CIRCADIN table. 2 mg. 21 table

CIRCADIN WHAT IS AND WHAT IT IS USED

The active substance of Circadin, melatonin, belongs to the natural hormones produced by the body.

Circadin is indicated as monotherapy for the short-term treatment of primary insomnia (difficulty falling asleep or staying asleep, or poor quality of sleep for at least one month), characterized by poor quality of sleep in patients aged 55 and over 55.

 BEFORE YOU TAKE CIRCADIN

Do not take Circadin

 If you are allergic (hypersensitive) to melatonin or any other ingredients of Circadin.

Take special care with Circadin

 If sleepiness can be dangerous to your safety;

  If you have liver problems;

  If you have kidney problems;

  If you have an autoimmune disease (where the body is 'attacked' by its own immune system)

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, before starting treatment, as they can affect the action of Circadin. These drugs include hypnotics and tranquilizers (eg, benzodiazepines), fluvoxamine, thioridazine and imipramine (used to treat depression or psychiatric problems), estrogen (contraceptives or hormone replacement therapy), cimetidine and psoralens (used to treat skin problems such as for example. psoriasis).

 Taking Circadin with food and drink

Take Circadin after eating. Do not drink alcohol before, during and after taking Circadin.

Pregnancy and lactation

Ask your doctor or pharmacist before taking any medicine. Do not take Circadin, if you are pregnant or suspect you may be pregnant.

Do not breast-feed during treatment with Circadin.

Driving and operating machinery 

Circadin may cause drowsiness. If you are affected, do not drive or operate machinery. If you're constantly sleepy, you should consult your doctor.

Important information about some of the ingredients of Circadin

Each prolonged-release tablet contains 80 mg lactose monohydrate. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.

 HOW TO TAKE CIRCADIN

Always take Circadin exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.

The usual dose is one tablet

Circadin daily by mouth after eating 1-2 hours before bedtime, for 3 weeks. Swallow the tablet whole. Circadin tablets should not be crushed or cut in half.

If you take more Circadin than

If you accidentally take too much medicine, contact your doctor or pharmacist.

Taking more than the recommended daily dose may make you feel drowsy.

If you forget to take Circadin

If you miss a dose, take another as soon as you remember before going to sleep until it is time for your next dose, then go on as before take a double dose to make up for a missed dose. If you stop taking Circadin There are no known harmful effects upon discontinuation or premature discontinuation. There is no known use of Circadin to cause any withdrawal effects after treatment completion have any further questions on the use of this product, ask your doctor or pharmacist.

 POSSIBLE SIDE EFFECTS

Like all medicines, Circadin can cause side effects, although not everybody gets them. The following events are considered to be uncommon (ie likely to occur in less than 1 in 100 patients):

Irritability, nervousness, restlessness, insomnia, abnormal dreams, migraine, psychomotor hyperactivity (restlessness associated with increased activity), dizziness, somnolence (tiredness), abdominal pain, constipation, dry mouth, hyperbilirubinaemia (changes in blood composition that can cause yellowing of the skin or eyes (jaundice), hyperhidrosis (excessive sweating), asthenia (feeling of weakness) and weight gain.

The following events are considered to be rare (ie, likely to occur in less than 1 in 1000 patients): Herpes zoster (shingyls), leukopenia, thrombocytopenia, hypertriglyceridemia, mood swings, aggression, agitation, crying, early morning awakening, increased libido (increased sex drive), memory impairment, impaired attention, poor quality sleep, reduced visual acuity (blurred vision), blurred vision, increased lacrimation (watery eyes), positional vertigo (dizziness when standing up), hot flushes, gastrointestinal upset, vomiting, abnormal bowel sounds, flatulence (gas), salivary hypersecretion (excess saliva), halitosis (bad breath), abnormal liver function tests (elevated liver enzymes), eczema, erythema (skin rash) rash pruritic (itchy rash, pruritus (itching), dry skin, nail disorder, night sweats, muscle cramps, neck pain, priapism (increased duration of erection) and fatigue (tiredness). If any of the side effects gets serious, or If you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

 STORAGE CIRCADIN

Keep out of reach of children. 

Circadin Do not use after the expiry date stated on the carton.

The expiry date refers to the last day of that month.

 Additional Information

What Circadin

 The active ingredient is melatonin. Each prolonged-release tablet contains 2 mg of melatonin.

  The other ingredients are ammonio methacrylate copolymer type B, calcium phosphate, lactose monohydrate, colloidal anhydrous silica, talc and magnesium stearate. 

Circadin looks like and contents of pack

Circadin 2 mg prolonged-release tablets are available as white to off-white, round, biconvex tablets. Each carton contains one blister of 20 or 21 tablets. Not all pack sizes may be marketed.