ZINNAT 125 mg. / 5 ml. 50 ml.

What is ZINNAT and what it is used
Zinnat is an antibiotic that is used in adults and children. It works by killing bacteria that cause infections. Belongs to a group of drugs called cephalosporins.

ZINNAT used to treat infections of the:
throat;
sinus;
middle ear;
lungs or chest;
urinary tract;
skin and soft tissue.
Zinnat can be used for:
treatment of Lyme disease (an infection that is spread by parasites called ticks).

2 What you should know before taking Zinnat
Do not take Zinnat:
if you are allergic (hypersensitive) to any cephalosporin antibiotics or any of the other ingredients Xena;
if you have ever had a severe allergic reaction (hypersensitivity reaction) to any other type of beta-lactam antibiotics (penicillins, monobactams and carbapenems).
If you think this applies to you, do not take Xena before consulting your doctor.

Take special care with Xena
Zinnat is not recommended for children under the age of three months, as its safety and effectiveness in this age group are not known.
You should watch for symptoms such as allergic reactions, fungal infections (such as Candida) and severe diarrhea (pseudomembranous colitis) while taking Xena. This will reduce the risk of possible problems. See 'Conditions you need to look "in section 4.

If you should have a blood
Zinnat can affect the results of a study of blood sugar levels or the results of a blood test called Coombs test. If you need a blood test:
Tell the person sampled acceptance Xena.

Other medicines and Zinnat
Tell your doctor or pharmacist if you are taking, have recently taken or take any other medicines, including medicines obtained without a prescription:
Drugs that are used to reduce the acid in the stomach (e.g.. Antacids, which are used to treat heartburn), may affect the operation of Zinnat;
probenecid;
Oral anticoagulants.
Tell your doctor or pharmacist if you are taking these medicines.

pill
Zinnat may reduce the effectiveness of birth control pills. If you take birth control while you are being treated with Xena must also use a barrier method of contraception (such as condoms). Ask your doctor for advice.

Pregnancy, lactation and fertility
Tell your doctor before you start taking Zinnat:
if you are pregnant, think you may be pregnant, or planning to become pregnant;
if you are breastfeeding.
Your doctor will weigh the benefits of treatment with Zinnat for you of the risks to your baby.

Driving and using machines
Zinnat may cause dizziness and other adverse reactions that reduce your attention.
Do not drive or operate machinery if you feel well.

Important information about some of the ingredients Xena
Zinnat suspension contains sugar (sucrose). If you are diabetic, this should be taken into account for your diet.
Zinnat suspension also contains aspartame, a source of phenylalanine. If you are intolerant to aspartame or have a disease called phenylketonuria (PKU):
Talk to your doctor to determine whether Zinnat is right for you.

3 How to take Zinnat
Always take this medicine exactly as prescribed by your doctor or pharmacist.
If you are not sure, ask your doctor or pharmacist.
Zinnat Take after meals. This will make the treatment more effective.
Shake the bottle before use.
Zinnat suspension can be diluted with cold fruit juices and milk drinks, but must be considered immediately thereafter.
Do not mix with hot liquids Zinnat.
For detailed instructions for preparation Xena suspension, see "Instructions for preparation" at the end of this leaflet.

usual dose
adults
The usual dose is 250 Xena mg to 500 mg twice daily depending on the severity and type of infection.

children
The usual dose of Zinnat's of 10 mg / kg (maximum dose of 125 mg) twice a day to 15 mg / kg (maximum dose of 250 mg) twice daily, depending on:
the severity and type of infection;
weight and age of the child, up to a maximum dose of 500 mg daily.
Zinnat is not recommended for children under the age of three months, as the safety and effectiveness are not known for this age group.
Depending on the disease or on your response, or the response of your child to therapy, the initial dose may change or the need for more than one course of treatment.
Patients with kidney problems
If you have kidney problems, your doctor may change your dose.
Talk to your doctor if this applies to you.
If you take more than the amount of Zinnat
If you take more than the amount of Xena may have neurological disorders and in particular likely to have a seizure is greater.
Do not delay. Immediately contact your doctor or the nearest emergency room. If possible, show them the pack of Xena.

If you forget to take Zinnat
Do not take a double dose to make up for a missed dose. Take your next dose at the usual time.

