TALITON 12.5 mg. 30 tablets

WHAT TALITON AND WHAT IT IS USED
Toliton (korvedilol) belongs to a group of medicines called beta-blockers and neselekgiven. It extends kravonsanite containers, but due to the selective inhibition of alpha-1 receptors.
Indications: Taliton tablets are used for long-term treatment of chronic heart failure, high blood pressure and chronic stable angina (chest pain caused by disease but arteries of the heart).
This drug should not be used for mastering but stenokorden attack.

2. BEFORE YOU TAKE TALITON
Do not take tablets Taliton
Before you start taking this medicine, tell your doctor if you have or have ever had any of the following:
if you are allergic (svrahchuvstvntelni) to carvedilol or any of the other ingredients of Taliton tablets;
severe heart failure;
cardiac conduction abnormalities (syndrome sick sinus, sinus-atrial block, II or III degree atrioventricular block) unless you have a pacemaker eye (artificial heart rigam leader);
bradycardia (low heart rate below 50 beats per minute); hypotension (low blood pressure, upper limit below 85 mm Hg);
disease of the airways, difficulty breathing, chronic heart disease from lung origin, bronchial asthma or otherwise;
feohromotsitam (except a tumor of the adrenal gland);
liver disease;
prolonged treatment with medications such as MAO inhibitors (moclobemide noprimer) unless polling MAO-B nnhibigori (eg selegiline);
severe disorders in the metabolism due to other diseases (diabetes mellitus).
This medicine should not be taken by children under 18 years of age, pregnant women and nursing mothers.
Take special care with Taliton tablets. The use of this medicine needs attention in some cases, so please tell your doctor if:
Although high blood nolyagne been treated, its values often change or high blood pressure is due to some other known disease (e.g. tumor-forming hormones, thyroid disease, renal artery narrowing);
if you open conduction disorder of the heart (right bundle branch block) of elektrokordnograma;
you feel a drop but blood pressure and feel dizzy when you stand up;
Property inflammatory disease of the heart (cordite), a serious breach in the peripheral blood flow and heart valve disorders (disorders in the way but the ejection of blood);
currently taking alpha 1 blocker (eg prazoznn, gerazozin) or alpha-2 aktivotor (eg metnldopo, guonfatsin).
This medicinal product should be used with caution in these cases, please tell your doctor:
for all past and present diseases (emphysema, shortness of breath, Dabei diabetes, psoriasis);
present for cardiovascular disease (eg, angina Prinzmetal type), kidney disease or current thyroid;
if you are allergic to any medicine or something, vklyuchigelno to uhapvannya of insects.
If you suffer from heart failure, taking high doses of diuretics (water tablets), if you are over age 70 or if your blood pressure is low, then there is a risk to get a sudden drop in blood pressure, dizziness or fainting upon receipt of the first dose or upon receipt of a first dose increased due to vasodilatory effects of the drug.
The risk of these side effects may be reduced if treatment begins with small doses
be under medical supervision, and if these tablets be taken during meals but.
Tell your doctor if your symptoms associated with existing heart failure worse (difficulty breathing, swelling of the feet).
If you are prescribed Taliton due to heart failure and upper gronitsa blood pressure below 100 mm Hg, imate coronary artery disease, a narrowing of the blood vessels and / or renal impairment, treatment with this drug may lead to worsening of renal function.
Tell your doctor if you notice any acknowledged worsening of renal function (increase your weight in a short time, reduced urine output).
This product can to lower the heart rate, which is normal, but consult your doctor if you feel unwell or if heart often gets less than 55 beats per minute.
Tell your doctor if you have coronary artery disease and if
clamping chest pain occurs more often, not only as a result of inducing the usual
January factors or if it lasts longer and is not affected by the usual treatment.
Taking other medicines
May occur to drugs vzaimzodeystviya with drugs that are taken recently, are currently taking or will take in the future, Please tell your doctor or formatsevt if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
From very important that you tell your doctor if you are taking verapamil, diltiazem, nifedipine or clonidine, on the occasion of arrhythmia (irregular heartbeat), high blood pressure or angina and whether you are taking digoxin and diuretics in relation to heart failure, or taking NSAIDs (indomethacin, ibplrofen) as painkillers.
Besides the above mentioned drugs, concomitant use of these drugs and Taliton requires caution:
Rifamitsnn, barbiturates, beta-agonists (terbutaline, salbutamol, fenoterol, solmaterol), aminophylline, theophylline, ergotamine, cimetidine, cyclosporine, quinidine, fluoxetine, propofenon, medicines for high blood pressure, drugs lowering blood poured effect, hypnotics, sedatives, antidepressants and drugs for general anesthesia.
Regular use but alcoholic beverages during treatment may intensify as the effect of the drug and the effects but alcohol.
The drug may enhance the effects of insulin and other hypoglycemics.
If you are taking medicine containing clonidine concomitantly with Taliton not stop taking any of them, not to talk to your doctor.
If you are in treatment for a severe allergy, if you accept the hospital if you have surgery, tell your doctor (especially physician and anesteeziologa) that you are on treatment
Taliton with as soon as possible.
If you take Taliton not stop treatment abruptly. Tovo should be gradual and it has to strictly follow the instructions of the physician.
Pregnancy and lactation
Its use is contraindicated in pregnancy.
Because many drugs are excreted in human milk, and beta-bpokerite able to have severe effects
on the infant, treatment with korvedilol need to be stopped if breast-feeding.
If treatment with Taliton absolutely necessary, you should stop breast-feeding.
If you are pregnant or breast-feeding, ask your doctor or pharmacist before taking any medicine.
Driving and using machines
The drug can affect reaction time, which can cause problems in carrying out activities with an increased risk. At the beginning of treatment and dose increase the risk of a sudden drop in blood nolyagane, dizziness and fainting, so should not drive or operate machinery during these periods.

