WHAT doxazosin Aurobindo AND WHAT IT IS USED
Doxazosin belongs to a group of drugs known as vasodilators. They cause dilation of blood vessels, leading to lowering of blood pressure.
Doxazosin also reduces the tension in the muscle tissue of the prostate and urinary tract.
Doxazosin is used for treatment of:
high blood pressure;
symptoms of an enlarged prostate.
2. BEFORE YOU TAKE doxazosin Aurobindo
Do not take doxazosin Aurobindo:
if you are allergic (hypersensitive) to doxazosin, other medicines in the same group (called quinazolines such as prazosin and terazosin) or any of the other ingredients of doxazosin Aurobindo;
if you have ever had a condition known as "postural hypotension", which is a form of low blood pressure causing dizziness or dizziness when standing up from a sitting or lying position;
if you have an enlarged prostate and it is accompanied by any of the following: any form of obstruction or blockage of the urinary tract, prolonged urinary tract infection or bladder stones;
if you are breastfeeding;
if you have enlarged prostate gland (benign prostatic hyperplasia) and have low blood pressure;
if you have overflow incontinence (not feel urge to urinate) or anuria (your body does not produce urine) with or without kidney problems.
Take special care with doxazosin Aurobindo
Tell your doctor before you start taking this medicine in the following cases:
if you suffer from serious heart problems such as severely reduced function of the heart or feeling trapped or chest pain (angina pectoris);
if you follow a strict diet with limited salt intake;
if you are using diuretics;
if you have problems with your kidneys or liver.
If you have an operation on the eye due to cataracts (clouding of the lens) please inform your eye specialist before the operation that you are using or have used doxazosin Aurobindo. This is necessary as doxazosin Aurobindo may cause complications during the surgery, which can be controlled if your specialist is prepared in advance.
Important information about doxazosin Aurobindo
The possibility of too rapid drop in blood pressure is greatest at the beginning of treatment or when increasing the dose. You can experience it as dizziness or less fit as a change in body position. To reduce this risk, your doctor will check your blood pressure thoroughly at the beginning of treatment and dose increases. So at the beginning of treatment should avoid situations where dizziness or weakness can lead to injury.
Doxazosin Aurobindo also can affect the results of some blood tests and urine. If you have a blood test or urine tell that you are taking doxazosin Aurobindo.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription:
Some patients taking alpha-blockers to treat high blood pressure or enlarged prostate may experience drowsiness or dizziness, which may be caused by low blood pressure upon sitting or standing up quickly. Some patients have shown these symptoms when taking drugs for erectile dysfunction (impotence) with alpha-blockers. To reduce the likelihood of these symptoms, you should be receiving regular daily dose of your alpha blocker before you start taking medicines for erectile dysfunction;
Doxazosin Aurobindo may lower your blood pressure even more if you are already taking other medicines to treat high blood pressure such as terazosin or prazosin;
Nitrates (medicines for heart problems) as nitroglycerin and isosorbide nitrate may enhance the blood pressure lowering effect;
Some painkillers for rheumatism (called NSAIDs) such as naproxen, ibuprofen or any other anti-inflammatory analgesic, can reduce the blood pressure lowering effect;
Drugs that can affect hepatic metabolism, such as cimetidine (medicine for the stomach problems).
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
If you are pregnant or think you are pregnant you should contact your doctor before taking doxazosin Aurobindo. Doxazosin Aurobindo should be used during pregnancy only if your doctor decides that the benefit outweighs the potential risk to the fetus.
You should not breast-feed while taking doxazosin Aurobindo.
Driving and using machines
Doxazosin can sometimes cause dizziness or fainting. In that case, you should be cautious when engaging in activities requiring attention such as driving, operating machinery or working at height. If you are unsure whether doxazosin Aurobindo has a negative impact on your driving, ask your doctor.
Important information about some of the ingredients of doxazosin Aurobindo
This medicinal product contains lactose. If you are told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
3. HOW TO TAKE doxazosin Aurobindo
Always take doxazosin Aurobindo exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
The usual dose is:
HIGH BLOOD PRESSURE
The initial dose is 1 mg per day (= 24 hours) as a single dose. After 1 to 2 weeks is usually increased to 2 mg as a single daily dose. This dosage is also administered 1-2 weeks. If necessary, the dose may be further increased to 4, 8 or 16 mg daily, until a desired reduction in blood pressure. The maximum daily dose is 16 mg.
Preferably starting dose should be taken at bedtime; this will reduce the chance of getting a sense of vertigo or dizziness.
enlarged prostate
The initial dose is 1 mg per day (= 24 hours) as a single dose. Then, the usual dose is 2 mg or 4 mg per day. Under certain circumstances can be increased to 8 mg daily.
