Terazosin 2 mg.

WHAT terazosin ACCORD AND WHAT IT IS USED
Terazosin belongs to the group of drugs known as alpha-1-selective adrenoceptor blocking agent.

Terazosin Accord is used for:
treatment of mild to moderate high blood pressure (hypertension);
treatment of a condition called benign prostatic hypertrophy (growth) of the prostate (BPH). This condition is caused by too rapid growth of the prostate gland and is common for older men. When the prostate gland becomes too large, it can partially block the leakage of urine from the bladder. This leads to symptoms such as:
weak or interrupted flow of urine;
need to pass urine, or more often during the night;
sudden need to pass urine.

2. BEFORE YOU TAKE terazosin ACCORD
Do not take Terazoznn Accord:
If you are allergic (hypersensitive) to the active substance terazosin (eg. Prazosin, doksazin, alfuzosin, tamsulosin and indoramin) and excipients;
If you've ever endured a brief loss of consciousness, while urine or just after you pass urine. This symptom occurs more often if you get at night to separate urine.
Take special care with terazosin Accord
Please tell your doctor if you have or have ever suffered from any of the following conditions or diseases.
Fainting, dizziness or instability (feeling that everything revolves around) caused by low blood pressure when standing. To e more prevalent:
when starting treatment for the first time;
when retreated after a few days break;
if your body does not have enough fluids;
if you are on a diet low in salt;
in older people (over 65 years).
      More likely to experience fainting when standing if:
terazosin your dose is increased dramatically;
you are taking a diuretic (a medicine for more urine) or another medicine that helps to reduce your blood pressure. You may notice that you have a rapid heart beat just before you pass out. The risk of fainting is greatest between 30 and 90 minutes after you take your dose of terazosin.
Hypotension (low blood pressure). Your doctor will monitor your blood pressure;
Heart problems such as water in the lungs or heart failure;
Impaired liver function;
Advanced liver failure, which requires dialysis or intensive care;
Lack of urination or decrease in urine output;
Obstruction of the upper urinary tract (where it is difficult for urine to flow from the kidneys to the bladder);
Persistent urinary tract infection (infection that is not affected by the treatment applied);
Bladder stones.
If you are eye surgery because of cataracts (lens opacities), please contact your eye before surgery specialist that use or are explorers terazosin. This is due to the fact that terazosin may cause complications during surgery, which can be overcome if the specialist is prepared in advance.

Taking other medicines
If taking more than one drug, there is always a risk of drugs to interfere with one another. Therefore, please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

It is especially important for your doctor to know if you are taking:
Some patients who take alpha-blockers to treat high blood pressure or prostate enlargement may experience dizziness or lightheadedness, that may be caused by low blood pressure upon sitting or standing up quickly. Some patients can experience these symptoms when taking medication for erectile dysfunction (impotence) concomitantly with alpha-blockers. To reduce the likelihood of these symptoms appear, you should take regular daily dose of your alpha-blocker before you start taking this medicine for erectile dysfunction;
Clonidine (administered intravenously);
Nitrate used to treat heart pain (angina);
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac, used as anti-rheumatic drugs or painkillers;
Estrogens (female hormones, eg. Used in contraceptives);
Drugs, including some of the following: dopamine, ephedrine, epinephrine, metaraminol, methoxamine, phenylephrine;
Sympathomimetic drugs (eg. Drugs that elevate blood pressure or heart rate or expanding the trachea as epinephrine used in the treatment of severe allergic reactions and beta-2 antagonists useful in the treatment of asthma);
Drugs used for the treatment of erectile dysfunction (PDE-5 inhibitors, e. Sildenafil, tadalafil, vardenafil).
 
Taking terazosin Accord with food and drink
Intake of food and drink will impact your treatment with terazosin Accord. Please be aware that alcohol can increase your risk of dizziness, lightheadedness, or drowsiness.

Pregnancy and lactation
Terazosin Accord is not recommended during pregnancy and lactation.
Ask your doctor or pharmacist before taking any medicine.

Driving and using machines
Terazosin Accord may have a significant impact on the ability to drive and use machines.
May appear vertigo, dizziness or drowsiness the initial dose or in connection with missed doses and subsequent re-initiation of therapy with terazosin. Patients should be cautioned about these possible adverse events and circumstances that may occur and advised to avoid driving or hazardous tasks about the first 12 hours after the initial dose or when the dose is increased.

Important information about some of the ingredients of terazosin Accord
This product contains milk sugar (lactose). If you know that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. HOW TO TAKE terazosin ACCORD
Always take terazosin Accord exactly as you have been told by your doctor. If you are not sure, ask your doctor or pharmacist.
Tablets should be taken once daily at bedtime, as there is always the risk of dizziness or fatigue.
Avoid sudden changes in position or activities that may cause dizziness or drowsiness. This is especially important if you are elderly (over 65 years) and / or when treatment has commenced.

