Rozoltan plus 50 mg. / 12.5 mg. 30 tablets

WHAT Rozoltan PLUS AND WHAT IT IS USED?
Rozoltan Plus is a combination of an angiotensin II receptor antagonist / losartan / diuretic / hydrochlorothiazide /

Rozoltan Plus is indicated for the treatment of essential hypertension.

BEFORE TAKE ROZOLTAN PLUS
Do not take Rozoltan Plus
- If you are allergic to losartan, hydrochlorothiazide or any other ingredients of this medicine
- If you are allergic to other drugs known as sulfonamide derivatives
- If you have severely impaired liver function
- If you are more than 3 months pregnant
- If you have severely impaired kidney function or your kidneys do not produce urine
- If you have low potassium, low sodium or high calcium levels which can not be corrected with treatment.
- If you suffer from gout

Be careful when taking Rozoltan Plus
- If you have a swollen face, lips, throat or tongue
- If you are taking diuretics
- If you have or have had severe vomiting and / or diarrhea
- If you have heart failure
- If you have narrowing of the renal arteries or only have one functioning kidney, or you have recently had a kidney transplant
- If you have narrowing of the arteries, angina
- If you have 'aortic or mitral stenosis "or" hypertrophic cardiomyopathy "
- If you suffer from diabetes
- If you have gout
- If you are going anesthesia or surgery, or if you are going to paratirodnata feature, you should tell your doctor that you are taking losartan potassium tablets and hidrohloritiazid.

It is important for your doctor to be informed if you are taking:
- Other medicines to lower your blood pressure
- steroids
- Anticancer drugs
- painkillers
- Medicines against fungal infections
- Medicines against arthritis
- Resins used for high cholesterol
- Medicines that relax muscles
- hypnotics
- Opioid drugs such as morphine


Adoption of Razoltan PLUS FOOD AND BEVERAGES
It is advisable not to consume alcohol while taking these tablets: alcohol and Rozoltan Plus can mutually reinforce their effects.
Dietary salt in excessive quantities may counteract the effect of Rasoltan Plus.
Rozoltan Plus can be taken with or without food.

Pregnancy and lactation
Consult your doctor before taking any medication.
You need to tell your doctor if you think you are pregnant. Usually the doctor will advise you to stop taking Rozoltan Plus before you become pregnant or as soon as pregnancy and start taking another medicine instead Rosaltan Plus. Not recommended intake of Rasoltan Plus in early pregnancy, and after the third month of pregnancy because the drug can cause serious harm to your baby if taken after the third month of pregnancy.

breastfeeding
Not recommended intake of Razoltan Plus mothers who breastfeed, so your doctor may choose another drug while breastfeeding, especially Oka baby is newborn or preterm.

Use in children and adolescents
There is no experience with the use of Rasoltan Plus in children. Therefore Rasoltan Plus should not be used in children.

Use in Elderly
Rosaltan Plus there are equally good effect and equally well tolerated by both elderly and younger patients.

Driving and using machines
When you start treatment with this medicine, you should not perform tasks that require special attention until you know what your tolerance to the drug.

HOW TO TAKE Rozoltan PLUS?
High blood pressure
The usual dose for most patients with high blood pressure is 1 tablet Rasoltan Plus 50 mg / 12.5 mg per day for control of blood pressure for a period of 24 hours. The dose may be increased to 2 tablets once a day. The maximum daily dose is two tablets a day.

If you take more than the amount
Overdose can cause a drop in blood pressure, palpitations, slow pulse, changes in blood composition and dehydration.

If you miss
If you miss a dose, do not take extra dose. Just resume normal pattern of ingestion.

POSSIBLE SIDE EFFECTS:
The occurrence of these reactions, stop taking Rosaltan Plus and tell your doctor immediately or go to the nearest hospital.

Severe allergic reaction / rash, itching, swelling of the face, lips, mouth or throat that may cause difficulty in swallowing or breathing /.

Reported the following adverse reactions:
- Cough, infection of the upper respiratory tract, nasal congestion, sinusitis, sinus disorder
- Diarrhea, abdominal pain, nausea, dyspepsia
- Muscle pain or cramps, leg pain, back pain
- Insomnia, headache, dizziness
- Weakness, fatigue, chest pain
- Elevated potassium levels

Uncommon:
- Anemia, red or brownish spots on the skin, bruising, reduction in white blood cells, clotting problems and injuries
- Loss of appetite, increased levels aan uric acid or gout, increased blood sugar levels, abnormal levels of electrolytes in the blood
- Anxiety, nervousness, panic disorder, confusion, dipresiya, sleep disturbance, drowsiness
- Numbness, pain in the limbs, tremors, migraines, seizures
- Blurred vision, burning or stinging in the eyes, conjunctivitis, low vision, vision yellow
- Ringing, buzzing, roaring or clicking in the ears
- Low blood pressure, abnormal heartbeat, cerebrovascular accident, heart attack, heart palpitations
- Inflammation of the blood vessels which is often associated with skin rash or bruising
- Sore throat, shortness of breath, bronchitis, pneumonia, water in the lungs
- Constipation, gas, dyspepsia, vomiting, dry mouth, toothache
- jaundice
- Hives, itching, skin inflammation, rash, redness of the skin
- Pain in the arms, shoulders, hips, joint swelling, stiffness, muscle weakness
- frequent urination
- Decreased sex drive, impotence

rare:
Hepatitis, abnormal liver function

MORE INFORMATION:
What:
The active substances are losartan potassium and hydrochlorothiazide
The other ingredients are:
Tablet core: mannitol, cellulose, microcrystalline, croscarmellose sodium, povidone, magnesium stearate
Tablet film coating: hypromellose, hydroxypropyl cellulose, titanium dioxide, Macrogol 400