TOPILEKS table. 50 mg

TOPILEKS WHAT IS AND WHAT IT IS USED FOR?

Topileks is a medicine for the treatment of epilepsy.

Topileks used to treat epilepsy patients seizures begin in a limited area of the brain and / or clinical generalized tonic seizures.

Can be used alone or as an adjunct to treatment with other antiepileptic drugs.

Topileks is also used to prevent frequent attacks of migraine headaches in adults in cases where there is no effect of previous treatment with other medicines.

BEFORE YOU TAKE TOPILEKS

Do not use Topileks:

 If you are allergic to topiramate or any of the other ingredients of Topileks

 Prevention of migraine if you are pregnant or you are a woman of childbearing potential and not using an effective contraceptive method.

Take special care with Topileks

If you suffer from kidney or liver disease. Ask for advice from your doctor before starting treatment

 Stays in warm temperature environments do exercise or physical work. In that case, take enough fluid to reduce the effect of side effects associated with high ambient temperature. This is especially true for children, since it is possible to reduce perspiration during treatment with topiramate.

 In case you have had kidney stones. In that case, take more fluids. You should avoid taking medicines that may cause the formation of kidney stones or greasy foods low in carbohydrates, as this may increase the risk of forming kidney stones.

If you get a sudden myopia and / or eye pain should immediately contact your doctor. In many patients, this medicine can cause a sudden onset of glaucoma.

 If you notice any changes in mood, feeling depressed or have thoughts of harming yourself, you should immediately contact a doctor

 If you use medicine to prevent migraine control your weight. If you notice a significant and lasting weight loss, please share with your doctor. You may need treatment discontinuation.

This medicine can reduce bicarbonate levels in your blood and cause excessive acidity of the blood. This is especially true if you suffer from other diseases that makes you sensitive to low levels of bicarbonate in implementing diets containing fat and protein, or taking other medicines. Usually bicarbonate concentrations decreased at the beginning of treatment. Your doctor may ask you to take a blood sample to monitor the concentration of bicarbonate in the blood.

There is only limited information on the use of this medicine in children under 12 years.

Small number of people, epileptics such as toparamat have had thoughts of harming or killing yourself. If you have these, contact your doctor.

Pregnancy and lactation

Ask for advice from your doctor before taking any medicine.

This medicine may harm your unborn child, but the other untreated severe epilepsy and seizures due to abrupt discontinuation of the drug may lead to more damage.

Your doctor will decide whether to continue, change or stop taking.

Your doctor may advise you to discontinue breastfeeding since topiramate is excreted in breast milk.

Important information about some of the ingredients of Topileks

Topileks contains lactose. If you are told by your doctor that you have intolerance to some sugars, consult your doctor before starting treatment.

Topileks contains sunset yellow, which may cause allergic reactions.

HOW TO TAKE TOPILEKS

The doctor prescribed a dose that is specific to you. Usually, treatment is started at low dose and gradually increasing to reduce the risk of side effects.

If you have kidney or liver disease, your doctor may prescribe a lower dose and for a longer time to adjust the dose.

There are other strengths of the product, if it can not achieve the required dosage of this medicine.

Self-treatment of epilepsy with Topileks

Adults and adolescents over 12 years

Treatment is usually started with a dose of 25 mg, taken once in the evening for one week. Then the total daily dose is increased every week or two weeks with 25 or 50 mg daily. in case you notice any side effects, your doctor may increase the dose more slowly than usual or more than the above intervals. The usual maintenance dose is 100 mg daily in two divided doses. In self using this product for epilepsy, the maximum daily dose is 400 mg.

Use in combination with other antiepileptic drugs

Adults and adolescents over 12 years

Treatment is usually started with a dose of 25-50 mg taken every night for one week. Then the total daily dose is increased every week or two weeks with 25 or 50 mg daily. The usual dose is 200 to 400 mg in two divided doses. In some patients achieve better control of the disease with a single dose. Some patients may require a maximum daily dose of 800 mg, which is the maximum dose and should not be exceeded.

When switching from treatment with other antiepileptic drugs in monotherapy with Topileks a gradual dose reduction of other antiepileptic medication with a third week. In some cases, based on medical advice and possible dose Topileks be reduced.

Prophylaxis of migraine in adults

Your doctor will start with a dose of 25 mg taken in the evening and then increase it to the lowest level necessary to prevent repeated migraine attacks. The usual maintenance dose is 50 mg taken twice a day, but your doctor may advise you to use a lower dose.

Consult your doctor or pharmacist if you feel that the effect of Topileks is too strong or weak.

Route of administration

The active substance topiramate has a bitter taste. Therefore, the tablets should not be divided or crushed.

Take the tablets, regardless of food intake, with sufficient fluid.

POSSIBLE SIDE EFFECTS

Very common - fatigue, dizziness, drowsiness, nervousness, headache, nausea, weight loss, memory problems, loss of appetite, confusion, delayed thought processes, depression, difficulty in concentration, restlessness, problems with coordination, blurred vision, visual disturbances , speech disorders

Common - anemia, nosebleeds, red or purple spots on the skin, decreased white blood cells or platelets, a sense of indifference, frustration, euphoria, anxiety, anxious thoughts, decreased sexual interest, aggressive reactions, constipation, abdominal pain, alopecia, menstrual disorders, impotence, pain in the body and bones, insomnia.

Uncommon - delusional personality disorders, suicidal thoughts, slow movements, slow thinking and feeling, shortness of breath, diarrhea, vomiting and dry mouth, itching, inflammation of hair follicles.

Rare - elevated liver enzymes, acute myopia from glaucoma, eye pain, decreased neutrophil white blood cells.