
KADUET a combination preparation containing medicinal substances belonging to the group of medicines called calcium channel blockers, and statins.
What used KADUET
KADUET be used in patients with high blood pressure (hypertension) who are at risk of heart disease in the presence of additional cardiovascular risk factors and normal to slightly elevated cholesterol levels, without clinical evidence of coronary artery disease should sartseto.KADUET used only when diet and other measures (exercise) are not enough.
KADUET should not be used:
If you have an allergic reaction to amlodipine besylate, atorvastatin calcium or to any of the excipients in the formulation of the drug described above or similar drugs used to lower cholesterol or blood pressure.
If the answer to any of the following questions is YES, tell your doctor before taking KADUET as this medicine may not be suitable for you.
If you have or have had liver disease or if you have abnormal results of blood tests for liver function.
If you drink alcohol in large quantities.
If you have any of the following symptoms: muscle pain, cramps or muscle weakness, especially if associated with fever and malaise. In this case, stop taking KADUET and consult a physician immediately.
If you have kidney problems or thyroid hormones, personal or family history of muscle disorders, or if you have muscle problems during previous treatment with other drugs that lower cholesterol (eg statins or other medications known as fiber) if you are over 70 years. In all these cases, your doctor may order blood tests before and during treatment with KADUET.
Tell your doctor immediately if you develop a skin rash, swelling of the face and body, wheezing or wheezing during treatment KADUET.
Pregnancy
KADUET should not be taken during pregnancy unless your doctor recommends otherwise. Women of childbearing potential have to use effective contraception. Contact your doctor immediately if you become pregnant, think you are pregnant or plan to become pregnant while taking KADUET.Posavetvayte your doctor or pharmacist before using any medicine if you are pregnant.
Breastfeeding
While using KADUET not recommended to breastfeed. Ask your doctor or pharmacist for advice before taking any medicine while breast-feeding.
Driving and using machines:
Clinical experience indicates that it is unlikely KADUET impair your ability to drive or operate machinery.
Taking other medicines:
Before you begin taking any new medicine is KADUET should talk to your doctor. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicine, even without a prescription.
KADUET and certain other medicines can affect each other (interaction) as: Drugs that affect the immune system such as cyclosporine Some antibiotics, for example. rifampicin or "macrolide antibiotics", eg. erythromycin, telithromycin, or some medicines used to treat diseases caused by fungi such as ketoconazole, itraconazole.
Medicines to control cholesterol levels as fibrates, niacin, kolestipol.Lekarstva adjustment sardechiniya rhythm, eg. digoxin Protease inhibitors used to treat HIV Warfarin (a medicine to thin the blood) Oral contraceptives antacids (for indigestion)
Nefazodone (antidepressant)
Stiripentol (a medicine used to treat epilepsy)
Taking KADUET food and drink
KADUET tablets can be taken at any time of the day with or without food.
KADUET not take large quantities of grapefruit juice (more than 1.2 liters a day for 5 days), as this juice contains many chemicals that can increase the amount of one of the active substances in your body KADUET.
It is not recommended alcohol consumption while taking KADUET.
Always KADUET exactly as your doctor has instructed. If you are not sure, ask your doctor or pharmacist.
The usual starting dose is one tablet KADUET of 5 mg / 10 mg once daily. If necessary, your doctor may increase this dose to 10 mg / 1 OMG. For this dosage, your doctor will prescribe KADUET 10 mg/10 mg tablets.
If you feel that the effect of KADUET is too strong or too weak, talk to your doctor or pharmacist.
KADUET tablets should be swallowed by mouth with a drink of water. The tablets can be taken at any time of the day with or without food.
It is recommended that follow your doctor recommended diet, not smoking and doing regular exercise.
If you still are not sure about anything, ask your doctor or farmatsevt.Ako take more than the required amount KADUET: Call your doctor immediately or go to the nearest hospital emergency room. Take a pack of KADUET is you, even if it does remain tablets.
If you forget to take KADUET:
It is important to take your tablets regularly KADUET at the same time each day. If you forget to take a dose, take it as soon as you remember unless it is time for your next dose. In this case, just continue with the next dose as usual. Do not take 2 doses at the same time to make up for the dose that you missed
KADUET, like all drugs, may cause some side reaktsii.Nezhelanite effects listed below have occurred in some patients when amlodipine and atorvastatin were administered alone
Common side-effects which may affect more than one person in 100 are listed below:
Insomnia (difficulty sleeping)
Headache, drowsiness, dizziness, decreased skin sensitivity to touch or pain, numbness or tingling of the fingers and toes
Palpitations
Flushing
Nausea, abdominal pain, indigestion, diarrhea, constipation, gas
Allergic reactions, skin rash or itching
Muscle pain, back pain, joint pain
fatigue *, edema (swelling of the ankles as), weakness, chest pain
Increased the results of blood tests for liver and muscle function
If you have muscle weakness, muscle cramps, tenderness or pain in the muscles, stop taking KADUET n tell your doctor immediately.
If any of the side effects become persistent or troublesome, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Keep your medicine at a temperature below 30 ° C. Keep all medicines out of reach of children! Store in original container.
Do not use after the expiry date stated on the packaging.
Medicinal ingredients are:
Amlodipine (amlodipine) in the form of amlodipine besilate and Atorvastatin (atorvastatin) in the form of atorvastatin calsium trihydrate.
Each tablet contains 5 mg amlodipine contains 10 mg and atorvastatin.
The ingredients are:
Tablet: calcium carbonate, croscarmellose sodium, microcrystalline cellulose, pregelatinized starch, polysorbate 80, hydroxypropyl cellulose, colloidal anhydrous silica, magniziev stearatFilm coating: Opadry II white (polyvinyl alcohol, titanium dioxide (EI7I). Macrogol / PEG 3000, talc)