PRADAXA table. 110 mg. 10 table

PRADAXA WHAT IS AND WHAT IT IS USED FOR?

Pradaxa is a medicine used to prevent blood clots. It works by blocking a substance in the body that is involved in the formation of blood clots.

Pradaxa used to prevent blood clots in the veins after knee or hip replacement.

BEFORE YOU TAKE PRADAXA

Do not take Pradaxa:

 If you are allergic to dabigatran etexilate, dabigatran or any of the other ingredients of Pradaksa

  If you have severely reduced kidney function

  If you are currently bleeding

 If you have a body in the body that increases the risk of serious bleeding

  If you have an increased tendency to bleed, which can be congenital, of unknown origin or caused by other drugs

  If you have severely reduced liver function or liver disease that may cause death

  If you are taking quinidine - medicine for irregular heartbea 

Take special care with Pradaxa

Inform your doctor if you have or have had any medical conditions or illnesses, especially any of those included in the following list:

  If you have liver disease, which is associated with changes in blood tests Pradaksa use is not recommended.

  If you have an increased risk of bleeding, which may be the case in the following situations:

 If you surgically sampled by tissue removal / biopsy / in recent months

  If you had a serious injury

  If you are undergoing treatment, which may increase the risk of bleeding

  If you are taking anti-inflammatory drugs

  If you have a heart infection / bacterial endocarditis /

  If you have moderately impaired renal function

Pradaxa should not be used in children 

 If you have a trabichna / catheters / back

In your back can be a tube, such as anesthesia or pain relief during or after surgery. If you have been prescribed Pradaxa after removing katerara, your doctor should examine you regularly.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those awarded without a prescription.

For example:

  Medicines to thin the blood

 NSAIDs

  St. John's Wort, rifampicin, verapamil, clarithromycin

  Amiodarone, verapamil

If you are taking medicines containing amiodarone or verapamil should be treated with less than 150 mg doaz Pradaxa because your risk of bleeding may be increased.

If you are taking medicines containing verapamil, and the function of your kidneys is reduced by more than half, you should be treated with a reduced dose of 75 mg Pradaxa because your risk of bleeding may be increased.

Taking Pradaxa with food and drink

Pradaxa can be taken with or without food.

Pregnancy and lactation

Pradaksa effects on pregnancy and the unborn child are not known. You should not take Pradaksa if you are pregnant unless your doctor tells you it is safe to do so. If you are a woman of childbearing potential should avoid becoming pregnant while taking Pradaksa. You should not breast-feed while taking Pradaksa.

HOW TO TAKE PRADAXA

When removing Pradaksa capsule blister pack, please observe the following guidelines

  Take the capsules by peeling off the backing foil blister card

  Do not remove the capsules in blister foil

  Do not peel off the blister foil, before you have a capsule 

When removing Predaksa capsule bottle, please observe the following guidelines:

 Press and turn to open the bottle.

Usually the recommended dose is 220 mg Pradaksa QD / taken as two capsules of 110 mg /

If your kidney function is decreased by more than half, or are aged 75 years or more, the recommended dose is 150 mg once daily / taken as two capsules of 75 mg /. 

If you are taking medicines containing amiodarone or verapamil, the recommended dose is 150 mg once daily / taken as 2 capsules of 75 mg /

If you are taking medicines containing verapamil, and the function of your kidneys is reduced by more than half, you should be treated with a reduced dose of 75 mg Pradaxa because your risk of bleeding may be increased. 

After knee replacement surgery: 

You should begin treatment with Pradaxa within 1-4 hours after the operation, taking a single capsule. Then you should take 2 capsules once daily for a total of 10 days.

After hip replacement: 

You should begin treatment with Pradaxa within 1-4 hours after the operation, taking a single capsule. Then you need to take 2 capsules once daily for a total of 28-35 days.

And both surgeries should not be initiated if there is bleeding from the operation site. If treatment can not be started the day after surgery, dosing should be initiated with 2 capsules once daily. Always Pradaksa exactly as you told your doctor. If you're not sure, ask your doctor. The capsule should be swallowed with water. It should not be chewed.

Transition from treatment Pradaksa to anticoagulant treatment given by injection 

Do not start treatment with injectable anticoagulant within 24 hours after the last dose Pradaxa 

Transition from treatment given by injection to treatment with anticoagulant Pradaxa

Stop injections and then start taking pradaksa at the time should be the next injection.

POSSIBLE SIDE EFFECTS

When using Pradaxa known following common and uncommon side effects:

Common - reducing the number of red blood cells, formation of hematoma, bleeding from a wound, decreased hemoglobin in the blood oozing from the wound, bruising after surgery, bruising as a result of injury, presence of blood in urine laboratory testing

Uncommon - bleeding, bleeding in the joints, reducing the number of platelets in the blood, nose bleeding, bleeding in the stomach or bowel bleeding hemorrhoids, rectal bleeding, blood in the urine, bleeding at the catheter into the vein, variations in liver function tests, bleeding from the incision operativinya.

ADDITIONAL INFORMATION

The active substance dabigatran, which is administered as a 75 mg or 110 mg dabigatran etexilate

The other ingredients are tartaric acid, acacia, hypromellose, dimethicone 350, hydroxypropyl cellulose and talc. The capsule shell contains extract from red seaweed, potassium chloride, titanium dioxide, indigo carmine, sunset yellow, hypromellose and purified water. Black printing ink contains shellac, N-butyl alkofhol, isopropyl alcohol, industrial methylated spirit, iron oxide black, propylene glycol and purified water