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Egilok 25mg. 60 tablets

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What Egilok is and what it is used for
Metoprolol, the drug substance of Egilok, is so-called beta-blocker, a drug that affects the sympathetic part of the nervous system (the autonomic nervous system, the central nervous system that regulates your vital functions). This medicine is used to treat ischemic heart disease (angina), hypertension (high blood pressure), myocardial infarction, some types of cardiac arrhythmias (irregular heartbeat), hyperthyroidism (to reduce heart rhythm ) and migraine Eigelock should not be used in acute angina attacks Egiloc can reduce cardiovascular mortality in patients with high blood pressure In post-myocardial infarction conditions this medicine is recommended for lactic of subsequent myocardial infarction.

2. What you need to know before you start taking Egilok
Do not take Egilok:

If you are allergic to metoprolol or any of the other ingredients of this medicine (listed in section 6) or to another medicine containing a beta-blocker;
If you suffer from worsening heart failure;
In cardiogenic shock;
If you suffer from severe cardiac arrhythmia or heart conduction disorder;
If you suffer from severe peripheral arterial disease (atherosclerosis);
If you are on the so-called beta-agonist treatment due to severe heart failure.
Warnings and precautions
Talk to your doctor or pharmacist before taking Egiloc:

if you suffer from a conductive heart attack or arrhythmia;
if you have mild or moderate heart failure;
if you suffer from severe liver disease;
if you are pregnant or breast-feeding;
if you take other medicines for arrhythmia, heart disease or hypertension at the same time;
if you are taking tranquilizers;
if you are going to have a general anesthetic surgery;
if you regularly consume alcoholic beverages;
if you suffer from chronic airway disease and / or use bronchodilators (bronchodilators) such as terbutaline, salbutamol, fenoterol, salmeterol;
if you are taking medicines (such as ergotamine) to stimulate uterine contractions;
if you use anti-inflammatory and analgesic medicines (eg diclofenac, piroxicam, flurbiprofen) for inflammation and joint pain;
if you take certain medicines containing female sex hormones (eg oral contraceptives, hormone replacement medicines);
if you suffer from diabetes mellitus and are being treated (with tablets or insulin);
if you are taking medicines that affect the degradation of metoprolol (eg cimetidine, hydralazine, paroxetine, fluoxetine, sertraline, rifampicin or barbiturates);
if you use eye drops containing a beta-blocker (eg timolol, betaxolol, levobunolol);
if you are prescribed so-called MAOIs to treat Parkinson's disease or depression.
Other medicines and Egilok
Tell your doctor if you are taking, have recently taken or might take any other medicines in the future.
Interactions with other medicinal products are described above in the "Warnings and Precautions" section.

Egilok with food, drinks and alcohol
Concomitant administration of Egglock with food and drink as well as its self-administration does not affect its absorption and its healing effects.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Metoprolol did not show effects damaging the fetus in animal experiments.
The drug substance is excreted in breast milk.
Since there is insufficient data on the safety of the use of Egilok in pregnant women and nursing mothers, Egiloc should not be taken by them unless the treating physician determines that the benefit of the medicine outweighs the potential risks.
If administered, treatment with Egiloc should be discontinued 2-3 days before the expected birth. If treatment is absolutely necessary, the newborn should be carefully observed for 2-3 days after birth.

Driving and using machines
Egilok can adversely affect these activities, especially at the beginning of treatment and if alcohol is consumed during treatment, therefore the dose at which these activities can be performed is determined individually by your doctor.

3. How to take Egilock
Always take this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Tablets can be taken with or without food.
Dose determination becomes individual.

The recommended doses are as follows:
Hypertension:
The recommended starting dose is 2 x 25-50 mg daily (morning and evening). If necessary, your doctor may increase the dose to 2 x 100 mg or add other antihypertensive medicines in combination.

Stomach (frog):
The recommended starting dose is 2-3 x 25-50 mg in the morning (at noon) and in the evening. If necessary, your doctor may increase the dose to 2 x 100 mg or add other anti-skeletal medicines in combination.

Maintenance treatment following myocardial infarction:
The recommended maintenance dose is 2 x 50-100 mg in the morning and in the evening.

Arrhythmia:
The recommended starting dose is 2-3 x 25-50 mg in the morning (at noon) and in the evening. If necessary, your doctor may increase the dose to 2 x 100 mg or add other anti-arrhythmic drugs in combination.

Hyperthyroidism:
The recommended daily dose is 3-4 x 50 mg in the morning, at noon and evening (and possibly at bedtime).

Functional cardiac disorders with heart palpitations:
The recommended daily dose is 2 x 50-100 mg (morning and evening).

Prophylaxis of migraine attacks:
The recommended daily dose is 2 x 50-100 mg (morning and evening).

Do not discontinue treatment with Egilok by yourself.
Check with your doctor if the effects of Egilock seem too strong or weak.

Hepatic insufficiency
For liver diseases, a lower starting dose is recommended.

