SOLU-MEDROL 40 mg.

What is SOLU-MEDROL?
The name of your medicine is SOLU-MEDROL. Drug is methylprednisolone (methylprednisolone). SOLU-MEDROL contain 40 mg, 125 mg, 250 mg, 500 mg, 1000 mg or 2000 mg methylprednisolone in the form of powder, solution for injection.
SOLU-MEDROL also contains excipients: the powder contains sodium dihydrogen phosphate monohydrate, disodium phosphate, and in the packaging of 40 mg contains lactose. The solvent contains benzyl alcohol and water for injection.
 

What is the action of SOLU-MEDROL?
SOLU-MEDROL belongs to a group of medicines called corticosteroids or steroids. Corticosteroids are hormones which are produced naturally by the adrenal glands, which are located above the kidneys. They help the body deal with inflammation, allergic reactions and other stress conditions. This drug is a synthetic corticosteroid, similar to the natural hormone, and have the same effect.
SOLU-MEDROL has two main steps: First, it interrupts inflammation (pain, swelling, redness and warmth) in your body. Another effect is a decrease in activity of the immune system. This is useful, for example in conditions in which the immune system attacks its own body of the patient (an autoimmune response), causing damage to, or when causing a strong reaction to the substance with which the patient is contacted (eg. An allergy).
SOLU-MEDROL not "anabolic steroid" for weight gain.