Important information about some ingredients of the tablets Taliton
Each tablet contains 50mg of lactose. This is the amount that must be taken into account in the lactase deficiency (lack of enzyme, which breaks down milk sugar) or other rare diseases of metabolism (e.g. galakgozemiya and / or glucose-galactose malabsorption syndrome).
Each tablet contains 12,5 mg of sugar. This quantity may be important in diabetes or in some rare hereditary diseases such as hereditary fructose intolerance, glucose-galactose malabsorption or zaharazo-izomaltazna failure.
This medicine may cause a reduction of slaznato secretion, which can become a problem if you wear contact lenses.

3. HOW TO TAKE TALITON TABLETS
Always take Taliton tablets exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Chronic heart failure;
The recommended initial daily dose is 6,25 mg during the first 14 days (1/2 6,25 mg tablet morning and evening). If necessary, your physician may increase the dose every 2 weeks up to 12,5 mg per day (1 tablet of 6,25 mg morning and evening), then to 25 mg per day (1 tablet of 12,5 mg in the morning and evening) and up to 50 mg daily (1 tablet of 25 mg) in the morning and evening.
If your weight is up to 85 kg. the maximum recommended dose is 50 mg per day (1 tablet of 25 mg in the morning and evening), and if it is over 85 kg., the maximum dose is 100 mg daily (2 tablets of 25 mg in the morning and 2 tablets of 25 mg in the evening ).
Esentsiayana hypertension: The recommended initial daily dose is 12,5 mg during the first two days (1 tablet of 12,5 mg once daily in the morning or 1 tablet of 6,25 mg in the morning and evening).
The recommended maintenance dose is 25 mg per day (one 25 mg tablet once daily in the morning or 1 tablet of 12,5 mg in the morning and evening). If necessary, at the earliest after 14 days of treatment, your doctor may increase the dose to ea maximum of 50 mg daily (about 1 25 mg tablet morning and evening).
Chronic stable angina (coronary artery disease): The recommended initial daily dose is 25 mg in the first two days (1 tobpetka of 12,5 mg in the morning and evening).
The recommended maintenance dose is 50 mg per day (1 tablet of 25 mg in the morning m evening).
If necessary, at the earliest after 14 days of treatment, your doctor may increase the dose to a maximum of 100 mg per day (two 25 mg tablets morning and 2 tablets of 25 mg in the evening).
The tablets should be taken with plenty of fluids before or after meals, which
You more comfortable. If you suffer from heart failure, it is recommended to take the tablets with meals to avoid the risk of a sudden drop in blood pressure.
The effect of the drug in terms of lowering blood pressure develops quickly and lasts for 24 hours, and the maximum benefit can be expected 2-3 hours after its adoption.
In the long term maximum effect develops after 3-4 weeks of treatment.
The elderly, those with heart failure and renal impairment
can receive the usual adult dose. In elderly patients with angina maximum daily dose is 50 mg (1 tablet 25 mg in the morning and evening).
If you have impaired liver function should not take these tablets. Then
it is necessary to consult with your doctor.
Do not stop taking Taliton suddenly as it may to cause worsening of your condition, triggering the appearance of firming chest pain and high blood pressure, especially in the case of coronary artery disease, so treatment should be withdrawn gradually and only if recommended by your doctor.
If you take more than the required dose Toliton, seek medical help immediately.
Heavy predozirone can lead to strong sweetness of blood pressure and heart frequent, heart failure, shortness of breath, vomiting. Without immediate medical attention may occur fainting, seizures, collapse and cardiac arrest.
It may need even hospital intensive care.
If you forget to take Toliton at the usual time, take it as soon as possible. If it's time for the next intake not take a double dose to make up for a missed dose. Do not risk overdose, never take two doses at the same time.



