VIGRANDE 100 mg. 1 tablet

WHAT VIGRANDE IS AND WHAT IT IS USED
VIGRANDE belongs to a group of medicines called inhibitors of phosphodiesterase type 5. It works by helping to relax the blood vessels in the penis, allowing blood to flow during sexual arousal. VIGRANDE will only help you to get an erection if you are sexually stimulated. You should not take VIGRANDE if you do not have erectile dysfunction. You should not take VIAGRANDE if you are a woman.
VIGRANDE is for the treatment of erectile dysfunction mazhes, sometimes referred to as impotence. It means that man can not get, or keep a hard, erect penis suitable for sexual activity.

2. BEFORE YOU TAKE VIGRA Do not take VIGRANDE
- If you are taking medicines called nitrates, as the combination may cause a potentially dangerous decrease in your blood pressure. Tell your doctor if you are taking any of these medicines which are often given for relief of angina pectoris (or "chest pain"). If you're not sure, ask your doctor or pharmacist.
- If you use one of the drugs known as nitric oxide donors such as amyl nitrite ("poppers"), as the combination may also lead to a potentially dangerous decrease in your blood pressure.
- If you are allergic (hypersensitive) to sildenafil or any of the other ingredients of VIGRANDE.
- If you have severe heart or liver problem.
- If you have recently had a stroke or heart attack, or if you have low blood pressure.
- If you have certain rare inherited eye diseases (such as drinking-tozen retinitis).
- If you have ever had loss of vision due to non-arteritic anterior ischemic optic neuropathy (NAION).

Take special care with VIGRANDE
Tell your doctor
- If you have sickle cell anemia (an abnormality of red blood cells), leukemia (cancer of blood cells), Mul myeloma (bone marrow cancer).
- If you have a deformity of the penis or disease Peyronie.
- If you have heart problems. In this case, your doctor should carefully check whether your heart can take the additional strain of having sex.
- If you currently have a stomach ulcer or problems with blood clotting (such as haemophilia) '.
- If you experience sudden decrease or loss of vision, stop taking VIGRANDE and immediately contact your doctor.
VIGRANDE should not be used in conjunction with other types of drugs for oral or topical treatment of erectile dysfunction.

Special considerations for children and adolescents
VIGRANDE should not be given to individuals under the age of 18.
Special considerations for patients with kidney or liver problems You should tell your doctor if you have kidney or liver problematic th. Your doctor may decide to prescribe a lower dose.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Sildenafil (the active substance of the product VIGRANDE) can be reacted with certain drugs, particularly those used to treat chest pain. In case of emergency, you should tell any health professional. which treat you now that you have taken VIGRANDE and when you did. Not priemayteVIGRANDE with other medicines unless your doctor tells you that you can.
You should not take VIGRANDE if you are taking medicines called nitrates as the combination of these products may cause a potentially dangerous decrease in your blood pressure. Always tell your doctor or pharmacist if you are taking any of these medicines which are often given for relief of angina pectoris (or "chest pain").
You should not take VIGRANDE if you are using any of the drugs known as nitric oxide donors such as amyl nitrite ("poppers"), as the combination may also lead to a potentially dangerous decrease in your blood pressure. If you are taking medicines known as protease inhibitors, such as for the treatment of HIV, your doctor probably will prescribe a start at the lowest dose (25 mg) of VIGRANDE.
Some patients who are treated with alpha blocker to treat high blood pressure or prostate enlargement may experience dizziness or light-headedness, which may be caused by low blood pressure upon sitting or standing up quickly. Some patients have experienced these symptoms when taking sildenafil with alpha-blockers. This is most likely to occur within 4 hours after taking sildenafil. You must be a regular daily dose of your alpha-blocker before taking VIAGRA, to reduce the likelihood of these symptoms. Your doctor may start you on a lower dose (25 mg) of VIAGRA.

Taking VIGRANDE with food and drink
 VIGRANDEcan be taken with or without food. However, you may notice that VIGRANDE begins to act more slowly if you take it with a heavy meal.
Drinking alcohol can temporarily impair your ability to get an erection. To get the maximum benefit from your medication, you are advised not to drink excessive amounts of alcohol before taking VIGRANDE

Pregnancy and lactation
VIGRANDE is not indicated for use in women.