producer
Pfizer
 
What is SOLU-MEDROL
Your medicine may be used for treatment of:
• Hormonal disorders: eg., If the adrenal glands are not working properly for some reason, so that the body does not produce enough of its own natural steroids; shock adrenal insufficiency or shock unresponsive to standard treatment, which may have only failure of adrenal cortex; in patients who have surgery have severe trauma or other disease combined with adrenal insufficiency or adrenal suspicious reserves; xipepkaltsiemiya (povisheni levels of calcium in the blood) in relation to cancer; negnoen thyroiditis (inflammation of the thyroid gland); excessive growth in congenital adrenal glands.
• Rheumatic diseases: rheumatoid arthritis inflammation affecting the joints and / or other parts of the body in adults or children; acute and subacute bursitis (inflammation of periarticular bag), acute nonspecific tenosynovitis (inflammation of the vagina muskulnosuhozhilie), acute gouty arthritis (inflammation of the joints in gout), posttraumatic osteoarthritis (joint inflammation after injury), synovitis in osteoarthritis (inflammation of any joint mucosa), epicondylitis (inflammation of the terminal portion of some bones). It is used as adjunctive therapy in ankylosing spondylitis (ligaments of the spine and pelvis ossification and coalesce with each other), psoriatic arthritis (joint inflammation in psoriasis).
• collagen, muscle inflammation (such as dermatomyositis or polymyositis); systemic lupus erythematosus (rash accompanied by fever, arthritis, inflammation of the blood vessels, kidney disorders and disorders affecting the brain); remavmatichen acute carditis (affecting the heart muscle rheumatism); other disorders such as poliarteriitis nodosa or Goodpasture's syndrome.
• Skin diseases: pemphigus vulgaris (blisters on the skin), other skin diseases (bullous dermatitis herpetiformis or seborrheic dermatitis, severe psoriasis, severe erythema multiforme (Syndrome Stevens-Johnson), exfoliative dermatitis, mukozis fungoides).
• Allergic conditions: asthma; severe forms of hay fever and other allergies, accompanied by fever; allergies to certain drugs (such as penicillin) and serum sickness (allergy vaccines produced from animal serum); skin allergy due to contact with certain substances (contact dermatitis), edema of the larynx and the like.
• Eye diseases: iritis or iridocyclitis (inflammation of the front of the eye); posterior uveitis (inflammation of the back of the eye); optic neuritis (inflammation of the optic nerve), inflammation of the anterior segment, allergic conjunctivitis or allergic corneal ulcers edge and other ocular diseases (herpes zoster ophthalmicus, chorioretinitis, keratitis).
• Intestinal diseases ulcerative colitis (inflammation and ulceration of the colon); Disease Crohn (inflammation of the different parts of the intestine).
• Lung inflammation, pulmonary sarcoidosis (inflammation of the tissues and the lymphatic glands of the lungs); tuberculosis, which progresses rapidly or has spread to other areas (both with anti-tuberculosis drugs); inflammation caused by aspiration of gastric contents or vomit into the lungs when the unconscious; moderate to severe pneumonia caused by Pneumocystis carinii in patients with AIDS (such as add-on therapy) and other pulmonary diseases (berylliosis and Loeffler's syndrome).
• Blood disorders: idiopathic thrombocytopenic purpura (increased tendency to bruising and bleeding due to low number of blood cells that help blood clotting) in adult secondary thrombocytopenia (low number of blood cells that help blood clotting); autoimmune hemolytic anemia (when the immune system attacks its own red blood cells) and other anemias.
• Malignancies: Leukemia (excessive formation of white blood cells in the bone marrow); cancer of the lymphatic system, which usually affects the lymph nodes (glands) and spleen; improving the quality of life in cancer patients in the end stage.
• swollen conditions: to increase diuresis (urine excretion) in nephrotic syndrome (kidney disease).
• Other conditions: multiple sclerosis; TB infection causing inflammation of the meninges (lining of the brain), together with anti-tuberculosis agents; brain edema caused by a tumor; Early treatment of spinal cord injury; organ transplantation; Prevention of nausea and vomiting in cancer treatment.
Your doctor could apply SOLU-MEDROL to treat conditions other than those listed above. Ask your doctor if you are unsure of the reason why he giving it to you.
Is the SOLU-MEDROL in your case?
Your doctor will ask you questions before prescribing this medicine, make sure that it is suitable for you. If you do not understand any of the questions, ask your doctor to explain them to you.
You should not take this medicine if:
• you have had an allergic reaction such as skin rash, swelling, wheezing or breathing problems after taking the SOLU-MEDROL, methylprednisolone, a glucocorticoid or any of the ingredients in this medicine;
• have widespread (systemic) fungal infection.
Tell your doctor if any of the above events apply to your case.
If you answer "YES" or are not sure about the answer, talk to your doctor. Your doctor may want to follow more closely your condition or may decide that treatment with Thessaloniki-MEDROL not be suitable for you.
• Are you pregnant; is there a possibility that you are pregnant? Do you trying to conceive? You must use effective contraception and not trying to become pregnant before the drug is transmitted from your body. If this medicine you will be given during pregnancy, your baby is subject to further research soon after birth to determine whether his adrenal glands are working normally. Remind them to your doctor.
• Breast milk it? If you continue to breast-feed during treatment, your baby will be further research to see if the drug did not have any influence on it.
• Do you have liver failure or cirrhosis (in these cases there may be yellowing of the skin or jaundice)?
• Do you have kidney problems (leading to increased or decreased urine output)?
• Do you suffer from high blood pressure?
• Do you have heart failure (you have swollen ankles, shortness of breath and palpitations)?
• Do you hypoprothrombinaemia (disease associated with reduced blood clotting)?
• Do you have problems with the digestive tract, such as ulcers of the stomach or intestines (can lead to stomach pain, even if you do not worry at the moment), diverticulitis (inflamed pockets in the inner wall of the digestive tract, causing left-sided abdominal pain, constipation or diarrhea ) or ulcerative colitis (swelling and ulceration of the gut)? Although steroids are very effective for the treatment of inflammation in ulcerative colitis, they can also increase the risk of bleeding or perforation (tearing) of the ulcerated intestine.
• Are you soon stomach surgery, appendix, gall bladder, pancreas or small or large intestine?
• Do you have you or someone in your family diabetes (problems with balance sugar) or glaucoma (increased eye pressure)?
• Do you have osteoporosis (brittle bones)?
• Do you have myasthenia gravis (when some or all of your muscles are affected by weakness or tire easily)?
• Have you ever myopathy (muscle problems weakness or pain, especially in the lower extremities and buttocks) when treated with steroids?
• Do you have suffered and you ever from mental illness (eg, emotional instability, depression, hallucinations)? If before you are being treated with steroids,
Is it cause psychosis (mental illness, which was to be conducted on an outpatient or inpatient treatment)?
• Do you have abscesses?
• Do you currently have any infections?
• Have you ever had an eye infection caused by herpes simplex virus? Do you currently ocular herpes (ulcers of the eye that has emerged recently, or inflammation of the eye)?
• Do you have tuberculosis? Have you ever suffered from tuberculosis in the past? Did you test positive for tuberculosis?
• Will you be vaccination Are you a recent vaccination? (Tell your doctor or nurse that you are taking SOLU-MEDROL if you require vaccinations. During treatment with this medicine should not receive live vaccines and other vaccines may be less effective).
• This medicine contains benzyl alcohol. There is evidence that benzyl alcohol can lead to fatal "gasping-syndrome" (respiratory disorder characterized by prolonged difficulty / respiratory arrest) in premature infants.
Be sure to tell your doctor if you have any of these problems before starting treatment with this medicine.
If you must do some research, notify your doctor that you are taking SOLU-MEDROL.
 
