QUICK HUMALOG PEN 300 IU 3 ml. 10

WHAT HUMALOG PEN AND WHAT IT IS USED
Humalog Pen used to treat diabetes. It works faster than regular human insulin because the insulin molecule has been changed slightly.
You get diabetes if your pancreas does not produce enough insulin to control the level of glucose in the blood. Humalog is a substitute for your own insulin and is used to control glucose in the long term. It works very quickly and lasts a shorter time than soluble insulin (2 to 5 hours). You should normally use Humalog within fifteen minutes before eating.
Your doctor may advise you to use Humalog Pen, as well as longer-acting insulin. Each kind of insulin with another patient information leaflet that explains its properties . Do not change your insulin unless your doctor tells you to. Be very careful if you change your insulin.
Humalog is suitable for use in adults and children. Humalog may be used in children, when an advantage is expected compared to soluble insulin, for example at the time of injection in relation to meals .

2 . BEFORE YOU USE HUMALOG PEN
Do not use Humalog Pen:
if you suspect hypoglycaemia ( low blood sugar). Later in this leaflet explains what to do with mild hypoglycaemia ;
If you are allergic (hypersensitive ) to insulin lispro or any of the other ingredients in Humalog Pen.
Take special care with Humalog Pen
If your blood sugar levels are well controlled by current insulin therapy , you may not feel the warning symptoms when blood sugar levels fall too low. Warning signs are listed later in this leaflet. Must think carefully about when to eat , how often and intensive exercise. Should carefully monitor the levels of your blood sugar by frequent measurement of blood sugar;
A few people who have had hypoglycaemia after transfer from animal insulin to human insulin have reported that early warning symptoms were less obvious or different. If you often have hypoglycaemia or have difficulty recognizing it, please discuss this with your doctor ;
If you answer "YES " to any of the following questions , tell your doctor, pharmacist or diabetes nurse :
Have you recently become ill ? ;
Do you have problems with your kidneys or liver? ;
Subjected you to more exercise than usual? ;
The amount of insulin you need may change if you drink alcohol;
You should also tell your doctor, pharmacist or diabetes nurse if you plan to travel abroad. Time difference between countries may mean that you have to have your injections and meals at different times than you are at home ;
Some patients with long-standing type 2 diabetes mellitus and heart disease or previous stroke who were treated with pioglitazone and insulin experienced the development of heart failure. Tell your doctor as quickly as possible if you experience signs of heart failure such as unusual shortness of breath or rapid increase in weight or localized swelling ( edema) .
Using other medicines
Your insulin needs may change if you take birth control pills , steroids, hormone replacement therapy thyroid , oral blood glucose lowering , aspirin , antibiotics, " sulfa " group , octreotide , " beta 2 stimulants " (e.g., ritodrine , salbutamol or terbutaline ) , beta- blockers, or some antidepressants ( monoamine oxidase inhibitors or selective serotonin reuptake inhibitors ), danazol, some angiotensin converting (ACE ) inhibitors (e.g., captopril , enalapril ), and blockers of angiotensin II receptors .

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Pregnancy and lactation
Are you pregnant or thinking about becoming pregnant , or breastfeeding ? The amount of insulin you need usually falls during the first three months of pregnancy and increases for the remaining six months. If you are breastfeeding you may need to change your insulin intake or diet. Ask your doctor.

Driving and using machines
Ability to concentrate and react may be reduced if you have hypoglycaemia. Please note this in all situations where you might put yourself and others at risk ( eg driving a car or operating machinery) . You should contact your doctor about the advisability of driving if you have:
frequent episodes of hypoglycemia ;
reduced or absent warning signs of hypoglycaemia.
 
3 . HOW TO USE PEN NUMALOG
Always check the packaging and labeling of the pre-filled pen name or type of insulin when you get it from your pharmacy. Make sure you get the Humalog Pen, who told you to your doctor.
Always use Humalog Pen exactly as your doctor tells you . If you are not sure, ask your doctor.

