Zeldox 40 mg. 14 capsules

What Zeldox capsules and what it is used
Zeldox capsules belongs to a group of medicines called antipsychotics (neuroleptics).
Zeldox capsules are used to treat the symptoms of schizophrenia in adults. Schizophrenia is a mental disorder that has the following symptoms: hear, see or feel things that are not there, believe things that are not true, unusually suspicious you are distracted and difficult to communicate, you feel nervous, depressed or anxious.
Zeldox capsules are also used to treat the symptoms of manic or mixed episodes associated with bipolar disorder in adults, children and adolescents aged 10-17 years. Bipolar disorder is a mental disorder that is characterized by moods, changing from euphoria (mania) to depression. During manic episodes, the most characteristic symptoms include elevated mood, increased self-esteem, increased energy, decreased need for sleep, lack of concentration or hyperactivity and risky behavior.

2. What you need to know before taking Zeldox capsules
Do not take Zeldox capsules:
if you are allergic to ziprasidone or any of the other ingredients of this medicine (listed in section 6). Allergic reactions can manifest as rash, itching, swollen face, swollen lips or shortness of breath. If that ever happened, tell your doctor;
if you have ever had heart problems. You should tell your doctor if you have had any heart problems;
if you are taking medicines for heart rhythm problems, or those that affect heart rhythm.
Warnings and Precautions
if you or someone in your family has had problems with blood clots, since such drugs are associated with blood clots;
if you have liver problems;
If you receive or have received seizures or suffer from epilepsy;
if you are over 65 and have dementia, and have an increased risk of stroke;
if you have a low heart rate and / or know that your body salts lost due to prolonged or severe diarrhea or after the use of water tablets (diuretics);
if you have experienced palpitations or irregular heartbeats, fainting or dizziness after standing up which may indicate abnormal heart rhythm.
Please tell your doctor that you are taking Zeldox capsules before undergoing laboratory tests (such as blood tests, urine, liver function, heart beat), because this medicine can affect your performance.

Other medicines and Zeldox
Tell your doctor if you are taking, have recently taken or might take any other medicines.
Do not take Zeldox if you are taking medicines for heart rhythm problems or that affect heart rate, such as:
Antiarrhythmics of class IA and III, the arsenic trioxide, halofantrine, levomethadyl acetate, mesoridazine, thioridazine, pimozide, sparfloxacin, gatifloxacin, moxifloxacin, dolasetron mesilate, mefloquine, sertindole or cisapride. These drugs affect heart rate, leading to changes in the electrocardiogram you (prolong the QT interval). If you have any further questions on the use of this product, ask your doctor.
Please tell your doctor if you are taking or have recently taken medicines to treat:
bacterial infections; These drugs are known as antibiotics; as macrolide antibiotics or rifampicin;
mood swings (ranging from depression to euphoria), agitation or irritability; These drugs are known as mood stabilizers, e. lithium, carbamazepine, valproate;
depression, including certain serotonergic drugs, e. selective inhibitors of serotonin reuptake, such as fluoxetine, paroxetine, sertraline; or herbal products containing St. John's wort;
epilepsy, e. phenytoin, phenobarbital, carbamazepine, ethosuximide;
a condition that occurs with tremor, stiffness and shuffling (Parkinsonism), eg. levodopa, bromocriptine, ropinirole, pramipexole;
if you are taking or have recently taken the following medicines: verapamil, quinidine; itraconazole, or ritonavir.
Zeldox capsules with food and drink
Zeldox capsules should be taken with food.
You should not drink alcohol while taking Zeldox capsules, as this could increase the risk of side effects.

Pregnancy and lactation
pregnancy
Zeldox capsules should not be used during pregnancy unless your doctor has told you otherwise, since there is risk of the fetus. Women of childbearing potential must use effective contraception. Immediately contact your doctor if you are pregnant or planning to become pregnant while taking Zeldox capsules. Ask your doctor or pharmacist before taking any medicine.
The following symptoms may occur in newborn babies of mothers taking Zeldox in the last trimester (last three months of pregnancy): shaking, muscle stiffness and / or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding. If your baby develops any of these symptoms, contact your doctor.

breastfeeding
It is not recommended to breast-feed your baby while taking Zeldox capsules, as it is not known whether Zeldox capsules are excreted in human milk. Ask your doctor or pharmacist before taking any medicine.

Driving and using machines
Zeldox capsules can cause drowsiness. Do not drive, operate machinery or perform other potentially dangerous activities until drowsiness does not pass.

Important information about some of the ingredients of Zeldox capsules
If your doctor has told you that you have an intolerance to some sugars (such as lactose), contact your doctor before taking this medicine.

3. How to take Zeldox capsules
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Swallow the capsules whole with food. It is important not to chew, as this may influence the degree to which Zeldox absorbed in the intestine.
Take Zeldox capsules twice a day, one capsule in the morning during breakfast and one evening during the evening meal (see. Blister). It is necessary to take Zeldox capsules at the same time each day:
The image of the sun on the blister notes morning dose;
The image of the moon on the blister notes evening dose.
adults
The usual dose is between 40 mg and 80 mg twice a day taken with food. Your doctor may reduce your dose if you have to take Zeldox capsules for a long time. Should not exceed a dose of 160 mg daily.

children
The usual starting dose is 20 mg, taken with food. Your doctor will determine the best dose for you. Should not exceed a maximum dose of 80 mg per day in children weighing 45 kg or less and 160 mg per day in children weighing more than 45 kg.