The tablets should be taken as a single dose each day (= 24 hours). The tablets should be taken with enough water.
If you take more than the amount of doxazosin Aurobindo
If you take more than the prescribed dose, you must inform your doctor and / or pharmacist. If you feel very dizzy or think you might faint, immediately you have to lie upside down.
If you forget to take doxazosin Aurobindo
If you forget to take a tablet, skip it and then take your next tablet at the usual time. If you are unsure ask your doctor or pharmacist.
Do not take a double dose to make up for a missed tablet.
If you stop taking doxazosin Aurobindo
If you suddenly stop taking doxazosin, the complaints which have suffered prior to treatment may reappear. Therefore, it is better not end suddenly taking this medicine. Your doctor will reduce the dose gradually. If you are unsure ask your doctor or pharmacist.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, doxazosin Aurobindo can cause side effects, although not everybody gets them.
Some of the side effects can be serious.
If any of the following, stop taking this medicine immediately and contact your doctor or go to the emergency room at the nearest hospital:
Allergic reactions such as wheezing, shortness of breath, severe dizziness or collapse, swelling of the face or throat or serious skin rash with red spots or blisters;
Chest pain, fast or irregular heartbeat, heart attack or stroke;
Yellowing of the skin or whites of the eyes caused by liver problems;
Unusual bleeding or bruising caused by low platelet count.
These side effects are uncommon (affects 1 to 10 in 1000 people) or rare (affects 1 to 10 persons per 10,000).
Other side effects:
Very common (affecting more than 1 in 10 people):
dizziness;
headache.
Common (affects 1 to 10 in 100 people):
respiratory tract infection;
urinary tract infection, urinary incontinence (urinary incontinence);
loss of appetite;
anxiety, insomnia, nervousness;
dizziness, numbness or tingling of hands and feet (paresthesia), drowsiness;
feeling dizzy or spinning (vertigo);
feeling or sensation of irregular heartbeat (palpitations), increased heart rate;
low blood pressure or lowering blood pressure when standing up from a sitting or lying position (postural hypotension);
inflammation of the airways in the lungs, coughing, shortness of breath, stuffy and / or runny nose;
abdominal pain, indigestion, dry mouth, nausea, diarrhea;
itching (pruritus);
back pain, muscle pain (myalgia);
inflammation of the bladder (cystitis);
a feeling of weakness (asthenia), chest pain, flu-like symptoms;
swelling of ankles, feet or toes (peripheral edema), fatigue, malaise.
Very rare (affects less than 1 in 10,000 people):
low platelet count;
low white and red blood cells;
blurred vision;
decreased heart rate;
bronchospasm;
biliary obstruction (cholestasis), inflammation of the liver (hepatitis);
yellowing of the skin or whites of the eyes caused by liver problems or blood;
atypical results of liver function tests;
elevated blood levels of urea and creatinine;
blockage of normal flow of bile (cholestasis) which may cause jaundice (yellowing of the skin or whites of the eyes);
liver inflammation (hepatitis);
hives (urticaria);
violation of urine output, need to urinate at night, increased urine output;
temporary increase of the breasts (gynecomastia), persistent painful erection.
Not known (from the available data can not be estimated frequency):
it is possible to occur problems with eyes during cataract surgery (clouding of the lens of the eye). See section "Take special care with doxazosin Aurobindo"
Taste disorders;
Reduced or no semen during ejaculation, dark urine after ejaculation (retrograde ejaculation).
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE doxazosin Aurobindo
Keep out of reach of children.
Do not use doxazosin Aurobindo after the expiry date stated on the blister, bottle or carton after "EXP". The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. FURTHER INFORMATION
What doxazosin Aurobindo
The active substance is doxazosin. Each tablet contains 1/2/4 / mg doxazosin (such doksazosinov mesylate).
Other ingredients are: Microcrystalline cellulose, anhydrous lactose, sodium starch glycolate (type A), magnesium stearate.
Looks like doxazosin Aurobindo and contents of the pack
Aurobindo doxazosin 1 mg tablets:
White to off-white, round, biconvex, uncoated tablets debossed with "N" on one side and "01" on the other.
Aurobindo doxazosin 2 mg tablets:
White to off-white capsule-shaped, uncoated tablets debossed "H02" on one side and scored on the other.
The tablet can be divided into two equal halves.
Aurobindo doxazosin 4 mg tablets:
White to off-white, diamond, uncoated tablets debossed "N03" on one side and scored on the other.
The tablet can be divided into two equal halves.
PVC-PVDC Aluminium blisters:
Packing: 10, 14, 15, 20, 28, 30, 50, 56, 60, 90, 98, 100 and 140 tablets.