dosage:
You should normally inject Humalog within 15 minutes before eating . If necessary , you can inject immediately after eating. But your doctor will tell you exactly how much to use , when to use it and how often. These instructions are only for you. Follow them exactly and visit your diabetes clinic regularly ;
If you change the type of insulin you use (for example from a human or animal insulin to Humalog- ov product), you may need to take more or less than before. This may be only the first injection or it may be a gradual change over several weeks or months ;
Inject Humalog under the skin. It should be injected muscle if your doctor told you to do so .
Preparation of Humalog Pen
Humalog is dissolved in water , so you do not need to mix it . But you should use it only if it looks like water. It should be clear , colorless and without solid particles in it. Check each time you inject .
Getting the pen ready to use:
First wash your hands ;
Read the instructions on how to use pre- filled insulin pen. Please follow the instructions carefully . Here are some reminders ;
Use a clean needle. (Needles not included) ;
Prepare your pen before each use. So check that insulin comes out and clears the air bubbles from your pen. There may be still be some small air bubbles in the Pen ( pen) - they are harmless. If air bubbles are too large it may affect your insulin dose .
Injection of Humalog Pen
Before you make an injection, clean your skin as you have been instructed . Inject under the skin , as you were taught . Can not be injected directly into a vein. After your injection, leave the needle in the skin for five seconds to make sure / of that you take the entire dose . Do not rub the area you have just the injection . Make sure you inject at least half an inch (1cm) from the last injection and that you change injection sites , as you have been taught. No matter where you inject in the upper arm , thigh, buttock or abdomen , your Humalog injection will act faster than soluble human insulin ;
You must not administer Humalog intravenously. Inject Humalog as your doctor or nurse has taught you . Only your physician can administer intravenous Humalog. He will do so only under special circumstances such as surgery or if you are ill and your glucose levels are too high.
After injection:
At the moment the injection , unscrew the needle from the Pen ( pen) using the outer needle cap. This will keep the Humalog sterile and prevent leaking. It also stops air entering the Pen ( pen) and needle clogging. Do not share your needles . Do not share your pen . Put the cap back on your pen.
Further injections :
Each time you use Pen ( pen ), you must use a new needle. Before each injection , clear any air bubbles. You can see how much insulin is left by holding the Pen ( pen) with the needle pointing upwards. Graduated scale of the cartridge shows how many units of insulin left ;
Do not mix with any other insulin in your disposable pen. After Pen ( pen ) is empty, do not use it again. Please dispose of it carefully - your pharmacist or diabetes nurse will tell you how to do this .
Use of Humalog in an infusion pump
Only some insulin infusion pumps with CE mark can be used to infuse insulin lispro. Before infusing insulin lispro should study the manufacturer's instructions in order to ascertain the suitability or unsuitability of the pump. Read and follow the instructions in the product with the infusion pump ;
Be sure to use the correct reservoir and catheter for your pump ;
Change the infusion set every 48 hours. Use aseptic technique when inserting the infusion set ;
In the event of a hypoglycaemic episode , the infusion should be stopped until its removal. If repeated or severe low blood glucose levels , your doctor or clinic and consider reducing or stopping insulin infusion ;
Pump malfunction or occlusion of the infusion set may result in a rapid rise in glucose levels. If you suspect an interruption to insulin flow , follow instructions in the literature and if appropriate, notify your doctor or clinic;
When used with an insulin infusion pump , Humalog should not be mixed with any other insulin.
If you use more than the amount of Humalog
If you take more Humalog, than you need , you may experience low blood sugar. Check your blood sugar.
If your blood sugar is low, eat glucose tablets, sugar or drink a sugary drink. Then eat fruit , biscuits or a sandwich, as your doctor has advised and rest . In most cases, this will help you over mild hypoglycaemia or low insulin overdose . If you feel worse and your breathing is shallow and your skin gets pale, call your doctor. Too severe hypoglycemia can be treated with glucagon injection . Eat glucose or sugar after the glucagon injection. If you do not respond to glucagon, you will need to go to hospital. Ask your doctor to tell you about glucagon .

If you forget to use Humalog
If you use less Humalog, than you need , you may experience high blood sugar . Check your blood sugar.
If hypoglycaemia ( low blood sugar) or hyperglycemia ( high blood sugar) is not treated they can be very serious and cause headaches, nausea, vomiting, dehydration , unconsciousness, coma or even death (see A and B in section 4 . "Possible side Effects") .
Always keep spare syringes and a spare vial of Humalog, or a spare pen and cartridges, in case you lose your Pen ( pen ) or it gets damaged ;
Always carry something to show you are diabetic ;
Always carry sugar with you.
If you stop using Humalog
If you use less Humalog, than you need , you may experience high blood sugar . Do not change your insulin for you , unless your doctor tells you .