Are you taking other medicines?
Methylprednisolone may interact with some drugs.
Before starting treatment with Thessaloniki-MEDROL tell your doctor if you are taking other medicines, including medicines you bought yourself.
If you are already taking SOLU-MEDROL, tell your doctor immediately if you are taking and any of the drugs listed below.
Tell your doctor if you are being treated for diabetes (high blood sugar), high blood pressure or heart failure. This medicine can make treatment less effective. This means that it may be necessary for your doctor to change the dose of these drugs.
Make sure to tell your doctor if you are taking any of the medicines listed below:
• Some antibiotics (eg. Troleandomycin) or antifungal drugs (eg., Ketoconazole), and some calcium antagonists (drugs for the treatment of hypertension or angina) can decrease methylprednisolone from the body, and therefore it is necessary to more carefully dosing SOLU-MEDROL;
• drugs, that lead to the activation of hepatic enzymes (such as phenobarbital, phenytoin, rifampicin) can increase the release of methylprednisolone from the body, and therefore it is necessary to increase the dose of SOLU-MEDROL to achieve the desired response.
• Anticoagulants (medicines that inhibit blood clotting);
• Aspirin and similar drugs called salicylates (used usually in pain and / or inflammation in temperature). Methylprednisolone enhances emission of aspirin and related drugs (called salicylates) from the body. If you stop taking the SOLU-MEDROL, their concentrations can suddenly increase and cause side effects such as tinnitus. If you hypoprothrombinaemia (increased bleeding), your doctor will be more cautious if you need to prescribe steroids simultaneously with aspirin or salicylates.
• Cyclosporin - this is a drug called "immunosuppressant" which is used to suppress the immune system in patients with severe rheumatoid arthritis, severe psoriasis or patients who have had a transplant organ or bone marrow.
If you are not sure if any of the medicines you take, included in the above list, ask about your doctor, nurse or pharmacist. If you visit your doctor
occasion of another medical problem, remind him that taking SOLU-MEDROL.
 
specific issues
infections
SOLU-MEDROL may mask some signs of infection, reduce your resistance to infection and to modify the signs and symptoms of infection so that they become difficult to diagnose in its early stages. It also increases the likelihood of developing a serious infection. If you think you have an infection, report it immediately to your doctor.
tuberculosis
SOLU-MEDROL applies only when tuberculosis is very advanced or has spread throughout the body with the aim of halting the disease process simultaneously with appropriate anti-tuberculosis agents. If you have ever suffered from tuberculosis in the past or if you test positive for TB, your doctor will closely monitor whether TB will not appear again. He may prescribe anti-tuberculosis agents to prevent this possibility.
Use in children
Growth may be suppressed in children receiving long-term glucocorticoids treatment with a daily dose in divided doses. The implementation of such a scheme should be restricted to those most serious indications.
 
How to apply SOLU-MEDROL?
Your doctor will decide what dose you should receive. The amount depends on your illness and its severity. Your doctor will always endeavor to apply the lowest possible dose that leads to a good result. Always take your medicine exactly the way your doctor appointed him. If you are unsure, ask your doctor, nurse or pharmacist.
Your doctor may prescribe a higher dose for a few days to control your condition. If your condition is not controlled, it can change treatment. It is possible that your doctor makes frequent inspections to ensure that you feel better. If SOLU-MEDROL was appointed because your body is unable to produce its own corticosteroids, your doctor may also prescribe a second type of steroid to help salt balance.
The initial dose chosen by your doctor will be continued until he decides that your condition has improved. If the doctor finds that your condition has improved, it will gradually reduce the dosage.
The drug can be administered as intravenous and intramuscular injection.
 
Use in children
SOLU-MEDROL may be prescribed for children. Usually prescribed a lower dose than that of adults, but it depends on the severity of the condition and response to treatment.
What to do if you received a higher dose or if you miss a dose
Since this medication is given by injection under medical supervision, likely to miss a dose or get a larger dose is small. If in doubt, consult your doctor.
Stopping the drug / dose reduction
Your doctor will decide when it is time to stop treatment.
Treatment with SOLU-MEDROL should not be stopped abruptly, but with gradual dose reduction, as will determine your doctor. This is because too rapid reduction in steroid dose can lead to acute adrenal insufficiency (your adrenal glands do not produce enough corticosteroids own), very low blood pressure (causing dizziness and fainting) and potentially fatal. This is more likely to happen when they were received repeated doses.
If you think your symptoms returned while reduction of SOLU-MEDROL, report it to your doctor as soon as possible. If you get an infection, have an accident or need surgery, you may need to temporarily increase the dose. If you stop taking the medicine just before infection, injury or surgery, you may need to re-start taking it for a short time.
Dose changes remind your doctor about all other medicines you are taking, especially drugs such as aspirin. Remember also that you need to report any doctor who see you later that you had in the past SOLU-MEDROL.