TOBRAMIZIL ointment 3 mg.

WHAT TOBRAMIZIL AND WHAT IT IS USED
Tobramycin is an antibiotic of the aminoglycoside group, which is active against a large number of microorganisms that commonly cause infections of the eye.
Tobramizil eye ointment is administered for treatment of superficial infections of the eye (eg. Conjunctivitis) and surrounding tissues caused by bacteria sensitive to the action of tobramycin.

2. BEFORE YOU USE TOBRAMIZIL
Do not use Tobramizil if you are allergic (hypersensitive) to tobramycin or any of the other ingredients of Tobramizil.
Take special care with Tobramizil
Application on the eye of the antibiotics of this group can cause an allergic reaction in some patients, most often manifested by itching, redness and swelling of the eyelid, lacrimation. In this case, use of the product should be discontinued. You need to know that if you have or have had allergic to other antibiotics of this group (eg. Gentamicin), the possibility of an allergic reaction is higher.
Continuous use of the product may lead to the development of resistant microorganisms and accordingly to reduce the effects of the treatment. Sometimes it can develop additional infection by other organisms, including fungi. In these cases, the doctor will appoint an appropriate treatment.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. When co-administered with other aminoglycoside antibiotics, you should tell your doctor who will decide whether it is necessary to monitor their overall level in the blood.
You should not wear contact lenses in case of eye infection and during treatment with the product.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
Treatment with aminoglycoside antibiotics may cause harm to the auditory nerve and cause deafness. The advent of tobramycin in the blood of topical ocular administration, however, is weak and it is believed that this risk using Tobramizil is low. However, it is recommended to use the product during pregnancy and lactation can be appointed only if clearly needed and after careful consideration of the benefit / risk ratio.

Driving and using machines
It is possible appearance of temporary blurred vision or other vision disorders that affect the ability to drive and use machines. If this happens, the patient should wait until the vision clears and then to drive or operate machinery.

3. HOW TO USE TOBRAMIZIL
Always use Tobramizil just as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.
The dose and duration of treatment prescribed by the doctor.

Adults, adolescents and the elderly
Recommended dose for mild and moderate Infections small amount of the drug (strip with a length of about 1.5 cm) into the affected eye / eye two or three times a day.
The recommended dose in severe Infections small amount of the drug (strip length is about 1.5 cm) is placed in the eye / eye every three to four hours during the first two days, then two or three times daily until the infection is cured.
The usual duration of treatment is 7-10 days.
There is no need dose adjustment in the elderly.

Use in children
The product can be used in children at the same dosage as in adults.
Use in patients with liver and kidney disease
In these patients do not require a change in the recommended dose, as has disclosed high concentrations of the active substance in the blood after administration in the eye. If simultaneously with the product you are treated with other aminoglycosides, your doctor will consider the need to monitor the total serum concentration.
Method of administration Tobramizil eye ointment is applied as follows:
before placing the drug it is necessary to wash your hands.
Tilt your head back
place your finger on the cheek just below the eye and gently pull the lower eyelid
down so that it forms a 'pocket' between the eye and him.
in this "pocket" put the amount of medicine prescribed by the doctor.
end of the tube should not touch the eye, eyelid or other surrounding tissues and surfaces, as this may contaminate the medicine.
after placing the drug look down, blink a few times to allow it to cover the entire ocular surface, then close the eye for a few seconds.
After use, tighten the tube immediately.
If you are treated with other products intended for use in the eye, put them in series in at least 5-10 minutes, such as ointment should be placed last.
If you use more than the amount Tobramizil
Do not take your medicine more often or for longer periods than indicated by the doctor to avoid overdose. However, if you accidentally have used more than the prescribed dose, contact your doctor or pharmacist although usually enough eye wash thoroughly with lukewarm boiled water.
In just following the instructions for use of the product is very unlikely that an overdose. After oral ingestion inadvertently, the amount of which will go in the blood is also null and void.
If you forget to use Tobramizil
Do not use more than the required amount to make up for missed application. Apply the usual dose as soon as possible after you remember and continue treatment as usual.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Tobramizil can cause side effects, although not everybody gets them. If this happens, tell your doctor. That frequency means: Common (≥ 1/100, <1/10) -At more than one patient in 100 and less than one in ten; very rare (<1/10 000) - in less than 1 patient in ten thousand. When treated with the product may occur following side effects:
Eye disorders
Chesti- itching and redness, tearing; Rare: ocular allergic reactions, eye discharge, feeling of discomfort in the eyes, swelling and redness of the eyelids, other problems with the eyelid. If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.

5. HOW TO STORE TOBRAMIZIL
Keep out of reach of children.
Do not use Tobramizil after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Period of use after first opening of the package 28 days.
Do not store above 25 ° C.
Do not use Tobramizil, if you notice that the ointment has changed in appearance or shows other signs of deterioration. Ask your pharmacist for advice.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. FURTHER INFORMATION
What Tobramizil
Active substance 1g ointment: Tobramycin (ToYramycin) 3,0 mg (as sulphate / as sulfate)
Other ingredients are: Methyl parahydroxybenzoate, Propyl parahydroxybenzoate, paraffin, liquid paraffin, white soft.
Tobramizil looks like and contents of the pack
Tobramizil ointment eye ointment is a white to pale yellow color, with uniform consistency without agglomerates and air bubbles.
Tobramizil eye ointment is packaged in lacquered aluminum tubes with handpiece closed with plastic screw cap.
A tube with a package leaflet in the box.