Treat high blood pressure (hypertension)
Your doctor will adjust your dose depending on how you respond to treatment.
The usual dosage is shown below:
Treatment of hypertension:
First week of treatment - recommended dose terazosin Accord 1 mg daily;
Second week of treatment - recommended dose terazosin Accord 2 mg daily;
Usual maintenance dose (if blood pressure is well controlled) - 2 mg daily;
If blood pressure is not controlled at a dose of 2 mg per daily dose may be doubled weekly intervals. Do not take more than the maximum dose listed below.
Maximum dose - 20 mg daily.
 
Your doctor will increase your dose terazosin while your blood pressure is not well controlled.
Once your blood pressure is well controlled. Your dose will not change. The usual maintenance dose is 2 mg per day, although it is sometimes necessary to use more dose. Do not take more than the maximum dose of 20 mg.
Treatment of hypertension with terazosin is usually long. You should not stop treatment unless your doctor tells you. If you need to cancel your treatment with terazosin for a short time, you have to restart treatment with the initial dose.
If your doctor prescribes another medicine for blood pressure in addition to terazosin, it will reduce the dose of terazosin.

Treatment of benign prostatic hypertrophy (increase) of the prostate (BPH):
Your doctor will adjust your dose depending on your response.
The usual dosage is shown below:
First seven treatment - recommended dose Terazoznn Accord 1 mg daily;
Second and third week of treatment - recommended dose Terazoznn Accord: 2 mg daily;
The fourth week of treatment, the response to treatment was analyzed and if needed, the dose is increased - the recommended dose Terazoznn Accord: to 5 mg per day;
Usual recommended dose - 5 mg once daily;
Maximum daily dose - 10 mg daily.

You may suffer from short-term side effects (see Section 4 Possible side effects) whenever your dose is increased. If any of these side effects continue to manifest, your doctor may reduce your dose.
After 4 weeks of maintenance dose, your doctor will assess how well you respond to treatment.

Children and adolescents under the age of 18
Terazosin is not recommended for adolescents aged 18 years.

Elderly
It is not necessary to adjust the dose in elderly patients (over 65 years).
You should take your tablets at the same time each day, ie before bedtime. Swallow your tablets with half a glass of water. Do not crush or crush them.

If you take more than the amount of terazosin Accord
If you take more than the amount of terazosin Accord or if someone else take terazosin Accord, contact for advice Accident and Emergency department of your nearest hospital. Take with you all the other tablets or empty box for easy identification. Taking too many tablets can lead to a sharp decrease in your blood pressure and other serious effects occur.

Possible overdose symptoms are:
dizziness, vertigo;
confusion;
fainting;
shortness of breath;
hypotension (low blood pressure);
palpitations (feel your heart beats in your chest);
rapid heartbeat;
nausea;
low levels of glucose (sugar) in the blood;
low levels of potassium in the blood;
muscle spasms (seizures);
If you forget to take terazosin Accord:
If you forget to take the tablets terazosin Accord, you can pick them up as soon as you remember unless it is time for your next dose. In this case you should continue with your medication as prescribed. Do not take a double dose to make up for a missed dose. Do not take more than one tablet per day.

If you stop taking terazosin Accord:
Do not stop taking terazosin Accord unless your doctor tells you.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, terazosin Accord can cause side effects, although not everybody gets them.
The following side effects are important and will require immediate action if you get them. You should stop taking terazosin Accord and meet with your doctor immediately if you experience the following symptoms:
Rare side effects which affect less than 1 in 1,000 patients:
Prolonged and painful erection.
Very rare side effects which affect less than 1 in 10,000 patients:
Sudden allergic reaction with shortness of breath, hives, wheezing and a fall in blood pressure.
The following adverse reactions have also been reported:
Very common side effects (less than 1 in 10, but at least 1 in 100 patients):
nervousness;
Blurred or altered vision;
shortness of breath;
Back pain;
Erectile dysfunction;
drowsiness;
Tingling sensation on the skin;
Feeling that everything revolves around (dizziness);
palpitations;
Chest pain;
Sense of weakness;
dizziness;
constipation;
diarrhea;
vomiting;
dizziness;
headache;
Pain in extremity;
nausea;
itching;
Skin rash;
Nasal congestion;
sinusitis;
Nosebleeds (epistaxis);
Fluid retention and swelling;
Fainting upon standing.
Common side effects (less than 1 in 100, but at least 1 in 1,000 patients):
depression;
Hives;
Decreased sexual desire;
Loss of consciousness;
Gain.
Rare side effects (less than 1 in 1,000, but at least 1 in 10,000 patients):
Urinary tract infection and urinary incontinence (mainly reported in women in menopause).
Very common side effects (less than 1 in 10,000 patients):
Easy bruising or bleeding;
Irregular heart rhythm (atrial fibrillation).
In addition, the following adverse reactions were reported in clinical trials or in marketing experience (not necessarily adverse reactions caused by terazosin): fever; back pain, shoulder or abdomen; flushing; dry mouth; indigestion; flatulence; pain in joints or muscles; anxiety; bronchitis; symptoms of fever and flu; sore throat; cough; conjunctivitis; tinnitus and frequent urination.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE terazosin ACCORD
Keep out of the reach and sight of children.
Store in the original package to protect from light.
Do not use terazosin Accord after the expiry date stated on the carton and blister. The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.