TORAZIDEKS table. 10 mg

INDICATIONS:

Edema in patients with heart failure

Dosage and use:

Adults:

The usual dose is 5 mg orally once daily. This is typically the maintenance dose. The dose may be increased gradually to 20 mg once daily.

Elderly:

There are different dosage recommendations for the elderly. Data from comparative studies between older and younger patients, however, are insufficient.

Children:

There is no experience in children torasemid.

Hepatic and renal impairment:

Information on dose adjustment in patients with hepatic or renal insufficiency is limited. Should be treated with caution because plasma concentrations may be higher.

Method of application:

Oral prolozhenie.

Tablets should be swallowed and not chewed with a little liquid. Torasemid applied usually as long-term treatment or disappearance of swelling.

CONTRAINDICATIONS:

Hypersensitivity to torasemid, sulfonylurea medicines or any of the excipients;

Renal failure with anuria;

Hepatic coma and coma;

Hypotension;

Breastfeeding

PREGNANCY and BREAST-FEEDING:

No evidence of human experience on torasemid effect on the embryo and fetus.

While studies in rats revealed no teratogenic effects in pregnant rabbits and rats, fetal and maternal toxicity after administration of high doses. torasemid passes in the fetus and cause electrolyte imbalance. There is also the risk of neonatal thrombocytopenia.

No information on excretion in breast milk torasemid in humans and animals. Therefore, prescribing torasemid during lactation is not recommended.

To raise additional experience torasemid should be used during pregnancy only after careful consideration of whether the benefits clearly outweigh the risks. You should use the lowest possible dose.

SIDE EFFECTS:

Metabolism and nutrition

Common - worsening metabolic alkalosis, muscle cramps, increased concentration of uric acid and blood sugar and lipid levels, hypokalaemia with concomitant diet with low intake of potassium from vomiting, diarrhea after excessive use of laxatives, and in patients with hranichna liver dysfunction.

Depending on the dose and duration of treatment may be disturbed by the water and eletrolitniya balance, particularly as. hypovolemia, hypokalemia and / or hyponatremia.

Cardiovascular disorders:

Very rare - confusion, hypotension, and disturbances of the heart and peripheral circulation.

Gastrointestinal Disorders

Common - gastrointestinal disorders / anorexia, beams in the stomach, nausea, vomiting, diarrhea, constipation /, especially in early treatment

Very rare - pancreatitis

Renal and urinary disorders

Uncommon - increased concentrations of creatinine and blood urea nitrogen. In patients with micturition disturbances, increased urine flow can lead to urinary retention and bladder hyperextension.

Hepatobiliary disorders

Common - increased blood levels of some liver enzymes

Skin and subcutaneous tissue disorders

Very rare - allergic reactions, severe skin reactions

Blood and lymphatic system

Very rare - reducing the number of platelets, red blood cells and / or leukocytes

General disorders

Common - headache, dizziness, fatigue, asthenia

Uncommon - dry mouth, paresthesia

Very rare - dizopiya, tinnitus, loss of hearing.