SUZASTOR 10 mg. 30 tablets

WHAT SUZASTOR AND WHAT IT IS USED
Suzastor belongs to a group of medicines called statins (inhibitors of HMG-CoA reductase).

Suzastor is prescribed to you as:
You have elevated cholesterol. This means that you are at risk of heart attack or stroke.
Recommended you take a statin, because changing your diet and performing more exercise were not enough to correct cholesterol levels in you. You should continue your diet and exercise to lower cholesterol while taking Suzastor.

or
There are other factors that increase the risk of heart attack, stroke or other related health problems.
Heart attack, stroke and other problems can be caused by a condition called atherosclerosis. Atherosclerosis due to the accumulation of fatty deposits in the arteries.

Why is it important to continue taking Suzastor?
Suzastor is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol.
There are different types of cholesterol in the blood - 'bad' cholesterol (lipoprotein cholesterol or low-density LDL cholesterol) and "good" cholesterol (cholesterol lipoprotein, high density or HDL cholesterol).
Suzastor can reduce levels of "bad" cholesterol and increase levels of good cholesterol;
Its action consists in this, that helps block the formation of "bad" cholesterol in your body and improves your body's ability to remove it from your blood.
For most people, high cholesterol does not affect the way in which they feel because they do not cause any symptoms. However, if cholesterol is not treated, the walls of your blood vessels can form fatty deposits and so they will narrow.
Sometimes narrowed blood vessels can become blocked and this will stop the flow of blood to the heart or brain, leading to heart attack or stroke. By lowering your cholesterol levels, you can reduce the risk of heart attack, stroke or other related health problems.
We need to continue taking Suzastor even if your cholesterol has reached the normal values, as this drug prevents new increase your cholesterol. However, you should stop if your doctor tells you or if you become pregnant.

2. BEFORE YOU TAKE SUZASTOR
Do not take Suzastor:
if you are allergic (hypersensitive) to rosuvastatin or any of the other ingredients of Suzastor;
if you have liver disease;
if you have severe kidney disease;
If you have repeated or unexplained muscle pain or painful sensations (myopathy);
if you are taking a drug called cyclosporine (used eg after an organ transplant);
if you are pregnant or breast-feeding (see. section "Pregnancy and lactation"). If any of these apply to you (or you are experiencing doubt), consult your doctor.
Take special care with Suzastor:
If you have kidney problems;
if you have liver problems;
if have severe belodrobna failure;
If you have repeated or unexplained muscle pain or painful sensations (myopathy), personal or family history of muscle problems or if you have a history of muscle problems when taking other drugs to lower cholesterol. Tell your doctor immediately if you experience unexplained muscle pain or painful sensations, and especially if you feel unwell or fever;
if you regularly consume large amounts of alcohol;
if your thyroid gland is not functioning properly;
if you take other medicines called fibrates to lower your cholesterol;
if you take medicines against HIV infection (eg, lopinavir, ritonavir), see. section "Taking other medicines";
if you are aged over 70 (as your doctor needs to choose the right starting dose Suzastor to your needs);
if you are of Asian origin (that is Japanese, Chinese, Filipinos, Vietnamese, Koreans and Indians). Your doctor needs to choose the right starting dose Suzastor to your needs;
If the patient is under 10 years of age: Suzastor should not be given to children under 10 years;
If the patient is under 18 years of age: 40 mg of Suzastor is not suitable for use in children and adolescents under 18 years of age.
If any of the described above applies to you (or you are not sure):
Consult your doctor or pharmacist before you start taking rosuvastatin.
In a few people, statins can affect the liver. This is established by a test that examined the levels of liver enzymes in the blood. Therefore your doctor will do as usual this blood test (liver function test) before and during treatment with Suzastor.

Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those you take without a prescription.

Tell your doctor if you are taking any of the following medications:
ciclosporin (used eg after an organ transplant);
warfarin or any other medication to thin the blood;
fibrates, and other products for lowering lipids (such as gemfibrozil, fenofibrate);
any other medicine to lower cholesterol (such as ezetimibe)
treatments for indigestion (used to neutralize acid in your stomach);
erythromycin (antibiotic);
oral contraceptive (pill to prevent pregnancy);
hormone replacement therapy or lopinavir and ritonavir (to treat HIV infection).
Please see "Take special care with Suzastor." Suzastor may change the action of these drugs, or they may change the action of Suzastor.

Taking Suzastor with food and drink
It can take Suzastor with or without food.

Pregnancy and lactation
Suzastor not take if you are pregnant or breast-feeding. If you become pregnant while taking Suzastor should immediately stop taking the medication and tell your doctor. Women should avoid becoming pregnant while taking Suzastor using appropriate means of contraception.

Driving and using machines
Most people can not drive or operate machinery while taking Suzastor because the drug does not affect their ability to do so. However, some people feel dizzy during treatment with Suzastor. If you feel dizzy, consult your doctor before driving or using machinery.

Important information about some of the ingredients of Suzastor
If your doctor has told you have an intolerance to some sugars (lactose or milk sugar), you should consult with your doctor before taking Suzastor.

3. HOW TO TAKE SUZASTOR
Before starting treatment, your doctor will put you on a diet to lower cholesterol, which should continue during therapy.
Your doctor will decide which is most appropriate dose for you.
Always take Suzastor just as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.

