Tinidazol 500 mg. 4 tablets

WHAT tinidazol AND WHAT IT IS USED?

Tinidazol is an imidazole derivative. The product is active in terms of protozoa and anaerobic bacteria. These groups include Trichomonas, entameba and Lamb.

The product penetrates into the microbial cell and destroys the helical structure of DNA or inhibit its synthesis.

Tinidazol apply to:

Treatment of infections caused by susceptible microorganisms as the product:

• Anaerobic infections:

- Intra-abdominal (tummy) - peritonitis, abscesses; -gynecological - Endometritis, endometriosis, Tubo-ovarian abscess; -Postoperativni Wound infections;

- Bacterial septicemia, when clinically indicated after administration of parenteral therapy if the patient's condition allows to oral switch;
- Infections of the skin and soft tissues;

- Infections of the lower respiratory tract - pneumonia, empyema, lung abscess;

• Non-specific vaginitis;

• acute ulcerative gingivitis (gingivitis with ulceration);

• Urogenital trichomoniasis in men and women;

• giardiasis;

• Intestinal amoebiasis;

• amoebic infection of the liver.

Prevention of postoperative infections caused by anaerobic bacteria, particularly in surgery of the colon, for gastrointestinal and gynecological surgery.

2. WHAT YOU NEED TO KNOW BEFORE starting treatment with tinidazole Actavis?

Tinidazol does not apply to:

• Hypersensitivity to the active or excipients.

In this medicinal product, please note the following:

The product is applied with caution in organic neurological disorders and blood dyscrasias.

Products with similar chemical structure as tinidazole can lead to onset of neurological manifestations such as confusion, dizziness, incoordination and ataxia. In such events, treatment should be discontinued. In trichomoniasis treatment is carried out simultaneously for both partners.

Application of tinidazol with food and drink

During treatment should avoid alcohol because of the risk of

occurrence of t. pomegranate. disulfiram - like reaction - colic, vomiting, rapid heartbeat and flushing. Alcohol should be avoided for 72 hours after discontinuation of the product.

Pregnancy

Before intake of any medicine, consult your doctor or pharmacist. Do not use during pregnancy.

Breastfeeding

Before intake of any medicine, consult your doctor or pharmacist

Tinidazol not be used during breastfeeding. The product passes into breast milk and there is a concentration as in the blood.

Driving and using machines

Patients should be informed that in rare cases may occur neurological symptoms such as confusion, incoordination and ataxia and this will affect the ability to drive and use machines.

Taking other medicines

Please tell your doctor shi shi pharmacist if you have recently taken recently other medicines, even if they are not prescribed by your doctor

Tinidazole Actavis enhances the action of coumarin anticoagulants (products that inhibit blood clotting), which requires dose adjustment of anticoagulants during its intake and 8 days after discontinuation of treatment.

3. HOW TO USE tinidazol?

Always take tinidazole Actavis exactly as your doctor! The tablets are taken orally during or after meals. Anaerobic infections

Adults - starting dose of 2g (four tablets) on the first day; subsequent days - a day lg adopted one or two doses of 500 mg for 5-6 days. The duration of treatment over seven days was determined after observation of clinical status and laboratory findings. Children under 12 years - no clinical data.

Nonspecific vaginitis

Adults - a single oral dose of 2g. When a persistent infection can be applied 2g in two consecutive days (total dose 4g).

Acute ulcerative gingivitis

Adults - single oral dose of 2g.

ATM

Adults - single oral dose of 2g. Children - a single oral dose of 50 to 75 mg / kg. If necessary, can be repeated.

Giardiasis

Adults - single oral dose of 2g.

Children - a single oral dose of 50 to 75 mg / kg. The dose can be repeated.

Intestinal amoebiasis

Adults - a single oral dose of 2g for 2-3 days.

Children - a single oral dose of 50 to 60 mg / kg daily for three consecutive days.

Amoebic infection of the liver

Adults - total dose ranging from 4.5 to 12g, depending on the virulence of the agent Entamoeba histolytica.

The starting dose is 1.5 to 2g once a day for three days. If this scheme ineffective, treatment can last up to six days.

Children - a single oral dose of 50 to 60 mg / kg daily for five days.

Prophylaxis of postoperative infections

Adults - single dose of 2g approximately 12 hours prior to intervention. Children under 12 years - no clinical data.

Elderly

There are no specific recommendations regarding dosage.

If you have the impression that the effect of the application of tinidazole Actavis is too strong or too weak, talk to your doctor or pharmacist!

If you take a large amount of the drug:

When taking a higher dose than prescribed immediately consult a doctor!

Signs - agitation, headache, fast heartbeat; in severe cases - shock, low blood pressure, shortness of breath.

Treatment - gastric emptying. Symptomatic treatment, no specific antidote. The product is hemodialysis.

If you forget to tinidazol

If you forget to take another dose, take it missed as soon as possible, but do not double the next one.

4. POSSIBLE SIDE EFFECTS

Like any other medicine, tinidazol can cause side effects

Side effects are rare, mild and usually disappear quickly. Can be observed:

• Gastrointestinal effects - nausea, vomiting, anorexia, diarrhea, metallic taste in the mouth, abdominal pain;
• Hypersensitivity reactions - skin rashes, itching in the genital organs, urticaria, rarely life-threatening reactions;
• Neurological effects - confusion, incoordination, ataxia (movement disorders);
• Reactions of blood - low white blood cell count;
• Other - headache, tiredness, bumps on the tongue, dark urine.

If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

5. Storage

At temperatures below 25 ° C.
Keep out of reach of children!
Do not use after the expiry date stated on the package!
Shelf life: 3 (three) years