Elderly (over 65 years)
If you are aged over 65, your doctor will decide the most appropriate dose for you. It is possible that the dosages in humans over 65 years are lower than those in younger people. Your doctor will determine which is the correct dose for you.

Patients with liver problems
If you have liver problems may need to take lower doses Zeldox capsules. Your doctor will determine which is the correct dose for you

If you take more than the amount Zeldox capsules
Immediately contact your doctor or the nearest emergency department. Bring your box of Zeldox capsules with you.
If you take too many capsules Zeldox can feel drowsiness, tremor, get fit of hysteria or involuntary movements of the head and neck.

If you forget to take Zeldox capsules
It is important to take Zeldox capsules regularly at the same time each day. If you forget to take a dose, take it as soon as you remember unless it is time for your next dose. In this case, just take your next dose. Do not take a double dose to make up the missed dose.

Effects when treatment with Zeldox capsules:
Your doctor will tell you how long to take Zeldox capsules. Do not stop taking Zeldox capsules unless your doctor has told you to do it.
It is important to continue taking your capsules, even if you feel better. If you stop treatment too early, your symptoms may recur.

If you have any further questions on the use of this product, ask your doctor.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Most side effects are transient. You may find it difficult to distinguish the symptoms of your illness side effects.

Stop taking Zeldox capsules and immediately contact your doctor if you experience any of these serious side effects:
Uncommon side effects which may affect more than 1 person in 1000:
Palpitations or irregular heart beat, feeling dizzy when standing, which may indicate abnormal functioning of the heart. These symptoms may occur with a condition called postural hypotension;
Involuntary movements, especially of the face or tongue.
Side effects with unknown frequency (frequency can not be estimated from available data):
Swelling of the face, lips, tongue and throat, difficulty swallowing or breathing, rash. These may be symptoms of a severe allergic reaction called angioedema;
Fever, rapid breathing, sweating, muscle stiffness, shaking, difficulty swallowing and impaired consciousness. These may be symptoms of a condition called neuroleptic malignant syndrome;
Clouding of consciousness, agitation, fever, sweating, loss of coordination of movements, muscle twitching. These may be symptoms of a condition called serotonin syndrome;
Rapid and irregular heartbeat, loss of consciousness, which can be symptoms of a life-threatening condition called Torsade de Pointes.
It may also be any of those described below side effects. These possible side effects are mild to moderate and may resolve with time. However, if any of these reactions are severe or prolonged, please contact your doctor.

Common side effects which may affect more than 1 person in 100:
anxiety;
Movement disorders, including muscle stiffness and tension, slow movements, tremor, feeling weak or nemoshtnost;
drowsiness;
headache;
dizziness;
Constipation, nausea, vomiting, indigestion, dry mouth, increased salivation;
Blurred vision.
Uncommon side effects which may affect more than 1 person in 1000:
Increased appetite;
Difficult control of movements;
Agitation, anxiety, throat tightness, restless dreams;
Seizures, unusual eye movements, clumsiness, speech disturbances, numbness, tingling, drooling, drowsiness, exhaustion;
Palpitations or irregular heart beat, feeling dizzy when you stand up, shortness of breath;
Photophobia, tinnitus;
Difficulty swallowing, swollen tongue, diarrhea, flatulence, stomach discomfort;
Rash, hives (hives), acne;
Muscle cramps, stiff or swollen joints;
Thirst, pain, chest discomfort, irregular gait.
Rare side effects that may affect less than 1 person in 1000:
Running nose;
Decreased levels of calcium in the blood;
Panic attack, feeling depressed, slowed thinking, lack of emotion;
Unusual position of the head (neck Wry, torticollis), paralysis, "restless legs";
Partial or complete loss of vision in one eye, itchy eyes, dry eyes, visual disturbances;
Ear pain;
hiccups;
acids;
Loose stools;
Hair loss, facial swelling, skin irritation;
Inability to open the mouth;
Incontinence, painful or difficult urination;
Decreased or increased erection, diminished ability to reach orgasm, abnormal separation of the fluid from the mammary glands;
Breast enlargement in men and women;
Hot flushes, fever;
Reduction or increase in white blood cells (in blood tests);
Abnormalities in liver function;
High blood pressure;
Abnormal blood tests or abnormal heart beat;
Lots red and inflamed skin covered with white scales (psoriasis).
Side effects with unknown frequency (frequency can not be estimated from available data):
Serious allergic reaction;
In elderly patients with dementia treated with antipsychotics, the risk of death was slightly higher compared to patients who were not treated;
Blood clots in the veins especially in the legs (symptoms include swelling, pain and redness in the leg), which may in the way of blood vessels to reach the lungs and cause chest pain and shortness of breath. If you experience any of these symptoms, please seek medical advice immediately;
Disturbed sleep, loss of urine;
Extremely high spirits, strange thoughts and hyperactivity;
Loss of consciousness;
Large hives (hives) with severe itching;
Prolonged and painful erection;
Sagging of the face;
Withdrawal symptoms in newborns.
If any of these side effects become troublesome, severe, or does not recover in the course of treatment, tell your doctor.
If you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. How to store Zeldox capsules
Keep out of reach of children.
Do not store above 30 ° C.