Kidney failure
No dose reduction is required in elderly patients and those with renal insufficiency

Use in children and adolescents
Clinical experience with metoprolol treatment in children and adolescents is limited.

If you take more than the necessary dose of Egilok
If you have taken more than the prescribed dose, tell your doctor immediately.

If you forget to take Eyglok
If you forget to take Eyglok in the usual time, take it as soon as possible, but only if there is enough time until the next intake. However, if it is time for the next dose, do not take a double dose to make up for the missed dose. This will not happen, and you risk overdosing.

If you stop taking Egilok
If you are taking Eggiloc, never stop taking the tablets sharply as treatment may only be discontinued if your doctor prescribes it with a gradual dose reduction.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.

If any of the following symptoms occur, stop taking the medicine and tell your doctor immediately or refer to the nearest emergency department:

swelling of the hands, feet, lips, mouth or throat and difficulty swallowing or shortness of breath;
seizure or seizure-like malaise.
These side effects are very severe but occur in very rare cases. These are signs of severe hypersensitivity (allergic reaction) to Egilock, and urgent medical attention or hospitalization may be required.

Urticaria (hives).
It can also be a sign of an allergic reaction. Stop taking tablets immediately and tell your doctor about your future treatment. To avoid serious consequences, talk to your doctor immediately if the rashes are severe and cover the whole body.

The frequency of the above side effects is very low.
Check with your doctor if any of the following occurs:
The terms used below for the incidence of adverse reactions are defined as follows:
Very common (may affect more than 1 in 10 people):

fatigue.
Common (may affect up to 1 in 10 people):

dizziness, headache;
slow heart rate (less than 50 beats / minute), low blood pressure when sitting or standing (sometimes fainting), cold extremities, palpitations;
nausea, abdominal pain, diarrhea, constipation;
breathlessness with physical effort;
Uncommon (may affect up to 1 in 100 people):

abnormal sensations, muscle spasms, depression, impaired ability to concentrate, drowsiness, sleep disturbances (insomnia), nightmares;
worsening of symptoms of heart failure, moderate heart conduction disorders; swelling of the legs, chest pain;
vomiting;
skin rashes (hives, psoriasis and dystrophic skin damage), increased sweating;
bronchospasm (even without the presence of some pulmonary disease);
weight gain.
Rare (may affect up to 1 in 1,000 people):

irritability and anxiety, sexual problems;
arrhythmia, cardiac conduction disorders;
dry mouth, altered liver function test results;
hair loss;
rhinitis;
visual disturbances, dry eye and / or eye irritation, conjunctivitis.
Very rare (may affect up to 1 in 10,000 people):

memory loss, memory disorders, confusion, hallucinations, change in taste;
gangrene, based on pre-existing peripheral circulatory disorders in the legs;
light sensitivity, psoriasis stimulation;
noise in the ears;
decreased number of blood platelets;
joint pain.
Taking this medicine should be discontinued if any of the side effects listed above are long and the cause can not be unambiguously determined.
Tell your doctor or pharmacist immediately if the symptoms of your heart failure (difficulty in breathing, swelling of the calf) get worse during treatment.
Your heartbeat may be delayed during treatment. This is a normal phenomenon. However, tell your doctor if you are concerned about it or if you are well, but your heart rate falls below 55 beats per minute.
Tell your doctor immediately if you have ischemic heart disease and stiff chest pain occurs more often than usual and / or under unusual circumstances and / or lasts longer and does not decrease by taking your usual medication.
Always tell the medical staff or anesthesiologist that you are taking Egilock if you are urgently needed to treat a severe allergy or are hospitalized for surgery.
 How to Store Egilock
Store below 25 ° C. Keep away from moisture.
Keep out of the reach and sight of children.
Do not use the medicine after the expiry date which is stated on the pack. The expiry date refers to the last day of that month.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.

6. Package Contents and Additional Information
What Egilock contains:
The active substance is: 25 mg, 50 mg or 100 mg metoprolol tartrate in each tablet.
The excipients are: magnesium stearate, povidone, colloidal anhydrous silica, sodium starch glycolate (type A), cellulose microcrystalline.

What Eyglok looks like and contents of the pack:
Description:
25 mg: White or almost white, without or almost odorless, round, biconvex, divisible tablets with two cross-sectional markings for splitting quarters on one side and marked E and 435 on the other side.
The tablet may be divided into equal doses.

50 mg: White or almost white, without or almost odorless, round, biconvex, divisible tablets with a divider to split halves on one side and marked with E and 434 on the other side.
The tablet may be divided into equal doses.

100 mg: White or almost white, with or almost odorless, round, biconvex, bevelled, divisible, scored to split halves on one side and marked with E and 432 on the other side.
The tablet may be divided into equal doses.

Package:

25 mg and 50 mg: 40, 50, 60, 70, 80, 90, 100 or 120 tablets;
100 mg: 20, 30, 40, 50, 60, 70, 80, 90, 100 or 120 tablets in a brown glass packet, closed with a white protective polyethylene cap with an impact pad, in a cardboard box.

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