Driving and using machines
Sildenafil (the active ingredient of the product VIGRANDE) can cause dizziness and can affect vision. You need to know how you react to VIGRANDE before you drive or operate machinery.

Important information about some of the ingredients of VIGRANDE
No special precautions applicable to the other ingredients of this medicine produkt.3. HOW TO TAKE VIGRANDE
Always take VIGRANDE exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist. The usual initial dose is 50 mg (amount of active substance in the tablet 1 from the product VIGRANDE 50 mg).
You should not take VIGRANDEmore than once a day.
VIGRANDE should be taken about one hour before you plan to have sex. Swallow the tablet whole with a glass of water.
If you feel that the effect of VIGRANDE is too strong or too weak, talk to your doctor or pharmacist.
VIGRANDE will only help you to get an erection during sexual stimulation. Time that appears the effect of VIGRANDE is different in individuals, but usually is between half and one hour. If you take VIGRANDE during a heavy meal, the effect may occur more slowly.
If VIAGRA does not help you to get an erection or if your erection does not last long enough to complete sexual intercourse you should tell your doctor.

If you take more dose of VIAGRA:
You may experience an increase in undesirable-ing effects and their severity. Doses above 100 mg do not increase the efficacy.
You should not take more tablets than your doctor tells you to.
Contact your doctor if you take more than you need.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, VIGRANDE can cause side effects, although not everybody gets them. Adverse reactions reported in association with use of sildenafil (the active substance of VIGRANDE) are generally mild to moderate and transient.
If you have chest pains during or after intercourse:
- Get in a semi-sitting position and try to relax.
- Do not use nitrates to treat your chest pain.
- Contact your doctor immediately.
All medicines including VIGRANDE can cause allergic reactions. You must contact your doctor immediately if you experience any of these symptoms after taking na VIGRANDE: sudden wheezing, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat.
Prolonged and sometimes painful erections have been reported after taking VIGRANDE If you have an erection that lasts more than 4 hours, you should contact a doctor immediately.
If you experience sudden decrease or loss of vision, stop taking VIGRANDE and contact your doctor immediately.
A very common side effect (likely to occur in more than 1 patient in 10) is headache.
Common side effects (likely to occur in 1 to 10 patients in 100) include: facial flushing, indigestion, vision changes (including changes in distinguishing colors, light sensitivity, blurred vision or reduced sharpness of vision) stuffy nose and dizziness.
Uncommon side effects (likely to occur in 1 to 10 patients in 1000) include: vomiting, skin rash, bleeding at the back of the eye, eye irritation, bloodshot eyes / red eyes, eye pain, double vision, abnormal sensation in the eye , irregular or rapid heartbeat, muscle pain, drowsiness, reduced sense of touch; Dizziness; ringing in the ears, nausea, dry mouth, chest pain and feeling tired.
Rare side effects (likely to occur in 1 to 10 patients in 10000) include: high blood pressure, low blood pressure, fainting, stroke, nosebleed and sudden decrease or loss of hearing. Additional adverse reactions from post-marketing experience include: pounding heartbeat, sudden death, heart attack or temporary decreased blood flow to parts of the brain. Most, but not all, of these men had heart problems before taking the drug. It is not possible to determine whether these events were directly related to sildenafil. It has also been reported cases of convulsions or seizures.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor.

5. HOW TO STORE VIGRANDE
No special storage requirements of this medicine.
Keep out of the reach of children.
Do not use VIGRANDE after the expiry date stated on the outer carton expiry date refers naposledniya day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. ADDITIONAL INFORMATION
What VIGRANDE
The active ingredient is sildenafil. Each tablet contains 100 mg of sildenafil (as citrate). Other ingredients are:
- Tablet core: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose (E 460), sodium croscarmellose, magnesium stearate.
- Coating: yellow sepifilm 3048 / hypromellose (E 464), microcrystalline cellulose Macrogol 40 stearate, titanium dioxide (E171), quinoline yellow (E 104), macrogol 6000.

VIGRANDE looks like and contents of the pack
VIGRANDE are yellow, rounded, bevelled, film-coated tablets with the number "100" on one side.

Packaging:
1 tablet (1 x 1 tablet) 4 tablets 1x4 tablets 8 tablets (2x4 tablets)
Each blister contains 1 or 4 tablets.