Do not stop taking Xena without consulting your doctor.
It is important to complete the full course of treatment with Xena. Do not stop taking your medicine even if you feel better unless your doctor tells you to do so. If you do not complete the full course of treatment, the infection may return.

4 Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.

Conditions you need to look
A small number of people taking Xena an allergic reaction or potentially serious skin reaction.
Symptoms of these reactions include:
severe allergic reaction. Her signs include raised and itchy rash, swelling, sometimes of the face or mouth, which can cause difficulty breathing;
skin rash, which may have blisters and looks like small targets (central dark spots surrounded by a paler area, with a dark ring around it);
widespread rash with blisters and peeling skin (this may be signs of Stevens-Johnson and toxic epidermal necrolysis);
fungal infections. Drugs such as Zinnat can cause overgrowth of yeast (Candida) in the body, which may lead to yeast infections (thrush like). This adverse reaction is more likely if you take Zinnat for an extended period of time;
severe diarrhea (pseudomembranous colitis). Drugs such as Zinnat can cause inflammation of the colon leading to severe diarrhea, usually with blood and mucus, stomach pain and fever;
reaction Yarish-Herxheimer. Some patients may develop a high temperature (fever), chills, headache, muscle aches and skin rash while on treatment with Zinnat for Lyme disease. This is known as a reaction to Yarish-Herxheimer. The symptoms usually last for a few hours or at most one day.
Immediately contact your doctor or nurse if you experience any of these symptoms.
Common side effects - may affect up to 1 in 10 people:
fungal infections (such as Candida);
headache;
dizziness;
diarrhea;
nausea;
stomach pain.
Common side effects that may show up in blood tests:
increase in white blood cells (eosinophilia);
increase in liver enzymes.
Uncommon side effects - may affect up to 1 in 100 people:
nausea;
skin rashes.
Uncommon side effects that may show up in blood tests:
reduction in the number of platelets (cells that help the blood to clot);
decrease the number of white blood cells;
positive Coombs test.
Other side effects
Other side effects have occurred in a very small number of people but their exact frequency is unknown:
severe diarrhea (pseudomembranous colitis);
allergic reactions;
skin reactions (including severe);
high temperature (fever);
yellowing of the whites of the eyes or skin;
inflammation of the liver (hepatitis).
Side effects that may occur through blood tests:
very rapid destruction of red blood cells (hemolytic anemia).
If you get side effects
Tell your doctor or pharmacist. This includes all listed in this leaflet.

5 How to store Zinnat
Before reconstitution, the suspension was kept below 30 ° C.
After preparation, the suspension should be kept in a refrigerator at 2 ° C to 8 ° C.
Do not use the suspension, made more than 10 days.
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton after "EXP". The expiry date refers to the last day of that month.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment

6 Package Contents and more information
What does Zinnat
The active substance is in the form of cefuroxime cefuroxime axetil. Each 5 ml of reconstituted suspension contains 125 mg Zinnat or 250 mg of cefuroxime.
The other ingredients are aspartame, xanthan gum, acesulfame potassium, stearic acid, sucrose, fruity, povidone K30.
Zinnat looks like and contents of pack
Zinnat 125 mg / 5 ml granules for oral suspension
Zinnat 125 mg / 5 ml granules for oral suspension is a white to off-white granules. After the preparation is obtained as a white to pale yellow suspension.
One pack contains a bottle of Zinnat granules for suspension, measuring cup and measuring spoon of transparent plastic. Before use intake spoon in the package to measure the prescribed dose. Filled to the brim scoop contains 5 ml suspension, which is equivalent to 125 mg of active substance.
The total amount of the slurry after preparation was 50 ml.
Zinnat 250 mg / 5 ml granules for oral suspension
Zinnat 250 mg / 5 ml granules for oral suspension is a white to off-white granules. After the preparation is obtained as a white to pale yellow suspension.
One pack contains a bottle of Zinnat granules for suspension, measuring cup and measuring spoon of transparent plastic. Before use intake spoon in the package to measure the prescribed dose. Filled to the brim scoop contains 5 ml suspension, which is equivalent to 250 mg of active substance.
The total amount of the slurry after preparation was 50 ml or 100 ml.

Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder:
GlaxoSmithKline