4. POSSIBLE SIDE EFFECTS
Like all medicines, Taliton can cause side effects, although not everybody gets them.
Aka appear any of the following stop taking Taliton and tell your doctor immediately or go to the nearest emergency unit zo:
Swelling of the arms, legs, lips, mouth or throat and difficulty swallowing, shortness of breath IME
Seizure
These complaints are a sign of an allergic reaction or a severe drop in blood pressure. In either case you need medical attention or hospitalization. These side effects are severe, but occur in very rare cases.
• Skin rash can also be a sign of allergic reaction. Stop taking the drug immediately and consult your doctor. To avoid the risk of more serious complaints, seek medical help immediately if the rash is strong and covers the entire body.
Inform your doctor if you notice the following:
Common (> 1%) adverse events occurring at any dose, and high blood pressure and angina. Headache, fatigue, a sudden drop in blood pressure when standing, low blood pressure, asthma (shortness of breath), pain in extremity, reduced tear secretion, nausea, diarrhea, abdominal pain, skin reactions, itching.
Common (> 1%) adverse reactions occurring regardless of dose angina Loss but consciousness firming chest pain.
Common (> 1%) adverse reactions occurring at high doses: Dizziness, low heart rate.
Uncommon (<1%) adverse reactions occurring in frequent doses: Visual disturbances.
Other uncommon (0.1-1%) side effects Depressed mood, sleep disturbances, tingling, peripheral vascular disorders, cold extremities, swelling of the limbs, disturbance in atrioventricular conduction, aggravation of existing heart failure, nasal mucosa, constipation, vomiting, impotence.
Other rare (<0.1%) side effects: abnormal liver function tests, reduced number of white blood cells and platelets, dry mouth, difficulty in urinating, flu-like symptoms.
Adverse reactions nablyudavanipri patients with heart failure:
Very frequent (> 10%) adverse events occurring at any dose: swelling of the feet, diarrhea, a significant increase in the blood sugar level in diabetic patients.
Common (> 1%) adverse reactions occurring independent of dose: Low blood pressure, a sudden drop in blood pressure when standing up, worsening of heart failure, loss of consciousness, atrial-ventricular conduction disorder, nausea, vomiting, impaired renal function ( especially in offense peripheral circulation) renal impairment.
Very common (> 10%) adverse reactions occurring at high doses: Dizziness
Common (> 1%) adverse reactions occurring at high doses: Reduced heart rate, visual disturbances.
Of the above side effects sudden drop in blood pressure upon standing,
dizziness, tiredness, nausea, abdominal pain, diarrhea, decreased heart rate and low blood pressure occur most commonly at the beginning of treatment and are usually mild and transient.
However, you continue for longer or if you are concerned, please consult your doctor.
Immediately contact your doctor if constricting chest pain, shortness of breath or loss of consciousness.
You may not experience any of the above side effects.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE TALITON TABLETS
Keep out of reach of children.
Do not store above 25 ° C. Protect from light / moisture.
Do not use Taliton tablets after the expiry date stated on the packaging. The term of
date refers to the last day of that month.