Usual doses in adults
If you take Suzastor for high cholesterol:
initial dose
Your treatment with Suzastor should start with a dose of 5 mg or 10 mg, even if you have received a higher dose of another statin. The choice of your initial dose will depend on:
The dose depends on:
your cholesterol;
the level of risk of heart attack or stroke in you;
whether you are at factor that makes you more sensitive to possible side effects.
Please consult your doctor or pharmacist what starting dose of Suzastor is most suitable for you.

Your doctor may decide to prescribe the lowest dose (5 mg), if:
are of Asian origin (Japanese, Chinese, Filipinos, Koreans and Indians);
you are over 70 years;
you have moderate kidney problems;
It is at risk of muscle pain or painful sensations (myopathy).
Increasing the dose and maximum daily dose
Your doctor may decide to increase your dose. This is about taking Suzastor dose that is right for you. If zapochnete a dose of 5 mg, your doctor may decide to double to 10 mg, and then to 20 mg and then 40 mg, if needed. If you started with 10 mg, your doctor may decide to double the dose to 20 mg and then to 40 mg, if necessary. Between each dose adjustment is made 4-week break. Suzastor maximum daily dose is 40 mg. It is only for patients with high cholesterol levels and increased risk of heart attack or stroke in which cholesterol can be lowered enough dose of 20 mg.

If you take Suzastor to reduce the risk of heart attack, stroke or related health problems:
The recommended dose is 20 mg daily. However, your doctor may decide to use a lower dose if you have any of these factors mentioned above.

Usual doses in children aged 10 - 17 years
The usual starting dose is 5 mg. Your doctor may increase your dose to the most appropriate dose Suzastor for you. The maximum daily dose of Suzastor is 20 mg. Take your dose once a day.

Taking Tablet
Swallow each tablet whole with water.
Take Suzastor once a day. You can take it at any time of day. Try to take the tablet at the same time each day to help you remember.

Regular cholesterol tests
It is important to go to your doctor for regular cholesterol tests to make sure your cholesterol has reached and remained in the normal range.
Your doctor may decide to increase your dose to take the amount of Suzastor which is suitable for you.

If you take more than the amount Suzastor
Talk to your doctor or nearest hospital.
If you go into a hospital or you treat another illness, tell the medical staff that you are taking Suzastor.

If you forget to take Suzastor
Do not worry, just take your next scheduled dose at the right time. Do not take a double dose to make up for a missed tablet.

If you stop taking Suzastor
Consult your doctor if you want to stop taking Suzastor. Your cholesterol levels may increase again if you stop taking Suzastor.

If you have any questions about using this medicine, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Suzastor can cause side effects, although not everybody gets them.
It is important to be aware of what can be these side effects. They are usually mild and disappear after a short period of time.

Stop taking Suzastor and immediately seek medical help if you have any of the following allergic reactions:
difficulty breathing with or without swelling of the face, lips, tongue and / or throat;
swelling of the face, lips, tongue and / or throat that may cause difficulty in swallowing;
severe itching of the skin (blisters).
Furthermore, stop taking Suzastor and immediately tell your doctor if you experience unusual pain or painful sensations in muscles that keep a long time. Muscle symptoms are more common in children and adolescents compared to adults. As with other statins, very few people experience unpleasant effects in muscles, they seldom last long and become potentially life-threatening muscle breakdown called rhabdomyolysis.

Common possible side effects (may affect between 1 in 10 and 1 in 100 patients):
headache;
dizziness;
constipation;
malaise;
stomach ache;
muscle pain;
a feeling of weakness;
diabetes, particularly those with blood sugar at the upper end of the normal range.
Uncommon possible side effects (these may affect between 1 in 10 to 1 in 1000 patients):
rash, itching or other skin reactions;
increased amount of protein in the urine (abnormal test results of kidney function) - usually returns to normal on its own without having to stop taking your tablets Suzastor.
Rare possible side effects (these may affect between 1 in 10 to 1 in 10,000 patients):
serious allergic reaction - signs include swelling of the face, lips, tongue and / or throat, difficulty swallowing and breathing, severe itching of the skin (blisters). If you think you have an allergic reaction, stop taking Suzastor and seek immediate medical care;
muscle damage in adults - as a precaution, stop taking Suzastor and immediately consult your doctor if you have unusual pain or painful sensations in muscles that continue for a long time;
severe stomach pain (inflammation of the pancreas);
elevated liver enzymes in the blood.
Very rare possible side effects (these may affect less than 1 in 10,000 patients):
jaundice (yellow skin and eyes);
hepatitis (inflammation of liver);
traces of blood in your urine;
damage to the nerves in the feet and your hands (such as perception);
joint pain;
memory loss.
Side effects of unknown frequency include:
diarrhea (loose stools);
Stevens-Johnson (severe blistering of the skin, mouth, eyes and genitals);
cough;
shortness of breath;
edema (swelling);
sleep disorders, including insomnia and nightmares;
sexual dysfunction;
depression;
problems related to breathing, including persistent cough and / or dyspnea or fever.
If any of the side effects become bothersome or experience other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE SUZASTOR
Keep out of reach of children.
Do not use Suzastor after the expiry date stated on the carton and blister. The expiry date refers to the last day of that month.
Store in the original container to protect from moisture. The shelf life after opening the HDPE bottle is up to three months.