SIMVAKOR table. 40 mg. 30 tablets

SIMVAKOR WHAT IS AND WHAT IT IS USED

Simvakor was coated tablet containing 10, 20 or 40 mg simvastatin as an active ingredient.

Furthermore, Simvakor contains the following inactive ingredients: butylated hydroxyanisole, ascorbic acid, citric acid monohydrate, microcrystalline cellulose, pregelatinized starch, magnesium stearate, lactose, hypromellose, hydroxypropyl cellulose, titanium dioxide, talc, red iron oxide.

Simvakor is available as film-coated tablets of 10, 20 or 40 mg in packs of 30 tablets.

Simvakor lowers LDL - C (bad cholesterol) and the fats called triglycerides in the blood and increases levels of NDL-C (good cholesterol). It belongs to a group of drugs known as inhibitors hidroksimetilglutaril-Coenzyme A (CoA NMG). Your doctor has prescribed Simvakor to reduce health risks associated with coronary heart disease (CHD).

If you have coronary artery disease, diabetes, previous stroke, or have other vascular disease (regardless of cholesterol in your blood) Simvakor can:

 Extend your life by reducing the risk of heart attack or stroke

 Reduce the need for surgery, increasing blood flow to the legs and major organs like the heart

 Reduce the need for hospitalization due to chest pain (called angina)

Simvakor reduces the amount of cholesterol in the blood. Cholesterol can cause ischemic heart disease (IHD), clog the blood vessels that carry oxygen and nutrients to the heart. Clogging or hardening of the arteries is called atherosclerosis. Atherosclerosis can cause chest pain (called heartwater) and heart attack.

Simvakor also slows the progression of atherosclerosis and reduces the development of a new one.

High cholesterol is the result of a number of factors, such as the use of foods rich in saturated fats, certain diseases or genetically-determined conditions and lack

sufficient physical activity. Lowering cholesterol may reduce the risk of developing CHD.

A number of reasons can lead to coronary artery disease.

To develop CHD risk may increase if there are several factors:

 High Cholesterol

 High blood pressure

 Smoking

 Diabetes

 Obesity

 Family history

 male

 Period after menopause

To you to control the first five of these reasons that lead to coronary artery disease.

What can you do to save the longer your health and reduce your risk of developing coronary artery disease?

  Stop smoking!

Smoking increases the risk of heart attack.

  Exercise!

This will increase the level of "good" cholesterol and reduce the risk of developing CHD.

Ask your doctor before you start playing sports. Visit your doctor regularly! Your doctor will monitor your cholesterol levels. Take your medicine regularly! Do not stop your treatment to keep under control your cholesterol level. Follow the diet recommended by your doctor! The diet will not only help to lower cholesterol, but also losing weight (if necessary).

LDL - cholesterol is called "bad" cholesterol because it causes this type of cholesterol clogging the arteries.

HDL - cholesterol, on the other hand, is believed to remove cholesterol from the blood vessels and is therefore perceived to be called "good" cholesterol.

Simvakor exerts its effect by reducing the production of cholesterol in the liver (the main source of cholesterol in the body) and increase the rate of removal of cholesterol from your bloodstream by the liver. In view of the existence of LDL and HDL, Simvakor significantly reduced LDL ("bad" cholesterol) and most patients increases HDL ("good" cholesterol). By combining Simvakor with dieting, you take control of the amount of cholesterol that your diet and the amount that your body produces.

For most people, with high cholesterol do not appear as symptoms. Your doctor can measure the amount of cholesterol in the blood by a simple blood test. Visit your doctor regularly to keep track of your cholesterol level and discuss the results with him.

 BEFORE YOU TAKE SIMVAKOR

Do not take Simvakor:

 if you are allergic to simvastatin or any of the other ingredients of Simvakor

 If you have a confirmed diagnosis of active liver disease

 if you are pregnant or breast-feeding

Simvakor not recommended for use in children under 18 years.

Take special care with Simvakor

Tell your doctor about any medical problems you have or have had in the past and existing allergies. Tell your doctor if you consume large amounts of alcohol and if you have had liver disease.

If in doubt, consult your doctor or pharmacist.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. It should also tell any doctor who prescribes a new drug therapy that take Simvakor.

Since taking Simvakor with the following medicines may increase the risk of muscle problems (see what side effects may occur due to use of Simvakor) is especially important to tell your doctor if you take:

 cyclosporine

 antifungal agents (eg itraconazole or ketoconazole)

 fibric acid derivatives (such benzafibrat, fenofibrate and gemfibrozil)

 antibiotics erythromycin and clarithromycin

 HIV protease inhibitors (such as indinavir, nelfinavir, ritonavir, sakuinavir)

 amiodarone (a drug to treat cardiac arrhythmias)

 Verapamil (a medicine to treat high blood pressure or angina)

 High doses (more than 1 g per day) of niacin or nicotinic acid

It is also important to tell your doctor if you are taking anticoagulants (drugs that prevent blood clots, such as warfarin, phenprocoumon or atsenokoumarol).

Pregnancy and lactation:

Ask your doctor or pharmacist before taking any medicine. Simvakor should not be used in pregnant women and women intending to become pregnant or those who are supposed to be pregnant. If you become pregnant burden of treatment Simvakor, immediately stop using the drug and consult a doctor. Women undergoing treatment with Simvakor should not breastfeed.

Driving and operating machinery

There is no evidence to suggest that simvastatin affects your ability to drive or use machines.

 HOW TO TAKE SIMVAKOR

Always Simvakor exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist. The doctor has prescribed your dose Simvakor. The usual starting dose is 20 mg or 40 mg daily as a single dose appointed evening. Your doctor can determine the dose to 80 mg daily as a single dose appointed evening. He can prescribe the drug in lower doses, especially when you are taking cyclosporine or suffer from any kidney disease. Do not stop your treatment with Simvakor until your doctor determines that you have to stop it. Upon discontinuation of Simvakor, cholesterol levels will rise again.

Simvastatin is contraindicated in children and adolescents under 18 years of age.

If you take more than the dose Simvakor

If you or someone else has taken a great deal Simvakor, tell your doctor or pharmacist. Take the medicine pack with you.

If you forget to take Simvakor

Try to take Simvakor as prescribed. If you forget to take a dose, do not take a double dose to make up for lost. Just resume your usual regimen.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

 POSSIBLE SIDE EFFECTS

Like all medicines, Simvakor can cause side effects, although not everybody gets them. Simvakor generally well tolerated. Most side effects are mild and transient. The most common side effects are indigestion, dizziness, blurred vision, headache or rash. A paucity of muscle pain, weakness or faint, liver complaints and hypersensitivity (allergic reaction that can involve various symptoms such as joint pain, fever and shortness of breath.) Since muscle problems, though rare, can be serious if you experience muscle pain, weakness or faint, immediately consult your doctor.

Tell your doctor if you experience unusual symptoms or if you are already a symptom does not recover or get worse.

If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

 HOW TO STORE SIMVAKOR

 Keep out of reach of children.

  Do not store above 25 ° C.

  Do not use Simvakor after the expiry date stated on the carton. The expiry date refers to the last day of that month.

 Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

 ADDITIONAL INFORMATION

What Simvakor

  The active substance is simvastatin.

 Other ingredients: butylated hydroxyanisole, ascorbic acid, citric acid monohydrate, microcrystalline cellulose, pregelatinized starch, magnesium stearate, lactose, hypromellose, hydroxypropyl cellulose, titanium dioxide, talc, red iron oxide.