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4 . POSSIBLE SIDE EFFECTS
Like all medicines, Humalog can cause side effects , although not everybody gets them.
Local allergy is common (> 1/100 to <1 /10): Some people get redness , swelling or itching around the injection of insulin. Usually this resolves in a few days to a few weeks. If this happens to you, tell your doctor.

Systemic allergy is rare (> 1 /10, 000 to <1/ 1, 000) . The symptoms are the following :
rash all over the body ;
drop in blood pressure;
difficulty breathing ;
fast heartbeat ;
wheezy breathing ;
sweating.
If you think you have this type of insulin allergy with Humalog, tell your doctor.

Lipodystrophy (thickening or pitting of the skin ) is uncommon (> 1 /1, 000 to <1 /100) If you notice a thickening or pitting at the injection site, tell your doctor.

If any of the side effects gets serious , or you notice other effects not listed in this leaflet , please tell your doctor or pharmacist.

Common problems of diabetes
A. Hypoglycaemia
Hypoglycemia (low blood sugar ) means that there is not enough sugar in the blood. It can be caused if:
take too much Humalog or other insulin;
miss or delay meals or change your diet;
exercise or work too hard just before or after a meal;
you have an infection or illness ( especially diarrhea or vomiting);
a change in your need for insulin;
you have kidney or liver which gets worse.
Alcohol and some drugs can affect the levels of your blood sugar.

The first symptoms of low blood sugar usually come on quickly and include the following:
fatigue ;
fast heartbeat ;
nervousness or shakiness ;
feeling sick ;
headache ;
cold sweat .
While you are not confident about recognizing your warning symptoms , avoid situations such as driving in which you or others would be put at risk by hypoglycaemia .

B. Hyperglycaemia and diabetic ketoacidosis
Hyperglycemia (too much sugar in the blood) means that your body does not have enough insulin. Hyperglycemia can be caused by the fact that:
not take Humalog, designed for you or other insulin;
taking less insulin than you have been told by your doctor ;
eating a lot more than your diet allows;
fever, infection or emotional stress.
Hyperglycemia can lead to diabetic ketoacidosis. The first symptoms come on slowly over many hours or days. The symptoms include the following:
drowsiness;
lack of appetite ;
red face ;
breath smelling of fruit ;
thirst ;
feeling sick or vomiting.
Severe symptoms are heavy breathing and a rapid pulse. Seek medical help immediately.

C. Illness
If you are sick / on , especially if you feel sick or are sick / , the amount of insulin you need may change . Even when you are not eating normally, you still need insulin. Test your urine or blood, follow your 'sick rules ', and tell your doctor.

5 . HOW TO STORE HUMALOG PEN
Before use, store Humalog Pen, designed for you in a refrigerator ( 2 ° C - 8 ° C). Do not freeze.
Keep your Humalog Pen in use at room temperature ( 15-30 ° C) and discard after 28 days. Do not put it near sources of heat and light. Do not keep the pen that you are using in the refrigerator. Prefilled pen must be stored with the needle attached.
Keep out of the reach of children.
Do not use Humalog Pen after the expiry date stated on the label and carton. Expiry date refers to the last day of that month.
Do not use Humalog Pen, if it is colored or has particles in it. You can use it only if it looks like water. Check each time you inject .
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.

6 . ADDITIONAL INFORMATION
What does Humalog Pen 100 U / ml, solution for injection
The active substance is insulin lispro. Insulin lispro is made in the laboratory by a 'recombinant DNA technology' process . This is a modified form of human insulin , and therefore is different from other human or animal insulins. Insulin lispro is closely related to human insulin, which is a natural hormone produced by the pancreas .

Other ingredients are : m- cresol, glycerol, dibasic sodium phosphate 7 H2O , zinc oxide and water for injection. Sodium hydroxide or hydrochloric acid may be used to adjust the acidity .

How Humalog Pen looks like and contents of the pack
Humalog Pen 100 U / ml, solution for injection is a sterile , clear, colorless solution and contains 100 units of insulin lispro in each milliliter ( 100 U / ml) solution for injection . Each Humalog Pen contains 300 units ( 3 mL) . Humalog Pen comes in a pack of 5 pre -filled pens or a pack of 2 x 5 pre- filled pens. Not all pack sizes may be marketed . Humalog- is seen in your Pen is the same Humalog, which comes in separate Humalog cartridges . Pen ( pen) just has an integrated cartridge.