusive dressing, which should be changed every 24 hours.
Duration of treatment
Treatment should not last for more than two weeks.
Do not apply in the person's area for longer than one week.
Do not use more than one ointment a week.
Do not apply to the skin of the face.
Use in children
To be used with caution in children over 2 years of age, only once daily, on small areas of skin.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.
Skin and subcutaneous tissue disorders
Acne, small spotted blemishes (purpura), thinning of the skin and subcutaneous tissue, dry skin, excessive hair growth or hair loss, skin coloring and discoloration, skin atrophy and stretch marks, enlargement of the small blood vessels of the skin or mucous membranes, inflammation of the skin around the mouth, folliculitis, skin irritation and secondary infection.
Sometimes urticaria or maculopapular rashes, aggravation of existing lesions.
Prolonged treatment is possible for dermatitis due to the salicylic acid content.
Eye disorders
Topical application to the eyelids may lead to glaucoma or cataracts.
Blurred vision.
Endocrine system disorders
Because of the absorption of flumetasone pivalate and salicylic acid through the skin, systemic side effects may occur, especially in prolonged use, application to large areas of the skin, occlusive dressing, and children. The systemic side effects of flumetazone pivalate, which are characteristic of corticosteroids, are suppression of the hypothalamic-adrenal-pituitary axis, Cushing's syndrome, depression of growth and development in children, hyperglycemia, glucosuria, edema, hypertension, decreased immunity.
How to Store Lorinden A Ointment
Keep out of the reach and sight of children.
Store below 25 ° C.
Do not use Lorinden A ointment after the expiry date which is stated on the pack. The expiry date refers to the last day of that month.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Package Contents and Additional Information
What Lorinden contains A ointment:
The active substances are: flumetasone (as pivalate) 0.2 mg and salicylic acid 30 mg in 1 g ointment.
The other ingredients are: propylene glycol, lanolin, paraffin, white soft.
What Lorinden A looks like and what the package contains
Lorinden A ointment is a white ointment with a pale yellowish tint.
The aluminum tube contains 15 g of ointment. Each tube together with a leaflet is packed in a cardboard box.